Kristen A. Marrone, MD

Professional Titles

• Program Director, Hematology/Medical Oncology Fellowship Program

Primary Academic Title

Associate Professor of Oncology

Background

Centers and Institutes

Sidney Kimmel Comprehensive Cancer Center

Clinical Trial Keywords

Non-Small Cell Lung Cancer (NSCLC); epidermal derived growth factor receptor (EGFR); KRAS

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Research Interests

Immunotherapy, Non-small Cell Lung Cancer (NSCLC), Oncogene Mutated NSCLC, Tumor Metabolism

Research Summary

Non-small cell lung cancer (NSCLC); oncogene mutated NSCLC; immunotherapy; tumor metabolism

Selected Publications

• Balaji A, Zhang J, Wills B, Marrone KA, Elmariah H, Yarchoan M, Zimmerman JW, Hajjir K, Venkatraman D, Armstrong DK, Laheru DA, Mehra R, Ho WJ, Reuss JE, Heng J, Vellanki P, Donehower RC, Holdhoff M, Naidoo J. “Immune-Related Adverse Events Requiring Hospitalization: Spectrum of Toxicity, Treatment, and Outcomes.” J Oncol Pract. 2019 Sep;15(9):e825-e834

• Cortazar FB, Kibbelaar ZA, Glezerman IG, Abudayyeh A, Mamlouk O, Motwani SS, Murakami N, Herrmann SM, Manohar S, Shirali AC, Kitchlu A, Shirazian S, Assal A, Vijayan A, Renaghan AD, Ortiz-Melo DI, Rangarajan S, Malik AB, Hogan JJ, Dinh AR, Shin DS, Marrone KA, Mithani Z, Johnson DB, Hosseini A, Uprety D, Sharma S, Gupta S, Reynolds KL, Sise ME, Leaf DE. “Clinical Features and Outcomes of Immune Checkpoint Inhibitor-Associated AKI: A Multicenter Study.” J Am Soc Nephrol. 2020 Feb;31(2):435-446

• Suresh K, Naidoo J, Zhong Q, Xiong Y, Mammen J, de Flores MV, Cappelli L, Balaji A, Palmer T, Forde PM, Anagnostou V, Ettinger DS, Marrone KA, Kelly RJ, Hann CL, Levy B, Feliciano JL, Lin CT, Feller-Kopman D, Lerner AD, Lee H, Shafiq M, Yarmus L, Lipson EJ, Soloski M, Brahmer JR, Danoff SK, D'Alessio F. “The alveolar immune cell landscape is dysregulated in checkpoint inhibitor pneumonitis.” J Clin Invest. 2019 Jul 16;130:4305-4315. Parikh AB, Marrone KA, Becker DJ, Brahmer JR, Ettinger DS, Levy BP. “A pooled analysis of two phase II trials evaluating metformin plus platinum-based chemotherapy in advanced non-small cell lung cancer.” Cancer Treat Res Commun. 2019 May 10;20: 100150

• Topper MJ, Vaz M, Marrone KA, Brahmer JR, Baylin SB. “The emerging role of epigenetic therapeutics in immuno-oncology.” Nat Rev Clin Oncol. 2020 Feb;17(2):75-90

• Zhang J, Ji Z, Caushi JX, El Asmar M, Anagnostou V, Cottrell TR, Chan HY, Suri P, Guo H, Merghoub T, Chaft JE, Reuss JE, Tam AJ, Blosser RL, Abu-Akeel M, Sidhom JW, Zhao N, Ha JS, Jones DR, Marrone KA, Naidoo J, Gabrielson E, Taube JM, Velculescu VE, Brahmer JR, Housseau F, Hellmann MD, Forde PM, Pardoll DM, Ji H, Smith KN. “Compartmental Analysis of T-cell Clonal Dynamics as a Function of Pathologic Response to Neoadjuvant PD-1 Blockade in Resectable Non-Small Cell Lung Cancer.” Clin Cancer Res. 2019 Nov 21

Courses & Syllabi

• Mock Tumor Board, 1/1/18
• Epidemiology, Staging and Molecular Diagnosis in Cancer, 1/1/18
• Genes to Society Pulmonary Course, Student Presentations, 1/1/17
• Summer Lecture Series-Lung Cancer Case Review, 1/1/17
• Oncologic Emergencies, 1/1/16
• Genes to Society Oncology Course, 1/1/16

Honors

• Gold Humanism Honor Society, 1/1/13
• Alpha Omega Alpha, Member, 1/1/11

Graduate Program Affiliations

• Oncology - Upper Aerodigestive Disease

Memberships

• American Association of Cancer Research
• American Society of Clinical Oncology (ASCO)
• International Association for the Study of Lung Cancer (IASLC)
• Society for Immunotherapy in Cancer