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Ross C. Donehower

Ross C. Donehower, MD

Medical Oncology

Accepting New Patients

Highlights

Age Groups Seen

  • Young Adult 18-25
  • Adult 26-64
  • Older Adult 65+

Languages

  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Ross C. Donehower

Professional Titles

  • Director, Medical Oncology/Hematology Fellowship Training Program
  • Director, Division of Medical Oncology
  • Virginia and D.K. Ludwig Professor in Clinical Investigation of Cancer

Primary Academic Title

Professor of Oncology

Johns Hopkins Physician

Logo for Johns Hopkins Physician

Background

Dr. Ross C. Donehower is an oncologist in the Baltimore area, caring for patients with gastrointestinal cancers. He was part of the team that developed premedications that allowed paclitaxel — a chemotherapy medication now used to treat several types of cancers — to be safely given to patients. The Virginia and D.K. Ludwig Professor in Clinical Investigation of Cancer, he serves as the director of the Hematology & Medical Oncology Fellowship Program and director of the Division of Medical Oncology at the Johns Hopkins School of Medicine.

Dr. Donehower received his undergraduate degree from Hamline University and earned his M.D. from the University of Minnesota. He completed his residency at The Johns Hopkins Hospital. Dr. Donehower joined the Johns Hopkins faculty in 1980.

Prior to joining Johns Hopkins, Dr. Donehower was a surgeon with the U.S. Public Health Service and a clinical associate of the medicine branch and clinical pharmacology branch at the National Cancer Institute.

His research interests include gastrointestinal cancers, new anticancer drug development and pharmacology.

Dr. Donehower serves on the editorial boards of numerous scholarly journals, including the International Journal of Oncology. He has been recognized by the American Society of Clinical Oncology with a 2017 Excellence in Teaching Award. He is a member of several professional organizations, including the American College of Physicians, the American Society of Clinical Oncology and the American Association for Cancer Research.

Additional Academic Titles

Professor of Medicine

Research Interests

Gastrointestinal Cancers, New Anticancer Drug Development, Pharmacology

Selected Publications

  • Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Greten TF, Duggy AG, Ciombor KK, Eyring AD, Lam BH, Joe A, Kang SP, Holdhofff M, Danilova L, Cope L, Meyer C, Zhou S, Goldberg RM, Armstrong DK, Bever KM, Fader AN, Taub J, Housseau F, Spetzler D, Xiao N, Pardoll DM, Papadopoulos N, Kinzler KW Exhleman JR, Vogelstein B, Anders RA, Diaz LA Jr. “Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.” Science. 2017;357(6349):409-413

  • Naik RP, Marrone K, Merrill S, Donehower R, Brodsky R. “Single-board hematology fellowship track: A 10-year institutional experience.” Blood. 2018;131(4):462-464

  • Reiss KA, Rangachari D, Cosgrove D, Wilky B, Donehower R. “Growing pains: A simulation-based curriculum for improving the transition to hematology/oncology fellowship.” J Cancer Educ. 2017;32(3):496-502

  • Shrestha B, Sun Y, Faisal F, Kim V, Soares K, Blair A, Herman JM, Narang A, Dholakia AS, Rosati L, Hacker-Prietz A, Chen L, Laheru, DA, DeJesus-Acosta A, Le DT, Donehower R, Azad N, Diaz LA, Murphy A, Lee V, Fishman EK, Hruban RH, Liang T, Cameron JL, Makary M, Weiss MJ, Ahuja N, He J, Wolfgang CL, Huang CY, Zheng L. “Long-term survival benefit of upfront chemotherapy in patients with newly diagnosed borderline resectable pancreatic cancer.” Cancer Med. 2017;6(7):1552-1562

  • Yarchoan M, Myzak MC, Johnson BA 3rd, De Jesus-Acosta A, Le DT, Jaffee EM, Azad NS, Donehower RC, Zheng L, Oberstein PE, Fine RL, Laheru DA, Goggins M. “Olaparib in combination with irinotecan, cisplatin, and mitomycin C in patients with advanced pancreatic cancer.” Oncotarget. 2017 Jul 4;8(27):44073-44081

