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Yu-Hsiang Hsieh

Yu-Hsiang Hsieh, MS, PhD

Highlights

Languages

  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Yu-Hsiang Hsieh

Primary Academic Title

Associate Professor of Emergency Medicine

Background

Dr. Hsieh is an associate professor in the department of emergency medicine. He, training in infectious diseases epidemiology, has extensive experience in infectious diseases diagnostics, HIV/sexually transmitted infection screening, epidemiology, and biostatistical data analysis. For the past 20 years he has been a collaborator on many projects conducted by the Division of Infectious Diseases at The Johns Hopkins University. Dr. Hsieh has served as a PI and Co-PI of NIH- and federal-funded grants for the past 17 years.

Dr. Hsieh has extensive expertise in epidemiology and biostatistics, especially in the field of HIV and sexually transmitted infections (STIs) in unfranchised and vulnerable populations. He translates his skills to focused studies in acute aspects of HIV, STIs and other infectious diseases which are commonly presented to acute care settings. Dr. Hsieh and his colleagues built and implemented an emergency department (ED)-based HIV testing and linkage-to-care (LTC) program at Johns Hopkins Hospital in 2005 and HCV program in 2015 and is currently the co-PI of both programs. Dr. Hsieh’s scientific work has identified the gaps of the ED-based HIV and HCV screening and LTC program, resulting in improved understanding of national and local trends in ED-based HIV and HCV testing, as well as epidemiological studies, through critical analysis of a national representative database and local seroepidemiological studies. Through these works, Dr. Hsieh built the first HIV Care Continuum for ED HIV-infected population and quantified gaps in HIV diagnosis and care. Dr. Hsieh and his colleagues at JHU have initiated an ED HIV PrEP referral program since 2018 and piloted an ED same day PrEP program in 2022.

Since joining the department in 2005, Dr. Hsieh began building his research career, translating his skills in epidemiology and biostatistics to focused studies in acute aspects of HIV, sexually transmitted infections and other infectious diseases which are commonly presented to emergency or acute care settings, as well as studies in disaster medicine and preparedness. He is an author of 207 peer-review articles and over 300 conference abstracts. He has served as an invited panelist in several national conferences, including the Forum for Collaborative HIV Research, National Viral Hepatitis Roundtable, and National Minority AIDS Conference and invited reviewer for over 50 peer-reviewed journals including New England Journal of Medicine, Lancet HIV, and PLoS Medicine as well as key Emergency Medicine journals e.g. Academic Emergency Medicine, American Journal of Emergency Medicine, Western Journal of Emergency Medicine, Emergency Medicine International, BMC Emergency Medicine, and International Journal of Emergency Medicine.

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Research Interests

Adherence of ED management and practices to ACEP, CDC, or other guidance, Cost-effectiveness of ED-based HIV testing program using agent-based modeling approach, Epidemiology of non-infectious diseases in ED or disaster settings, Infectious diseases epidemiology (Trends, Risk Factors, Prevention, and Outcomes) in ED settings and ED management of patients with infectious diseases

Research Summary

Dr. Hsieh is the epidemiologist/statistician in the Department of Emergency Medicine with whom we work closely on other projects. Dr. Hsieh also translates his skills to focused studies in acute aspects of HIV, STIs and other infectious diseases which are commonly presented to acute care settings. Dr. Hsieh and his colleagues built and implemented an emergency department (ED)-based HIV testing and linkage-to-care (LTC) program at Johns Hopkins Hospital in 2005 and HCV program in 2015 and is currently the co-PI of both programs. Dr. Hsieh’s scientific work has identified the gaps of the ED-based HIV and HCV screening and LTC program, resulting in improved understanding of national and local trends in ED-based HIV and HCV testing, as well as epidemiological studies, through critical analysis of a national representative database and local seroepidemiological studies. Through these works, Dr. Hsieh built the first HIV Care Continuum for ED HIV-infected population and quantified gaps in HIV diagnosis and care. Dr. Hsieh and his colleagues at JHU have initiated an ED HIV PrEP referral program since 2018 and piloted an ED same day PrEP program in 2022. 

Dr. Hsieh has particular expertise in evaluations of novel diagnostic assays in acute care setting as well as study design, participant enrollment, user’s feedback survey, quantitative and qualitative statistical data analysis in performance evaluation studies, especially in point-of-care assay industry and end-user needs assessment and performance and validation of novel diagnostic assays in the field of infectious disease screening programs and acute and indolent infectious diseases in the acute care setting.

Selected Publications

  • Haukoos JS, Lyons MS, White DA, Hsieh Y-H, Rothman RE. Acute HIV Infection and Implications of 4th Generation HIV Screening in Emergency Departments. Annals of Emergency Medicine 2014 64:547-51 (Editorial).

  • Hsieh Y-H, Gauvey-Kern M, Peterson S, Woodfield A, Deruggiero K, Gaydos CA, Rothman RE. Novel Emergency Department Registration Kiosk for HIV Screening Increases Engagement of High Risk Patients. Journal of Telemedicine and Telecare 2014 20:454-9.

  • Hsieh Y-H, Haukoos JS, Rothman RE. Validation of an Abbreviated Version of the Denver HIV Risk Score for Prediction of HIV Infection in an Urban Emergency Department. American Journal of Emergency Medicine 2014 32:775-9.

  • Hsieh Y-H, Kelen GD, Laeyendecker OB, Kraus CK, Quinn TC, Rothman RE. HIV Care Continuum for HIV-Infected Emergency Department Patients in an Inner-City Academic ED. Annals of Emergency Medicine 2015 66:69-78.

  • Rothman RE, Saheed M, Hsieh Y-H. Infectious disease/CDC update. Detection of acute HIV infection in two evaluations of a new HIV diagnostic testing algorithm--United States, 2011-2013. New HIV Technology and Algorithms. Closing Some Windows; Opening Others. Annals of Emergency Medicine 2014 63:56-60 (Editorial).

Honors

  • Co-Investigator: "Using Kiosks for HIV Point-of-Care Testing in the Emergency Department"., The Gilead Foundation
  • Co-Investigator: "Center for Point-of-Care Technologies Research for Sexually Transmitted Diseases"., National Institute of Health
  • Co-Investigator: "The National Center for Preparedness and Catastrophic Event Response (PACER) Clinical Utility of Preemptive Surge Measures Enacted as a Result of Conventional and Internet-Based Influenza Surveillance"., US Department of Homeland Security

Expertise

Education

  • Johns Hopkins Bloomberg School of Public Health, Ph.D., 1998
  • National Taiwan University, M.S., 1993