Matthew Poy, PhD

• Peavy Endowed Chair in Diabetes

Associate Professor of Medicine

Associate Professor of Physiology, Pharmacology and Therapeutics, Joint Appointment in Pediatrics

600 Sixth Avenue South
Johns Hopkins University School of Medicine
St. Petersburg, FL 33701

Phone: (727) 767-4915
Fax: (727) 767-2821
mpoy1@jhmi.edu

Diabetes and obesity, Mechanisms of metabolic disease, MicroRNA-mediated Gene Regulation, Pancreatic Beta-Cell Biology, Regulatory role of microRNAs and RNA-binding proteins in energy metabolism

https://www.ncbi.nlm.nih.gov/pubmed/?term=poy+mn

https://pure.johnshopkins.edu/en/persons/matthew-poy

• Rathjen T, Yan X, Kononenko NL, Ku MC, Song K, Ferrarese L, Tarallo V, Puchkov D, Kochlamazashvili G, Brachs S, Varela L, Szigeti-Buck K, Yi CX, Schriever SC, Tattikota SG, Carlo AS, Moroni M, Siemens J, Heuser A, van der Weyden L, Birkenfeld AL, Niendorf T, Poulet JFA, Horvath TL, Tschop MH, Heinig M, Trajkovski M, Haucke V, Poy MN. Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1. Nat Neurosci. 2017 Aug;20(8):1096-1103. doi: 10.1038/nn.4590. Epub 2017 Jun 19. PMID: 28628102

• Tattikota SG, Rathjen T, McAnulty SJ, Wessels HH, Akerman I, van de Bunt M, Hausser J, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL, Johnson PR, O'Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom-Feuerstein R, Aberdam D, Poy MN. Argonaute2 mediates compensatory expansion of the pancreatic β cell. Cell Metab. 2014 Jan 7;19(1):122-34. doi: 10.1016/j.cmet.2013.11.015. Epub 2013 Dec 19. PMID: 24361012

• Yan X, Wang Z, Bishop CA, Weitkunat K, Feng X, Tarbier M, Luo J, Friedlander MR, Burkhardt R, Klaus S, Willnow TE, Poy MN. Control of hepatic gluconeogenesis by Argonaute2. Mol Metab. 2018 Oct 9. pii: S2212-8778(18)30794-4. doi: 10.1016/j.molmet.2018.10.003.

• Yan X, Wang Z, Schmidt V, Gauert A, Willnow TE, Heinig M, Poy MN. Cadm2 regulates body weight and energy homeostasis in mice. Mol Metab. 2018 Feb;8:180-188. doi: 10.1016/j.molmet.2017.11.010. Epub 2017 Nov 22. PMID: 29217450

• Yan X, Wang Z, Westberg-Rasmussen S, Tarbier M, Rathjen T, Tattikota SG, Peck BCE, Kanke M, Oxvig C, Frystyk J, Starup-Linde J, Sethupathy P, Friedlander MR, Gregersen S, Poy MN.Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects. J Clin Endocrinol Metab. 2017 Oct 1;102(10):3749-3755. doi: 10.1210/jc.2017-01365. PMID: 28973164

European Research Council Starting Grant, European Research Council, 10/1/10