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William Sharfman

William Sharfman, MD

Cutaneous (Skin) Medical OncologyMedical Oncology

Accepting New Patients

Highlights

Age Groups Seen

  • Young Adult 18-25
  • Adult 26-64
  • Older Adult 65+

Languages

  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About William Sharfman

Professional Titles

  • Director, Cutaneous Oncology
  • Clinical Co-Director for Oncology, Johns Hopkins Melanoma Program
  • Mary Jo Rogers Professor of Cancer Immunology and Melanoma Research

Primary Academic Title

Associate Professor of Oncology

Johns Hopkins Physician

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Background

Dr. William H. Sharfman is an associate professor of oncology and dermatology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include cutaneous oncology, dermatology and immunotherapy. He helped create the well-established Melanoma Program at the Johns Hopkins Kimmel Cancer Center in 1994. Dr. Sharfman serves as the director of cutaneous oncology and clinical co-director for oncology at the Johns Hopkins Melanoma Program.

He earned his M.D. from the University of Toledo College of Medicine. He completed his residency at Cleveland Clinic and performed a fellowship in hematology and oncology at Cleveland Clinic.

Dr. Sharfman's research interests include novel therapies for high risk and advanced melanoma patients.

Find a Clinical Trial

View all trials by this principal investigator.

Recent News Articles and Media Coverage

Additional Academic Titles

Associate Professor of Dermatology

Research Interests

GI Cancers, Lung Cancer, Novel therapies for high risk and advanced melanoma patients

Research Summary

Dr. Sharfman’s research focuses on melanoma, including novel therapies for advanced melanoma patients.

Selected Publications

  • Brahmer, J.R.; Drake, C.G.; Wollner, I.; Powderly, J.D.; Picus, J.; Sharfman, W.H.; Stankevich, E.; Pons, A.; Salay, T.M.; McMiller, T.L.; Gilson, M.M.; Wang, C.; Selby, M.; Taube, J.M.; Anders, R.; Chen, L.; Korman, A.J.; Pardoll, D.M.; Lowy, I.; Topalian, S.L. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol. 2010 Jul 1;28(19):3167-3175.

  • Lange, J.R.; Fecher, L.; Sharfman, W.H.; Alani, R.M.; Mikkilineni, R.; Topalian, S.L.; Balch, C.M. Melanoma. In: Abeloff MD, A.J., Niederhuber JE, Kastan MB, McKenna WG editor. 4th ed, Abeloffs Clinical Oncology. Philadelphia: Elsevier Inc.; 2008. p. 1229-1252.

Lectures & Presentations

Skin Cancer 101 with an Emphasis on Melanoma, http://bit.ly/MelanomaWebinarVideo

Locations

  1. Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
    • 10803 Falls Road, Pavilion III STE 1500, Lutherville, MD 21093
    • Get Directions
  2. Skip Viragh Outpatient Cancer Center
    • 201 North Broadway Street, Viragh BLDG 5th FL, Baltimore, MD 21287
    • Get Directions

Expertise

Education

  • Fellowship: Cleveland Clinic, Hematology and Oncology, 1989
  • Residency: Cleveland Clinic, Internal Medicine, 1985
  • Medical Education: University of Toledo College of Medicine, MD, 1982

Board Certifications

  • Hematology: American Board of Internal Medicine, 1992
  • Medical Oncology: American Board of Internal Medicine, 1989

Insurance

Please contact the location directly to confirm your health plan is accepted.
Search plans
  • Aetna
  • CareFirst
  • Cigna
  • First Health
  • Geisinger Health Plan
  • HealthSmart/Accel
  • Johns Hopkins Health Plans
  • MultiPlan
  • Pennsylvania's Preferred Health Networks (PPHN)
  • Point Comfort Underwriters
  • Private Healthcare Systems (PHCS)
  • Veteran Affairs Community Care Network (Optum-VACCN)

Ratings & Reviews

5 out of 5

322 ratings, 124 reviews

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Overall Rating by Patient
Provider Listened Carefully
Provider Explained Things Clearly
Provider Knew Medical History
Provider Showed Respect
Provider Spent Enough Time
Search reviews
    5 out of 5 stars
    Reviewed on 3/20/2026

    Very attentive

    5 out of 5 stars
    Reviewed on 3/19/2026

    Dr. Sharfman is efficient and understanding.

    5 out of 5 stars
    Reviewed on 3/18/2026

    Dr. Sharfman seems to genuinely care very smart.

