Nilo Azad, MD

Professional Titles

• Associate Director, Clinical Research
• Co-Leader of Cancer Genetics and Epigenetics

Primary Academic Title

Professor of Oncology

Background

Centers and Institutes

• Sidney Kimmel Comprehensive Cancer Center
• Colon Cancer Center | Johns Hopkins Kimmel Cancer Center
• Skip Viragh Center for Pancreatic Cancer
• Liver Cancer | Johns Hopkins Kimmel Cancer Center

Clinical Trial Keywords

colorectal cancer, pancreatic cancer, cholangiocarcinoma, bile duct cancer

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Research Interests

GI Cancers: Colorectal, pancreatobiliary

Google Scholar - Publications

https://scholar.google.com/citations?user=_7jVtaMAAAAJ&hl=en&oi=ao

PubMed - Publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=azad+ns

Selected Publications

• Baretti M, Danilova L, Durham JN, Betts CB, Cope L, Sidiropoulos DN, Tandurella JA, Charmsaz S, Gross N, Hernandez A, Ho WJ, Thoburn C, Walker R, Leatherman J, Mitchell S, Christmas B, Saeed A, Gaykalova DA, Yegnasubramanian S, Fertig EJ, Coussens LM, Yarchoan M, Jaffee E, Azad NS. Entinostat in combination with nivolumab in metastatic pancreatic ductal adenocarcinoma: a phase 2 clinical trial. Nat Commun. 2024 Nov 12;15(1):9801. doi:10.1038/s41467-024-52528-7. PMID: 39532835; PMCID: PMC11557583.
• Lee V, Parkinson R, Zahurak M, Cope L, Cercek A, Verheul H, Gootjes E, Lenz HJ, Iqbal S, Jones P, Baylin S, Rami V, Ahuja N, El Khoueiry A, Azad NS. A phase II study of guadecitabine combined with irinotecan vs regorafenib or TAS-102 in irinotecan-refractory metastatic colorectal cancer patients. Int J Cancer. 2024 May 15;154(10):1794-1801. doi: 10.1002/ijc.34845. Epub 2024 Feb 5. PMID:38312102.
• Baretti M, Murphy AG, Zahurak M, Gianino N, Parkinson R, Walker R, Lopez-Vidal TY, Zheng L, Rosner G, Ahuja N, Kurt S, Azad NS. A study of using epigenetic modulators to enhance response to pembrolizumab (MK-3475) in microsatellite stable advanced colorectal cancer. Clin Epigenetics. 2023 Apr 29;15(1):74. doi: 10.1186/s13148-023-01485-x. PMID: 37120591; PMCID:PMC10149019.36463226; PMCID: PMC9719150.
• Yarchoan M, Cope L, Ruggieri AN, Anders RA, Noonan AM, Goff LW, Goyal L, Lacy J, Li D, Patel AK, He AR, Abou-Alfa GK, Spencer K, Kim EJ, Davis SL, McRee AJ, Kunk PR, Goyal S, Liu Y, Dennison L, Xavier S, Mohan AA, Zhu Q, Wang-Gillam A, Poklepovic A, Chen HX, Sharon E, Lesinski GB, Azad NS. Multicenter randomized phase II trial of atezolizumab with or without cobimetinib in biliary tract cancers. J Clin Invest. 2021 Dec 15;131(24):e152670. doi: 10.1172/JCI152670.PMID: 34907910; PMCID: PMC8670844.
• Bever KM, Thomas DL 2nd, Zhang J, Diaz Rivera EA, Rosner GL, Zhu Q, Nauroth JM, Christmas B, Thompson ED, Anders RA, Judkins C, Liu M, Jaffee EM, Ahuja N, Zheng L, Azad NS. A feasibility study of combined epigenetic and vaccine therapy in advanced colorectal cancer with pharmacodynamic endpoint. Clin Epigenetics. 2021 Feb 2;13(1):25. doi: 10.1186/s13148-021-01014-8. PMID: 33531075; PMCID: PMC7856736.