Marjan Gharagozloo, PhD

Dr. Marjan Gharagozloo’s research aims to uncover the immunological mechanisms driving chronic neuroinflammation and neurodegeneration in multiple sclerosis (MS). She earned her PhD in immunology from the Université de Sherbrooke (Sherbrooke, QC, Canada) and completed a postdoctoral fellowship in the Division of Neuroimmunology at Johns Hopkins Medicine. Her work is supported by grants from the National MS Society, the Race to Erase MS Foundation, and the Maryland Stem Cell Research Fund. With this support, she investigates how the innate immune regulator NLRX1 influences glia-mediated inflammation and neurodegeneration, and develops therapeutic strategies to slow neurodegeneration in progressive MS. Her approach integrates transgenic mouse models, human induced pluripotent stem cell (iPSC)–derived systems, and postmortem human tissues to identify targets for innovative treatments for MS and related neurodegenerative diseases.