Honors

  • Excellence in Teaching Award, American Society of Clinical Oncology, 1/1/17
  • Director's Teaching Award, Johns Hopkins Cancer Center, 1/1/16
  • Member, Miller-Coulson Academy of Clinical Excellence, Johns Hopkins School of Medicine, 1/1/15

Memberships

  • American College of Physicians
  • American Society of Clinical Oncology
  • American Association for Cancer Research
  • European Society of Medical Oncology

Professional Activities

  • Clinical Cancer Research, Editorial Board, 1/1/94
  • International Journal of Oncology, Editorial Board, 1/1/02
  • Investigational New Drugs, Editorial Board, 1/1/98
  • Johns Hopkins School of Medicine, Faculty Senate, 1/1/19
  • Journal of the National Cancer Institute, Associate Editor, 1/1/94
  • The Oncologist, Associate Editor, 1/1/96

Locations

  1. Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
    • 10803 Falls Road, Pavilion III STE 1500, Lutherville, MD 21093
    • Get Directions
  2. Skip Viragh Outpatient Cancer Center
    • 201 North Broadway Street, Viragh BLDG 5th FL, Baltimore, MD 21287
    • Get Directions

Expertise

Education

  • Fellowship: National Institutes of Health, Medical Oncology, 1980
  • Residency: Johns Hopkins University School of Medicine, Internal Medicine, 1976
  • Medical Education: University of Minnesota Medical School, MD, 1974

Board Certifications

  • Medical Oncology: American Board of Internal Medicine, 1979
  • Internal Medicine: American Board of Internal Medicine, 1977

Insurance

Search plans
  • Aetna
  • CareFirst
  • Cigna
  • First Health
  • Geisinger Health Plan
  • HealthSmart/Accel
  • Johns Hopkins Health Plans
  • MultiPlan
  • Pennsylvania's Preferred Health Networks (PPHN)
  • Point Comfort Underwriters
  • Private Healthcare Systems (PHCS)
  • Veteran Affairs Community Care Network (Optum-VACCN)

Ratings & Reviews

5 out of 5

83 ratings, 46 reviews

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Search reviews
    5 out of 5 stars
    Reviewed on 4/14/2026

    Very knowledgeable and caring

    5 out of 5 stars
    Reviewed on 4/10/2026

    Exceptional preparation for the consultation with me followed by confirmation of my treatment plan and possibilities related to participation in medical trials.

    5 out of 5 stars
    Reviewed on 4/8/2026

    Dr Donehower is a great doctor. He listens, is compassionate and very knowledgeable!!

    5 out of 5 stars
    Reviewed on 4/7/2026

    Dr. Donehower was excellent. He carefully explained everything concerning my cancer and answered all my questions. He was very kind and compassionate and for the first time feel hopeful about my health. He was so wonderful my wife keeps referring to him as Dr. Marcus Welby.

    5 out of 5 stars
    Reviewed on 4/7/2026

    Dr. Donehower goes above & beyond to provide excellent care & exceeds all expectations.

    5 out of 5 stars
    Reviewed on 3/31/2026

    Excellent!

    5 out of 5 stars
    Reviewed on 3/27/2026

    Very pleased with Doctor Donehower attention to details and his positive attitude during my visit.

    5 out of 5 stars
    Reviewed on 3/25/2026

    Dr, Donehower is knowledgeable and caring.

    5 out of 5 stars
    Reviewed on 3/24/2026

    I have a great appreciation for Dr Donehower and how he has cared for me from the beginning of my visits to Hopkins

    5 out of 5 stars
    Reviewed on 2/17/2026

    Very thoughtful, throurough and listened to concerns

    5 out of 5 stars
    Reviewed on 2/17/2026

    All was great

    5 out of 5 stars
    Reviewed on 2/10/2026

    The best provider I can wish for to care and follow-up with me on my health. Thank you Dr. Donehower!

    5 out of 5 stars
    Reviewed on 2/3/2026

    Excellent

    5 out of 5 stars
    Reviewed on 2/3/2026

    My visit was a really good experience. It was very informative and professional. The person was both empathetic and knowledgeable. I was glad that I was able to have the appointment.

