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Mark Gregory Luciano

Mark Gregory Luciano, MD, PhD

Neurosurgery

Accepting New Patients

Highlights

Age Groups Seen

  • Infant 0-2
  • Child 3-12
  • Adolescent 13-17
  • Young Adult 18-25
  • Adult 26-64
  • Older Adult 65+

Languages

  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Mark Gregory Luciano

Professional Titles

  • Director of the Hydrocephalus and Cerebral Fluid Center
  • The Berry-Brem Professor in Neurosurgery

Primary Academic Title

Professor of Neurological Surgery

Johns Hopkins Physician

Logo for Johns Hopkins Physician

Background

Dr. Mark Luciano is the director of the Johns Hopkins Hydrocephalus and Cerebral Fluid Center. A renowned leader in treating hydrocephalus, Dr. Luciano is distinguished both nationally and internationally for his research and educational and clinical work in neuroendoscopy.

Dr. Luciano treats adults with hydrocephalus, pseudotumor cerebri, intracranial hypotension, Chiari malformations, and cerebral and spinal cysts. He has significant expertise treating children and adults with cerebrospinal fluid leaks and congenital disorders.
Among his accomplishments in neuroscience research and biomedical engineering are his investigation of the cerebrovascular response to hydrocephalus and the invention of a unique device for control of intracranial pressure (ICP) pulsatility to increase blood flow. His National Institutes of Health-funded studies have explored prolonged compression and hypoxia in the brain as a result of hydrocephalus, as well as the interaction between cerebrospinal fluid and vascular systems.

Find a Clinical Trial

View all trials by this principal investigator.

Recent News Articles and Media Coverage

  • Billy Joel cancels all concerts after brain disorder diagnosis, CBC (May 23, 2025)

  • Holistic Treatment for CSF Disorders, NeuroLogic (Fall 2015)

Additional Academic Titles

Professor of Biomedical Engineering, Professor of Pediatrics

Research Interests

  • Cerebral blood flow
  • Cerebrovascular function
  • Chiari malformation
  • Hydrocephalus

Patents

  • Device for increasing CBF through cardiac-gaited cranial volume alteration, US12/770,276, 1/1/15
  • Continuation Device for increasing CBF through cardiac-gaited cranial volume alteration, US12/090,640, 1/1/15

Memberships

  • World Neurosurgery,

    Section Editor, Hydrocephalus and CSF Disorders

  • Chiari and Syringomyelia Foundation,

    Medical Advisory Board, Vice Chair

  • Adult Hydrocephalus Clinical Research Network
  • International Hydrocephalus Research Society
  • Hydrocephalus Association,

    Medical Advisory Board

Locations

  1. Levi Watkins, Jr., M.D., Outpatient Center
  2. Johns Hopkins Bayview Medical Center

Expertise

Education

  • Fellowship: Boston Children's Hospital, Pediatric Neurosurgery, 1993
  • Residency: Hospital of the University of Pennsylvania , Neurosurgery, 1992
  • Graduate School: Tulane University School of Medicine, PhD, 1985
  • Medical Education: University of Chicago School of Medicine, MD, 1985

Board Certifications

  • Neurological Surgery: American Board of Neurological Surgery, 1998

Insurance

Please contact the location directly to confirm your health plan is accepted.
Search plans
  • Aetna
  • CareFirst
  • Cigna
  • First Health
  • Geisinger Health Plan
  • HealthSmart/Accel
  • Johns Hopkins Health Plans
  • MultiPlan
  • Pennsylvania's Preferred Health Networks (PPHN)
  • Point Comfort Underwriters
  • Private Healthcare Systems (PHCS)
  • Veteran Affairs Community Care Network (Optum-VACCN)

Ratings & Reviews

4.7 out of 5

178 ratings, 67 reviews

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Overall Rating by Patient
Provider Listened Carefully
Provider Explained Things Clearly
Provider Knew Medical History
Provider Showed Respect
Provider Spent Enough Time
Search reviews
    5 out of 5 stars
    Reviewed on 3/12/2026

    Surgeon outstanding

    5 out of 5 stars
    Reviewed on 3/10/2026

    Dr. Luciano is the most wonderful, caring and best doctor/surgeon in the entire world. He is personable, kind and humble. Attributes that are unbelievable for this prestigious doctor/surgeon.

    5 out of 5 stars
    Reviewed on 3/10/2026

    He was very professional explained exactly the surgery that was going to be performed on me and asked me a few times any questions or any concerns he was very good

    5 out of 5 stars
    Reviewed on 3/5/2026

    I love Dr. Luciano. I have had neurosurgeons my whole life and he is the best one I have had since I was a child.