    5 out of 5 stars
    Reviewed on 3/11/2026

    Dr. Sharfman is an expert oncologist and verrry professional.

    5 out of 5 stars
    Reviewed on 3/10/2026

    Very good Doctor

    5 out of 5 stars
    Reviewed on 3/10/2026

    Dr. Sharfman is an empathetic and knowledgeable provider. He is easy to talk to and easy to reach!

    5 out of 5 stars
    Reviewed on 3/9/2026

    PROVIDER Was generous with his time and also spent time with my family.

    5 out of 5 stars
    Reviewed on 3/3/2026

    Dr Sharfman is a caring, professional provider. He has been very helpful in my melanoma surgery and treatment.

    5 out of 5 stars
    Reviewed on 2/25/2026

    Couldn't have a better cancer doctor

    5 out of 5 stars
    Reviewed on 2/19/2026

    Wonderful

    5 out of 5 stars
    Reviewed on 2/18/2026

    Personable yet professional.

    5 out of 5 stars
    Reviewed on 2/16/2026

    Dr Sharfman is so knowledgeable about melanoma. I trust his opinion!

    5 out of 5 stars
    Reviewed on 2/12/2026

    The best!!

    5 out of 5 stars
    Reviewed on 2/11/2026

    Dr Sharfman is the best. His ability to determine the best care plan for my metastatic melanoma gives me confidence and reassurance.

    5 out of 5 stars
    Reviewed on 2/10/2026

    Professional, caring, and knowledgeable.

    5 out of 5 stars
    Reviewed on 2/9/2026

    Dr, Sharfman was very thorough and clear in explaining my plan for immunotherapy going forward. I had brought a large list of questions . He answered most of those without me needing to ask. All explanations were clear and understandable.

    5 out of 5 stars
    Reviewed on 2/5/2026

    Dr. Sharfman made me feel very comfortable and confident in his evaluation and possible future treatments.

    5 out of 5 stars
    Reviewed on 2/4/2026

    Very capable and helpful.

    5 out of 5 stars
    Reviewed on 2/2/2026

    Outstanding

    5 out of 5 stars
    Reviewed on 1/29/2026

    Dr. Sharfman is an empathetic physician who inspires confidence in myself for the results he provides after the test (scan) is completed.

    5 out of 5 stars
    Reviewed on 1/28/2026

    Wonderful doctor.

    5 out of 5 stars
    Reviewed on 1/28/2026

    Excellent

    5 out of 5 stars
    Reviewed on 1/22/2026

    Dr Sharfman is the best. he is kind, informative, and encouraging, and I have them upmost respect for his opinions.

    5 out of 5 stars
    Reviewed on 1/22/2026

    Dr. Sharfman seems to be extremely knowledgeable about what he does and put us at ease from the start.

    5 out of 5 stars
    Reviewed on 1/20/2026

    Dr. Sharfman is wonderful! He is patient, caring, and very knowledgeable.

    5 out of 5 stars
    Reviewed on 1/16/2026

    I love Dr Sharfman. He's caring. It's a scary time & he is always helpful

    5 out of 5 stars
    Reviewed on 1/15/2026

    Dr. Sharfman is patient and has a good clinical plan for me.

    5 out of 5 stars
    Reviewed on 1/13/2026

    Very happy with the treatment that I receive from Dr. Sharfman.

    5 out of 5 stars
    Reviewed on 1/12/2026

    Very caring and compassionate.

    5 out of 5 stars
    Reviewed on 1/9/2026

    Excellent

    5 out of 5 stars
    Reviewed on 1/8/2026

    Dr Sharfman is very thorough and helpful.

    5 out of 5 stars
    Reviewed on 1/7/2026

    Dr. Sharfman is so helpful in guiding me through this cancer process. I appreciate his knowledge and expertise.

    5 out of 5 stars
    Reviewed on 1/2/2026

    Dr Sharfman is the consummate professional

    5 out of 5 stars
    Reviewed on 12/30/2025

    Requested an ultrasound of leg to check for blood clots.

    5 out of 5 stars
    Reviewed on 12/22/2025

    Always pleasant and competent. Questions always anticipated or answered

    5 out of 5 stars
    Reviewed on 12/16/2025

    Dr. Sharfman has been my oncologist for over 9 years and I couldn't be more pleased with the care he gives.

    5 out of 5 stars
    Reviewed on 12/16/2025

    Dr Sharfman is one of the top in the country for Melanoma. Fortunate to be able to see him.

