Highlights
Age Groups Seen
- Infant 0-2
- Child 3-12
- Adolescent 13-17
- Young Adult 18-25
- Adult 26-64
- Older Adult 65+
Languages
- English
In-Network Plans
View All Accepted Plans (12)Gender
MaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Michael J. Polydefkis
Professional Titles
- Director, Cutaneous Nerve Lab
Primary Academic Title
Professor of Neurology
Johns Hopkins Physician
Background
Dr. Michael Polydefkis focuses on neuromuscular diseases, particularly peripheral nerve diseases. He has a special interest in diabetic and HIV-associated peripheral neuropathy. His expertise includes nerve conduction studies, electromyography and nerve, skin and muscle biopsy reading.
Dr. Michael Polydefkis received his medical degree from The Johns Hopkins University School of Medicine. He then became a Howard Hughes Medical Institute research fellow before returning to Johns Hopkins to complete an internship and residency in internal medicine, residency in neurology and a fellowship in neuromuscular diseases.
Centers and Institutes
Find a Clinical Trial
View all trials by this principal investigator.
Research Interests
Clinical trial design and biomarker development, Clinical trials in peripheral neuropathy, Developing treatments for nerve regeneration and neuroprotection in human subjects, Mechanisms of peripheral neuropathies
PubMed - Publications
http://www.ncbi.nlm.nih.gov/pubmed/?term=polydefkis%2C+michael
Honors
- Junior Investigator Award in Diabetic Neuropathy, Peripheral Nerve Society
- Clinician Scientist Award, Johns Hopkins University, USA
- Resident Teaching Award, Johns Hopkins University, USA
Memberships
- American Academy of Neurology
- American Diabetes Association
- American Neurological Association
- Peripheral Nerve Society
- Society for Neuroscience
Locations
- Johns Hopkins Bayview Medical Center
- 4940 Eastern Avenue, Suite 1201, Baltimore, MD 21224
- Get Directions
- phone: 410-550-5624
- fax: 410-550-7694
Expertise
Education
- Fellowship: Johns Hopkins University School of Medicine, Neurology, 2000
- Residency: Johns Hopkins University School of Medicine, Neurology, 1998
- Medical Education: Johns Hopkins University School of Medicine, MD, 1993
Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- Veteran Affairs Community Care Network (Optum-VACCN)
Ratings & Reviews
4.7 out of 5
70 ratings, 27 reviewsThe Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
- 5 out of 5 starsReviewed on 3/4/2026
Dr. Polydefkis was very thorough, remembered every detail during our lengthy appointment, repeated back to me most every concern I had and replied and answered them thoroughly and methodically. I was very impressed and felt he understood my complex case.
- 5 out of 5 starsReviewed on 2/24/2026
Very good experience
- 5 out of 5 starsReviewed on 2/24/2026
Outstanding Doctor
- 5 out of 5 starsReviewed on 2/18/2026
Very thorough education given about my condition
- 5 out of 5 starsReviewed on 2/16/2026
Great!
- 5 out of 5 starsReviewed on 2/10/2026
Dr Polydefkis is a wonderful asset to Hopkins
- 5 out of 5 starsReviewed on 1/12/2026
Great!
- 5 out of 5 starsReviewed on 1/7/2026
Dr. Polydefkis is the best doctor with whom I have ever received care, and he one of best human beings:
- 5 out of 5 starsReviewed on 12/9/2025
He was genuinely pleasant, clearly excellent in his field and answered my questions clearly and succinctly. We discussed my diagnosis and expectations completely.
- 5 out of 5 starsReviewed on 12/9/2025
Excellent
- 5 out of 5 starsReviewed on 11/11/2025
Love Dr Polydefkis and [staff]
- 5 out of 5 starsReviewed on 11/11/2025
Michael Polydefkis always addresses all my questions. He's very professional and patient listening to me. I know I'm in good hands for my treatment for HATTR Amyloidosis.
- 5 out of 5 starsReviewed on 11/5/2025
Good doctor
- 5 out of 5 starsReviewed on 10/28/2025
Outstanding
- 5 out of 5 starsReviewed on 10/15/2025
THIS WAS MY INITIAL VISIT WITH DR. POLYDEFKIS AND HE WAS EXTREMELY THOROUGH. I HAVE BEEN TO MANY DOCTORS AND IT WAS IMPRESSIVE THAT HE WOULD SPEND SO MUCH TIME WITH ME TRYING TO GET ALL OF THE INFORMATION HE NEEDED IN ORDER TO DETERMINE THE DIAGNOSIS. I HAVE FULL CONFIDENCE THAT DR. POLYDEFKIS WILL FIGURE OUT WHAT IS CAUSING MY CHRONIC PAIN/PROBLEMS THAT HAVE BEEN LINGERING FOR MANY YEARS.
- 5 out of 5 starsReviewed on 9/2/2025
Very thorough knowledgeable and exceedingly thoughtful.
- 5 out of 5 starsReviewed on 7/2/2025
Empathetic, state of the art, Great listener
- 5 out of 5 starsReviewed on 7/1/2025
Outstanding, as usual
- 5 out of 5 starsReviewed on 6/18/2025
I have a great deal of respect and confidence in Dr polydefkis
- 5 out of 5 starsReviewed on 6/18/2025
It took 8 months to see this doctor.
- 5 out of 5 starsReviewed on 6/18/2025
Dr Polydefkis was absolutely phenomenal. At the end of the day Dr Polydefkis came in to see us before we left. My wife started tearing up as the doctor was talking to us. On the way home I asked Hera out her tearing up. She said she has never been around a doctor who was so kind and compassionate. I totally agree.
- 5 out of 5 starsReviewed on 5/21/2025
Dr. Polydefkis is the best!! I come from York, PA. I have been seeing this doctor for over 10 years.
- 5 out of 5 starsReviewed on 5/21/2025
Excellent!
- 5 out of 5 starsReviewed on 5/21/2025
Dr. Polydefkis is great!!!
- 4 out of 5 starsReviewed on 5/13/2025
Personable, thoughtful
- 5 out of 5 starsReviewed on 5/7/2025
The best care I've ever had.