    5 out of 5 stars
    Reviewed on 2/26/2026

    Very knowledgeable and competent. Great listener you and communicator

    5 out of 5 stars
    Reviewed on 2/26/2026

    Dr Luciano, the nurse practitioner and the medical assistant were all awesome, helpful, caring

    5 out of 5 stars
    Reviewed on 2/26/2026

    Excellent in every way.

    5 out of 5 stars
    Reviewed on 2/24/2026

    Dr. Luciano is very knowledgeable, personable, and easy to talk to. It is always a pleasure to converse with him about my hydrocephalus. He is very reassuring and positive.

    5 out of 5 stars
    Reviewed on 2/24/2026

    Dr Luciano is the expert in treating my condition NPH. His advice & treatment have been accurate and successful

    5 out of 5 stars
    Reviewed on 2/17/2026

    He took the time to read my health history.

    5 out of 5 stars
    Reviewed on 2/17/2026

    Very good to speak directly to Dr. Luciano again and appreciated his advice.

    5 out of 5 stars
    Reviewed on 2/10/2026

    All good

    5 out of 5 stars
    Reviewed on 2/10/2026

    Love Dr. Luciano! Very caring and attentive.

    5 out of 5 stars
    Reviewed on 2/5/2026

    Very satisfied with my visit.Waited quite long to see doctor, but when he arrived we had an informative visit. Very pleased

    5 out of 5 stars
    Reviewed on 2/2/2026

    Excellent service

    5 out of 5 stars
    Reviewed on 1/29/2026

    Dr. Luciano was very good answering questions my daughter and I had about next steps

    5 out of 5 stars
    Reviewed on 1/29/2026

    Over 1 hour delay with no explanation

    5 out of 5 stars
    Reviewed on 1/22/2026

    [staff] and Dr Luciano

    5 out of 5 stars
    Reviewed on 1/22/2026

    Nurse practitioner was excellent

    5 out of 5 stars
    Reviewed on 1/22/2026

    Expert in shunt cases.

    5 out of 5 stars
    Reviewed on 1/20/2026

    Very Effective and Efficient in all aspects

    5 out of 5 stars
    Reviewed on 1/20/2026

    Very good at what he does

    5 out of 5 stars
    Reviewed on 1/20/2026

    Dr Luciano is the best Explained everything in a way I could understand what was going on and how to help me with my treatment

    5 out of 5 stars
    Reviewed on 1/16/2026

    Happy that Dr. Luciano is my doctor

    5 out of 5 stars
    Reviewed on 1/16/2026

    He was very knowledgeable and professional. I would highly recommend him

    5 out of 5 stars
    Reviewed on 12/4/2025

    Excellent, compassionate, understanding

    5 out of 5 stars
    Reviewed on 11/25/2025

    I have the utmost confidence in Dr Luciano

    5 out of 5 stars
    Reviewed on 11/20/2025

    Great doctors

    5 out of 5 stars
    Reviewed on 11/20/2025

    I love Dr. Luciano. I've haven't had a neurosurgeon who cares so much about his patients. He's always friendly, smiles, explains things if I have questions and never treats me like I'm not important.

    5 out of 5 stars
    Reviewed on 11/20/2025

    Dr Luciano is a wonderful doctor. I'm very lucky to have found him.

    5 out of 5 stars
    Reviewed on 11/18/2025

    Famous and. Highly regarded

    5 out of 5 stars
    Reviewed on 11/13/2025

    It was a good visit. He adjusted my shunt. I'm feeling much better.

    5 out of 5 stars
    Reviewed on 11/6/2025

    Dr. Luciano is wonderful!!!!

    5 out of 5 stars
    Reviewed on 11/4/2025

    [staff] is amazing. She takes the time to explain things to me, and she worked with Dr. Luciano to make sure that we were doing what made sense based on my symptoms. The physician assistant was also fantastic!

    5 out of 5 stars
    Reviewed on 10/30/2025

    DR Mark Luciano was friendly and knowledgeable

    5 out of 5 stars
    Reviewed on 10/23/2025

    I feel that I finally have a path forward to get better.

    5 out of 5 stars
    Reviewed on 10/7/2025

    Dr. Luciano has been my neurosurgeon for almost 18 years, and thanks to his care, I was able to get my life back, go back to school and get an advanced degree, get off disability, and have an amazing life. I am so thankful I found him! He is someone who truly makes a difference in the lives of his patients.

