Yuxuan Wang, MD, PhD

Primary Academic Title

Assistant Professor of Oncology

Research Interests

Cancer Genetics and Epigenetics, Circulating tumor DNA

Selected Publications

• Wang Y, Joshu CE, Curtis SD, Douville C, Burk VA, Ru M, Popoli M, Ptak J, Dobbyn L, Silliman N, Coresh J, Boerwinkle E, Prizment A, Bettegowda C, Kinzler KW, Papadopoulos N, Platz EA, Vogelstein B. Detection of cancers three years prior to diagnosis using plasma cell-free DNA. Cancer Discov. 2025 Sep 4;15(9):1794-1802

• Wang Y, Douville C., Cohen JD, Mattox A, Curtis S, Silliman N, Popoli M, Ptak J, Dobbyn L, Nehme N, Dudley JC, Summers M, Zhang M, Ho-Pham LT, Tran BNH, Tran TS, Nguyen TV, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B*. Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules. Proc Natl Acad Sci USA 2023;120(15)

• Wang Y, Li L, Cohen J, Kinde I, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Tie J, Gibbs P, Tomasetti C, Kinzler KW, Papadopoulos N, Vogelstein B, Olsson L. Prognostic potential of circulating tumor DNA in postoperative surveillance of non-metastatic colorectal cancer.  JAMA Oncology.  2019;5(8):1118-1123

• Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Shih IM, Wang TL, Kurman R, Springer S, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Angarita A, Lycke M, Jochumsen K, Afsari B, Levine D, Jardon K, Zeng X, Arseneau J, Fu L, Diaz LA, Karchin R, Tomasetti C, Kinzler KW, Vogelstein B, Fader AN, Gilbert L, Papadopoulos N. Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers.  Science Translational Medicine.  2018;10(433)

• Wang Y, Springer S, Zhang M, McMahon KW, Kinde I, Dobbyn L, Ptak J, Brem H, Chaichana K, Gallia GL, Gokaslan ZL, Groves ML, Jallo GI, Lim M, Olivi A, Quinones-Hinojosa A, Rigamonti D, Riggins GJ, Sciubba DM, Weingart JD, Wolinsky JP, Ye X, Oba-Shinjo SM, Marie SK, Holdhoff M, Agrawal N, Diaz LA Jr, Papadopoulos N, Kinzler KW, Vogelstein B, Bettegowda C.  Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord. Proc Natl Acad Sci U S A. 2015;112(31):9704-9

Honors

• David Isreal Macht Research Award, Johns Hopkins University School of Medicine (2019)
• Young Investigator Award, ASCO/Conquer Cancer Foundation (2023)
• Young Investigator Award, NCCN (2023)
• V Scholar Award (2024)