    5 out of 5 stars
    Reviewed on 12/11/2025

    Verry good in all areas on every visit.

    5 out of 5 stars
    Reviewed on 12/4/2025

    Provided good information and options.

    5 out of 5 stars
    Reviewed on 12/3/2025

    I have been a patient of Dr Sharfman for nine years. He is an exceptional physician in every way.

    5 out of 5 stars
    Reviewed on 12/2/2025

    Dr. Sharfman is excellent! Very professional & thorough!

    5 out of 5 stars
    Reviewed on 11/26/2025

    Dr Sharfman is excellent and caring.

    5 out of 5 stars
    Reviewed on 11/25/2025

    Very happy with care provided with Dr. Sharfman.

    5 out of 5 stars
    Reviewed on 11/24/2025

    My provider has been working with me for almost 10 years. He's very sensitive to the condition that he cured and about my personal well-being. I feel the same about him.

    5 out of 5 stars
    Reviewed on 11/24/2025

    Dr. Sharfman is a tremendous physician who cares about his patients, prepares well for appointments, and provides excellent treatment plans.

    5 out of 5 stars
    Reviewed on 11/20/2025

    Dr. Sharfman is the best. When I arrived for my appointment he had already consulted with other specialists I will need to see and had shared MRI results. A clear plan for my treatment was in place and he discussed it with me in detail, and he considered my choice in the treatment plan. No one wants to navigate a cancer journey, but Dr. Sharfman removes all unnecessary anxiety through his extremely calm approach and his wealth of knowledge.

    5 out of 5 stars
    Reviewed on 11/20/2025

    Dr Sharfman is the best of the best, He took the time necessary to understand my needs and thoroughly explained answers in response to my questions.

    5 out of 5 stars
    Reviewed on 11/20/2025

    Great bedside manner.

    5 out of 5 stars
    Reviewed on 11/19/2025

    Excellent doctor! He listens and reacts! Highly recommend.

    5 out of 5 stars
    Reviewed on 11/19/2025

    Dr. Sharfman is the best! Always listens, I am grateful to have him as my oncologist.

    5 out of 5 stars
    Reviewed on 11/19/2025

    Dr. Sharfman is very thorough and helpful.

    5 out of 5 stars
    Reviewed on 11/19/2025

    I feel he is the best for my condition

    5 out of 5 stars
    Reviewed on 11/13/2025

    Set up an immediate treatment plan for a new cancer I'm experiencing. The doctors expertise comforted me in this new territory

    5 out of 5 stars
    Reviewed on 11/13/2025

    Oncologist Doctor William H. Sharfman was very caring, thorough, and fantastic during my visit on 11/13/2025!

    5 out of 5 stars
    Reviewed on 11/12/2025

    Very good,!

    5 out of 5 stars
    Reviewed on 11/12/2025

    I had a very kind and complete medical experience .

    5 out of 5 stars
    Reviewed on 11/10/2025

    Outstanding in every way. Compassionate, knowledgeable, and respectful.

    5 out of 5 stars
    Reviewed on 11/4/2025

    I see Dr. Sharfman for an annual check after interferon treatment for invasive melanoma almost 20 years ago.He state up to date on my subsequent skin cancer issues.

    5 out of 5 stars
    Reviewed on 10/23/2025

    Very professional and knowledgable

    5 out of 5 stars
    Reviewed on 10/21/2025

    Scheduling was efficient. Records were obtained from our referring provider. Everyone is courteous, personable. Dr. Sharfman is exceptional. Kind, thoughtful, thorough. We feel very fortunate to have connected with him.

    5 out of 5 stars
    Reviewed on 10/21/2025

    Dr Sharfman went over & above to get me the medicine I needed to resolve my issue

    5 out of 5 stars
    Reviewed on 10/20/2025

    Dr, Sharfman is a terrific doctor. He Is very attentive and never rushes appointments. I have felt very cared for and about throughout diagnosis, treatment and follow-up check-ups.

    5 out of 5 stars
    Reviewed on 10/16/2025

    Dr Sharfman and everyone at the facility showed me the utmost care and professionalism during my visit.

    5 out of 5 stars
    Reviewed on 10/13/2025

    Dr. Sharfman is wonderful and I trust him explicitly!

    5 out of 5 stars
    Reviewed on 10/13/2025

    Outstanding professional

    5 out of 5 stars
    Reviewed on 10/3/2025

    All good

    5 out of 5 stars
    Reviewed on 9/30/2025

    Dr. Sharfman always takes time to listen to and address my concerns. I never feel rushed or dismissed. The nurse, [staff], always follows up to ensure I understand and that my needs are met. They are an excellent team.