    5 out of 5 stars
    Reviewed on 10/7/2025

    Dr. Luciano came up to talk to me about how everything happened and what he was going to do to fix it.

    5 out of 5 stars
    Reviewed on 9/30/2025

    Excellent

    5 out of 5 stars
    Reviewed on 9/18/2025

    Very knowledgeable

    5 out of 5 stars
    Reviewed on 9/16/2025

    He was amazing. Knowledgeable, professional, kind, caring.

    5 out of 5 stars
    Reviewed on 8/28/2025

    Dr. Luciano was incredibly kind and understanding as always. We drive from Connecticut for our appointments because of the quality of care he provides for me and my family members with Hydrocephalus.

    5 out of 5 stars
    Reviewed on 8/21/2025

    Good

    3 out of 5 stars
    Reviewed on 8/14/2025

    Would have liked to see Dr in person for yearly visit about shunt

    5 out of 5 stars
    Reviewed on 7/31/2025

    CONCERNED,KIND,COVERED ALL ASPECTS OF CARE WITH GREAT DETAIL LISTEND AND ANSWERD ALL QUESTIONS.

    5 out of 5 stars
    Reviewed on 7/31/2025

    Very efficient. Excellent listener

    5 out of 5 stars
    Reviewed on 7/24/2025

    Visit was excellent once we saw Dr. Luciano. However, we waited more than 2 hours past our appointment time before he came in. We were on the verge of leaving without seeing him because we had another time commitment.

    5 out of 5 stars
    Reviewed on 7/24/2025

    Dr Luciano gave me valuable info, advice and thoughts. Thkful I found him.

    5 out of 5 stars
    Reviewed on 7/17/2025

    Very good

    5 out of 5 stars
    Reviewed on 7/15/2025

    Great visit and taken on time

    5 out of 5 stars
    Reviewed on 7/10/2025

    Excellent / outstanding

    5 out of 5 stars
    Reviewed on 7/10/2025

    Dr. Luciano and [staff] are both awesome. I am so glad I have them to come to when I have issues with my shunt.

    5 out of 5 stars
    Reviewed on 7/8/2025

    Nice guy

    5 out of 5 stars
    Reviewed on 7/3/2025

    I've never had a better doctor than Dr. Luciano. He truly cares for his patients and he listens.

    5 out of 5 stars
    Reviewed on 7/3/2025

    Dr Luciano is amazing! Thats why I live in another state and still see him. He's veey knowledgeable and genuinely wants to help.

    5 out of 5 stars
    Reviewed on 7/3/2025

    Dr Luciano was available prior to surgery and later at post op checkup. He took the time to explain my condition and his team was very helpful.

    5 out of 5 stars
    Reviewed on 7/1/2025

    Very good visit.

    5 out of 5 stars
    Reviewed on 7/1/2025

    Dr. Luciano and his team care so much about their patients. All members, including med students, know about the patient they are assigned to and explain very well about what they are doing and how (eg. MRI).

    5 out of 5 stars
    Reviewed on 6/26/2025

    Genuine compassionate professional kind expressive knowledgeable even a soft sense of humor

    5 out of 5 stars
    Reviewed on 6/12/2025

    My doctor has always treated me with respect. He has makes me feel like he has all the time in the world to listen to me. Never feel rushed out. Dr. Luciano is a wonderful doctor. I trust him with my life. Literally as many times he operated on my brain.

    5 out of 5 stars
    Reviewed on 5/13/2025

    Easy to talk to. Asked good questions. Nice patient manner.

    5 out of 5 stars
    Reviewed on 5/8/2025

    He was very friendly and helpful in giving me suggestions on what to do about my condition.

    5 out of 5 stars
    Reviewed on 5/8/2025

    Dr. Luciano knew my complicated stroke history before saw me. His enthusiasm instantly eliminated my fear and nervousness.

    5 out of 5 stars
    Reviewed on 5/6/2025

    Dr. Luciano and [staff] make the best team. [staff] is unbelievably knowledgeable and always asks great questions. Dr. Luciano always gives me great energy to carry on.

    2 out of 5 stars
    Reviewed on 4/24/2025

    The Dr. Seems to do whatever his assistant says. Doesn't take time. Feel like no time for me . Doesn't really listen to my concerns and symptoms.

    5 out of 5 stars
    Reviewed on 4/24/2025

    Simply world class.

    5 out of 5 stars
    Reviewed on 4/24/2025

    Great provider