Stephen Mathai, MD, MHS

Professional Titles

• Director, Inpatient Pulmonary Service, Johns Hopkins Hospital
• Co-Director, Ann Dana Kusch Multidisciplinary Program for Interstitial Lung Disease and Pulmonary Hypertension Research

Primary Academic Title

Associate Professor of Medicine

Background

Centers and Institutes

• Heart and Vascular Institute
• Scleroderma Center

Find a Clinical Trial

Research Interests

Idiopathic pulmonary fibrosis, Pulmonary complications of connective tissue disease, Pulmonary hypertension, Scleroderma-associated pulmonary hypertension

Lab Website

Stephen Mathai Lab

• The Stephen Mathai Lab focuses its research on pulmonary medicine. We're particularly interested in scleroderma-associated pulmonary hypertension, pulmonary complications of connective tissue disease, idiopathic pulmonary fibrosis and pulmonary hypertension.

PubMed - Publications

http://www.ncbi.nlm.nih.gov/pubmed?dispmax=20&pmfilter_EDatLimit=added+to+PubMed+in+the+last+0+i&cmd_current=Limits&orig_cmd=Search&term=MATHAI+SC%5BAuthor+Name%5D&doptcmdl=DocSum

Selected Publications

• Bonner N, Abetz L, Meunier J, Sikirica M, Mathai SC. Development and validation of the living with pulmonary hypertension questionnaire in pulmonary arterial hypertension patients. Health Qual Life Outcomes. 2013 Oct 3;11:161. doi: 10.1186/1477-7525-11-161. PMID: 24088389 

• Bourji KI, Khair RM, Damico RL, Kolb TM, Mathai SC, Hassoun PM. “Vascular receptor autoantibodies in pulmonary arterial hypertension.” Am J Respir Crit Care Med. 2015 Mar 1;191(5):602. doi: 10.1164/rccm.201412-2267LE.

• Chin K, Mathai SC. “Exercise echocardiography in connective tissue disease.” J Am Coll Cardiol. 2015 Jul 28;66(4):385-7. doi: 10.1016/j.jacc.2015.05.038. 

• Damico R, Kolb TM, Valera L, Wang L, Housten T, Tedford RJ, Kass DA, Rafaels N, Gao L, Barnes KC, Benza RL, Rand JL, Hamid R, Loyd JE, Robbins IM, Hemnes AR, Chung WK, Austin ED, Drummond MB, Mathai SC, Hassoun PM. “Serum endostatin is a genetically determined predictor of survival in pulmonary arterial hypertension.” Am J Respir Crit Care Med. 2015 Jan 15;191(2):208-18. doi: 10.1164/rccm.201409-1742OC.

• Dezube R, Terry P, Akulian J, Mathai SC, Boyle M, Khasab T, Yarmus L. Chronic expanding hematoma of the lung. Am J Respir Crit Care Med. 2013 Dec 1;188(11):e71. doi: 10.1164/rccm.201304-0723IM. No abstract available. PMID: 24289786

• Kelemen BW, Mathai SC, Tedford RJ, Damico RL, Corona-Villalobos C, Kolb TM, Chaisson NF, Harris TH, Zimmerman SL, Kamel IR, Kass DA, Hassoun PM. “Right ventricular remodeling in idiopathic and scleroderma-associated pulmonary arterial hypertension: two distinct phenotypes.” Pulm Circ. 2015 Jun;5(2):327-34. doi: 10.1086/680356.

• Khanna D, Gladue H, Channick R, Chung L, Distler O, Furst DE, Hachulla E, Humbert M, Langleben D, Mathai SC, Saggar R, Visovatti S, Altorok N, Townsend W, FitzGerald J, McLaughlin VV. Recommendations for screening and detection of connective tissue disease-associated pulmonary arterial hypertension. Arthritis Rheum. 2013 Dec;65(12):3194-201. doi: 10.1002/art.38172. PMID: 24022584

• Mathai SC, Hassoun PM. Drs. Mathai and Hassoun reply. J Rheumatol. 2013 Jan;40(1):91. No abstract available. PMID: 23401876 

• Mathai SC, Wise RA, Puhan MA, Lam D. Reply from the authors. Am J Respir Crit Care Med. 2013 Mar 15;187(6):659. No abstract available. PMID: 23614142

• Mathai SC. A look to the past, present, and future of pulmonary hypertension. Int J Clin Pract Suppl. 2013 May;(179):1. doi: 10.1111/ijcp.12173. No abstract available. PMID: 23578067

• Mathai SC. Solvitur ambulando…or maybe not? Chest. 2013 Feb 1;143(2):285-7. doi: 10.1378/chest.12-1819. No abstract available. PMID: 23381304

• Matura LA, Ventetuolo CE, Palevsky HI, Lederer DJ, Horn EM, Mathai SC, Pinder D, Archer-Chicko C, Bagiella E, Roberts KE, Tracy RP, Hassoun PM, Girgis RE, Kawut SM. “Interleukin-6 and tumor necrosis factor-α are associated with quality of life-related symptoms in pulmonary arterial hypertension.” Ann Am Thorac Soc. 2015 Mar;12(3):370-5. doi: 10.1513/AnnalsATS.201410-463OC. PMID: 25615959

• Shehata ML, Harouni AA, Skrok J, Basha TA, Boyce D, Lechtzin N, Mathai SC, Girgis R, Osman NF, Lima JA, Bluemke DA, Hassoun PM, Vogel-Claussen J. Regional and global biventricular function in pulmonary arterial hypertension: a cardiac MR imaging study. Radiology. 2013 Jan;266(1):114-22. doi: 10.1148/radiol.12111599. Epub 2012 Nov 14. PMID: 23151825

• Tedford RJ, Mudd JO, Girgis RE, Mathai SC, Zaiman AL, Housten-Harris T, Boyce D, Kelemen BW,  Bacher AC, Shah AA, Hummers LK, Wigley FM, Russell SD, Saggar R, Saggar R, Maughan WL, Hassoun PM, Kass DA. Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension. Circ Heart Fail. 2013 Sep 1;6(5):953-63. PMID: 23797369

• Yarmus LB, Akulian JA, Gilbert C, Mathai SC, Sathiyamoorthy S, Sahetya S, Harris K, Gillespie C, Haas A, Feller-Kopman D, Sterman D, Lee HJ. Comparison of moderate versus deep sedation for endobronchial ultrasound transbronchial needle aspiration. Ann Am Thorac Soc. 2013 Apr;10(2):121-6. doi: 10.1513/AnnalsATS.201209-074OC. PMID: 23607840

Honors

Frederick L. Brancati Award for Mentorship

Professional Activities

• Patient Centered Outcomes Research Institute, Rare Disease Advisory Panel
• Pulmonary Hypertension Association, Scientific Leadership Council
• Pulmonary Vascular Disease Network, American College of Chest Physicians, Chair