    5 out of 5 stars
    Reviewed on 9/29/2025

    Hopkins has provided the best care that I have received. First rate in all areas.

    5 out of 5 stars
    Reviewed on 9/26/2025

    Excellent care

    5 out of 5 stars
    Reviewed on 9/22/2025

    Dr. Sharfman is simply amazing. He listens to my concerns and provides excellent care strategies.

    5 out of 5 stars
    Reviewed on 9/18/2025

    Dr. Sharfman is upfront and honest about my health and concerns he has. I am completely confident in his ability to provide the care I need.

    5 out of 5 stars
    Reviewed on 9/18/2025

    Always have excellent care from Hopkins

    5 out of 5 stars
    Reviewed on 9/16/2025

    Dr. Sharfman, not only is he tops in his field', he is a kind and thoughtful man. The first thing he asked me was ""How are your new twin granddaughters?"" We shared personal experiences before he explained the details of my scans and checkup.

    5 out of 5 stars
    Reviewed on 9/16/2025

    Dr Sharfman is a very knowledge, class act. I'm thrilled to have him leading my care.

    5 out of 5 stars
    Reviewed on 9/15/2025

    Professional, courteous and always concerned about my health.

    5 out of 5 stars
    Reviewed on 9/10/2025

    I have been seeing Dr. Sharfman for 25 years since my original melanoma diagnosis in 2000 and he is one of the most excellent doctors I I have known. He is steady, thorough, compassionate, skilled. I am privileged to have been cared for by him for so long.

    5 out of 5 stars
    Reviewed on 9/9/2025

    I have been a patient of Dr. Sharfman for quite a few years now. He is compassionate, considerate, thoughtful and professional in every way. I appreciate him immensely.

    5 out of 5 stars
    Reviewed on 9/8/2025

    Dr. Sharfman saved my life and I will NEVER loose sight of this. Dr. Sharfman is one of the best Dr.'s I've had. His gentle nature, vast unbelievable knowledge of MCC always gave me hope. He truly cares about his patients and has always listened to my concerns and answered to the best of his ability. He has a way of making you feel at ease. He's just a wonderful man.

    5 out of 5 stars
    Reviewed on 9/8/2025

    Doctor Scharfman is wonderful, I am grateful he is my provider.

    5 out of 5 stars
    Reviewed on 9/4/2025

    Very knowledgeable about my condition. Explained the options available for treatment. Great ""bedside"" manner! Instills much confidence.

    5 out of 5 stars
    Reviewed on 9/4/2025

    Dr. Sharfman is the best doctor I have ever had. He is caring and attentive and gives nothing but the best possible service

    5 out of 5 stars
    Reviewed on 9/4/2025

    Doctor was well informed & gave excellent advise

    5 out of 5 stars
    Reviewed on 9/3/2025

    Dr Sharfman is so attentive, has genuine concern for my health,care,& comfort,I feel completely at ease with him,& have complete trust in him.

    5 out of 5 stars
    Reviewed on 9/2/2025

    Dr. Sharfman is knowledgeable, personable & professional. I trust his advice totally.

    5 out of 5 stars
    Reviewed on 8/26/2025

    Very glad I have Dr. Sharfman as my Doctor.

    5 out of 5 stars
    Reviewed on 8/25/2025

    Excellent care

    5 out of 5 stars
    Reviewed on 8/14/2025

    Excellent!!

    5 out of 5 stars
    Reviewed on 8/7/2025

    Dr Sharfman was terrific. Very thorough and thoughtful about his diagnosis and treatment options. We drove 3 hrs to see him and he was a godsend. We can't say enough great things about this Dr. We felt so much better upon leaving. Thank you.

    5 out of 5 stars
    Reviewed on 8/6/2025

    Dr Sharfman was very helpful in providing a second opinion. Very knowledge in the field I was seeking help in.

    5 out of 5 stars
    Reviewed on 8/4/2025

    Excellent

    5 out of 5 stars
    Reviewed on 7/21/2025

    I Have all of the confidence in the world In Dr Sharfman

    5 out of 5 stars
    Reviewed on 7/21/2025

    Always great to see him, very personable.

    5 out of 5 stars
    Reviewed on 7/16/2025

    Dr. Sharfman is the best. He always explains things, is endlessly encouraging and positive, and instills me with the confidence necessary to deal with whatever needs to be faced. Can't imagine my cancer journey with anyone else. The added bonus is that thanks to his skill and Hopkins' resources, my cancer has been crushed.

