Peter V. Johnston, MD

Professional Titles

• Medical Director, Cardiac Catheterization Laboratory, Johns Hopkins Howard County Medical Center

Primary Academic Title

Associate Professor of Clinical Medicine

Background

Centers and Institutes

Heart and Vascular Institute

Clinical Trial Keywords

Cell therapy; Gene therapy; Interventional Cardiology

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Research Interests

Optimization of primary angioplasty for acute myocardial infarction, Stem Cell Therapy for the Heart

Lab Website

Johnston-Hwang Lab

• Development and optimization of stem cell and regenerative therapies for heart failure and myocardial infarction. CardiAMP Heart Failure Trial, Implantable Bioreactor for Prevention of Adverse Remodeling after Myocardial Infarction

PubMed - Publications

https://www.ncbi.nlm.nih.gov/myncbi/peter.johnston.4/bibliography/public/

Selected Publications

• Johnston PV, Duckers HJ, Raval AN, Cook TD, Pepine CJ.  Not all stem cells are created equal: the case for prospective assessment of stem cell potency in the CardiAMP heart failure trial. Circ Res 2018;123:944-6

• Johnston PV, Hwang CW, Bogdan V, Mills KJ, Eggan ER, Leszczynska A, Wu KC, Herzka DA, Brinker JA, Schulman SP, Banerjee M, Florea V, Natsumeda M, Tompkins B, Balkan W, Hare JM, Tomaselli GF, Weiss RG, Gerstenblith G. Intravascular stem cell bioreactor for prevention of adverse remodeling after myocardial infarction. J Am Heart Assoc, 2019;8:e012351

• Johnston PV, Sasano T, Mills K, Evers R, Lee ST, Smith RR, Lardo AC, Steenbergen C, Gerstenblith G, Lange R, Marbán E.  Engraftment, differentiation and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation. 2009;120(12):1075-83

• Hung G, Ashvetiya T, Leszczynska A, Yang W, Hwang CW, Gerstenblith G, Barth AS, Johnston PV. Paracrine-mediated rejuvenation of aged mesenchymal stem cells is associated with downregulation of the autophagy-lysosomal pathway. NPJ Aging 2022 Jul 18; 8(10)

• Makkar R, Smith RR, Cheng K, Malliaras K, Thomson LE, Berman D, Czer LS, Marbán L, Mendizabal A, Johnston PV, Russell SD, Schuleri KH, Lardo AC, Gerstenblith G, Marbán E. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet. 2012;379(9819):895-904

Patents

• Methods for Promoting Healing of Tissue, U.S. Patent #10,772,716, 9/15/20
• Cell impregnated sleeve for paracrine and other factor production, U.S. Patent #10,561,830, 2/18/20
• Cell impregnated sleeve for paracrine and other factor production, Patent #10,987,501, 4/27/21
• A Device and Method for Non-Invasive Left Ventricular End Diastolic Pressure (LVEDP) Measurement., U.S. Patent #10,729,337, 8/4/20

Honors

• Innovations in Clinical Care, 2021 Johns Hopkins Medicine Clinical Awards
• Abstract Travel Award, American Heart Association Scientific Sessions 2006, American Heart Association Council on Basic Cardiovascular Sciences, 1/1/06
• Stanley L. Blumenthal, MD Cardiology Research Award, Johns Hopkins University School of Medicine., 1/1/06
• Most Aequanimitas Intern., Osler Medical Housestaff, Johns Hopkins Hospital., 1/1/01

Memberships

• American College of Cardiology,

  FACC

• American Heart Association,

  FAHA