    5 out of 5 stars
    Reviewed on 2/3/2026

    Easy to understand

    5 out of 5 stars
    Reviewed on 2/3/2026

    Excelent

    5 out of 5 stars
    Reviewed on 1/13/2026

    Dr. Donehower is simply the best. Amazing bedside manner too.

    5 out of 5 stars
    Reviewed on 1/6/2026

    Very responsive and knowledgeable. Am grateful for the medical care.

    5 out of 5 stars
    Reviewed on 12/30/2025

    Best doctor , healer

    5 out of 5 stars
    Reviewed on 12/30/2025

    The provider was professional, compassionate, and communicative. I felt heard and supported throughout the encounter.

    5 out of 5 stars
    Reviewed on 12/12/2025

    Everyone was courteous and respectful. Everyone was wonderful and listening.

    5 out of 5 stars
    Reviewed on 12/12/2025

    He's great great great

    5 out of 5 stars
    Reviewed on 12/9/2025

    Excellent care and service

    5 out of 5 stars
    Reviewed on 12/9/2025

    Both Dr. Donehower and [staff] listened to me and had spent time reviewing my records and said they would come up with a plan after my test results were back.

    5 out of 5 stars
    Reviewed on 11/21/2025

    The best.

    5 out of 5 stars
    Reviewed on 10/29/2025

    Concerned, caring, attentive

    5 out of 5 stars
    Reviewed on 10/21/2025

    Dr. Donehower made my path through the journey of treating my illness and follow-ups as pleasant as it can be. Thank you.

    5 out of 5 stars
    Reviewed on 10/10/2025

    Outstanding.

    5 out of 5 stars
    Reviewed on 10/8/2025

    Excellent doctor

    5 out of 5 stars
    Reviewed on 10/8/2025

    Dr Donehower is a great physician. I am so pleased he is my oncologist!

    5 out of 5 stars
    Reviewed on 10/3/2025

    The doctor, his assistant and the nurse were excellent in all areas. My daughter and I were grateful to experience and learn from these superb and caring persons.

    5 out of 5 stars
    Reviewed on 9/23/2025

    Good visit

    5 out of 5 stars
    Reviewed on 9/12/2025

    Dr. Donehower is a wonderful caring doctor.

    5 out of 5 stars
    Reviewed on 9/10/2025

    Dr Donehower is a brilliant Dr. He makes sure he covers all aspect of the care and treatment needed and goes out of his way to educate me as a patient so that I understand by medical situation as well as interpret any test results. He is an amazing oncologist who demonstrates not only clinical expertise but also compassion and sincerity for his patients. He Is a example of what a great Doctor should be.

    5 out of 5 stars
    Reviewed on 9/2/2025

    What a great doctor! Excellent work!

    5 out of 5 stars
    Reviewed on 8/19/2025

    Outstanding!

    5 out of 5 stars
    Reviewed on 8/5/2025

    Easy to talk to.

    5 out of 5 stars
    Reviewed on 7/29/2025

    Dr. Donehower is always professional, courteous & kind. He is an earnest listener & responder. I have full confidence in him.

    5 out of 5 stars
    Reviewed on 7/22/2025

    Dr. Donehower has the wealth of information and care any patient would wish to have as her/his physician. Thank you JH for having him!!

    5 out of 5 stars
    Reviewed on 7/1/2025

    Thank you for your excellent customer service! The compassion, empathy and support make this challenging journey a lot easier!

    5 out of 5 stars
    Reviewed on 6/20/2025

    Dr. Was very knowledgeable and helpful

    5 out of 5 stars
    Reviewed on 5/30/2025

    Awesome

    5 out of 5 stars
    Reviewed on 5/29/2025

    Everything was so kind and helpful. Dr Ross Donehower Answered all my questions. Thank you so much.

    5 out of 5 stars
    Reviewed on 5/23/2025

    Outstanding physician care.

    5 out of 5 stars
    Reviewed on 5/21/2025

    Dr Donehower is excellent and always explains everything well.

    5 out of 5 stars
    Reviewed on 5/20/2025

    Excellent care