    5 out of 5 stars
    Reviewed on 7/15/2025

    Dr. Sharfman is always on top of everything. He is an excellent provider. Always thorough and compassionate.

    5 out of 5 stars
    Reviewed on 7/15/2025

    All of my experiences with Johns Hopkins have been professional and caring

    5 out of 5 stars
    Reviewed on 7/15/2025

    I have been going to Dr. Sharfman for 10 years. I wouldn't want to go anywhere else. He's very knowledgeable and listens, explains any questions throughly.

    5 out of 5 stars
    Reviewed on 7/14/2025

    Dr. Sharfman continues to provide the most comprehensive treatment for me. I am quite certain that he has saved my life and provided me with extended time I most likely would not have had but for his involvement!

    5 out of 5 stars
    Reviewed on 7/10/2025

    Cordial, confident, informative

    5 out of 5 stars
    Reviewed on 7/10/2025

    Excellent visit

    5 out of 5 stars
    Reviewed on 7/3/2025

    Dr. Sharfman understood my concerns and was very helpful. I am very glad that I chose this facility and Dr.

    5 out of 5 stars
    Reviewed on 7/2/2025

    Great

    5 out of 5 stars
    Reviewed on 6/26/2025

    Dr. Sharfman is a consummate, knowledgeable professional who is friendly and caring.

    5 out of 5 stars
    Reviewed on 6/26/2025

    Dr. William Sharfman is the best doctor. He is very knowledgeable, caring and understanding. He listens to what I am concerned about with my health. I can't thank him enough for coordinating the doctors I needed to see eleven years ago, when I was going through melanoma, and my Pet CT scan gave a false positive. Dr. Sharfman is Excellent.

    5 out of 5 stars
    Reviewed on 6/26/2025

    Wonderful

    5 out of 5 stars
    Reviewed on 6/23/2025

    Dr Sharfman is engaged in oncology research which I believe saved my life I am grateful that he took me on as a patient.

    5 out of 5 stars
    Reviewed on 6/17/2025

    Outstanding, caring doctor. He helped me with a complex 2nd opinion.

    5 out of 5 stars
    Reviewed on 6/17/2025

    Johns Hopkins had the best providers in all fields. Never had a bad experience in all the 12 years I have gone there.

    5 out of 5 stars
    Reviewed on 6/16/2025

    Very happy and glad Dr Sharfman is my oncologist

    5 out of 5 stars
    Reviewed on 6/12/2025

    Dr. Sharfman is a very kind and caring man.

    5 out of 5 stars
    Reviewed on 6/10/2025

    He saved my life, emotionally and physically

    5 out of 5 stars
    Reviewed on 6/9/2025

    Professional, polite

    5 out of 5 stars
    Reviewed on 6/9/2025

    I feel as though Dr Sharfman saved my life he is a great Dr

    5 out of 5 stars
    Reviewed on 6/9/2025

    Excellent communication skills. Compassionate and caring, Trust him completely.

    5 out of 5 stars
    Reviewed on 6/9/2025

    They are the best!!

    5 out of 5 stars
    Reviewed on 6/5/2025

    He's wonderful

    5 out of 5 stars
    Reviewed on 5/22/2025

    Good quality check up following my lab work and CT scan.

    5 out of 5 stars
    Reviewed on 5/22/2025

    First time appointment with Dr Sharfman. He is a delight and so pleased he was recommended by [staff].

    5 out of 5 stars
    Reviewed on 5/19/2025

    Dr. Sharfman listened to my concerns & came up with ideas to tackle the problem

    5 out of 5 stars
    Reviewed on 5/19/2025

    Dr. Sharfman is an incredible doctor and his Team as well.

    5 out of 5 stars
    Reviewed on 5/14/2025

    Dr Sharfman is an excellent provider. He is very concerned with my comfort in everyday. I trust him with my health care.

    5 out of 5 stars
    Reviewed on 5/14/2025

    Dr. Sharfman deliveries outstanding patient care in terms I can understand. .

    5 out of 5 stars
    Reviewed on 5/14/2025

    Dr. Sharfman is a great doctor who is easy to talk to and answers all of my questions.

    5 out of 5 stars
    Reviewed on 4/22/2025

    Best Melanoma doctor in the country, very knowledgeable, significant experience. AND good communication and care

    5 out of 5 stars
    Reviewed on 4/16/2025

    Excellent, reassuring appointment.