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Mark Paul David Dow

Mark Paul David Dow, PhD

Highlights

Languages

  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Mark Paul David Dow

Professional Titles

  • REI Laboratory Director: Johns Hopkins Fertility Center
  • Laboratory Director, Division of Reproductive Endocrinology and Infertility

Primary Academic Title

Assistant Professor of Gynecology and Obstetrics

Background

Mark Dow is the laboratory director of the Division of Reproductive Endocrinology and Infertility and Assistant Professor of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine. His areas of expertise include clinical andrology and in vitro fertilization.

Dr. Dow received his Bachelor of Science degree in biochemistry from the University of Wisconsin-Madison and his Doctor or Philosophy degree from Michigan State University in Reproductive Physiology.

Dr. Dow has been serving infertility patients for over 30 years and plays an active role in the American Society of Reproductive Medicine, College of Reproductive Biology, and the Society of Assisted Reproductive Technology.

Research Summary

Dr. Dow’s current interest including streamlining and improving laboratory methods resulting in improved pregnancy outcomes and the patient experience of infertility patients.

PubMed - Publications

Selected Publications

  • Dow MP, Bakke LJ, Cassar CA, Peters MW, Pursley JR, Smith GW. Gonadotropin surge-induced up-regulation of the plasminogen activators (tissue plasminogen activator and urokinase plasminogen activator) and the urokinase plasminogen activator receptor within bovine periovulatory follicular and luteal tissue. Biol Reprod. 2002 May;66(5):1413-21. doi: 10.1095/biolreprod66.5.1413. PMID: 11967205

  • Dow MP, Jones JM, Dumesic DA, Lu Y, Shapiro SS. The successful use of hyperstimulated washed therapeutic donor insemination after standard therapeutic donor insemination has failed. Int J Fertil Menopausal Stud. 1996 Nov-Dec;41(6):516-21. PMID: 9010745

  • Bakke LJ, Dow MP, Cassar CA, Peters MW, Pursley JR, Smith GW. Effect of the preovulatory gonadotropin surge on matrix metalloproteinase (MMP)-14, MMP-2, and tissue inhibitor of metalloproteinases-2 expression within bovine periovulatory follicular and luteal tissue. Biol Reprod. 2002 Jun;66(6):1627-34. doi: 10.1095/biolreprod66.6.1627. PMID: 12021040

  • Bakke LJ, Li Q, Cassar CA, Dow MP, Pursley JR, Smith GW. Gonadotropin surge-induced differential upregulation of collagenase-1 (MMP-1) and collagenase-3 (MMP-13) mRNA and protein in bovine preovulatory follicles. Biol Reprod. 2004 Aug;71(2):605-12. doi: 10.1095/biolreprod.104.027185. Epub 2004 Apr 28. PMID: 15115716

  • Smith MF, Ricke WA, Bakke LJ, Dow MP, Smith GW. Ovarian tissue remodeling: role of matrix metalloproteinases and their inhibitors. Mol Cell Endocrinol. 2002 May 31;191(1):45-56. doi: 10.1016/s0303-7207(02)00054-0. PMID: 12044918.

Honors

  • Journal of Assisted Reproduction & Genetics 1982, 1/1/82
  • Reviewer, Fertility and Sterility, 1/1/81

Memberships

  • American Society of Reproductive Medicine
  • Society for Assisted Reproduction Technology
  • College of Reproductive Biology

Professional Activities

  • American Board of Bioanalysts for the College of Reproductive Biology, Executive Board Member, 4/1/12 - 4/1/14
  • American Society for Reproductive Medicine, Membership Committee, 1/1/16 - 1/1/21
  • Reproductive Laboratory Technology Professional Group, Executive Board Member, 1/1/06 - 1/1/11
  • Society for Assisted Reproductive Technology (SART), Lab Director, 1/1/10 - 1/1/12
  • Society of Reproductive Biologists and Technologist Society, Membership Committee10/2016-10/2021, 1/1/16 - 1/1/21

Expertise

Education

  • Michigan State University, Ph.D., 2002
  • University of Wisconsin (Madison), B.S., 1989