Konstantinos Aronis, MD, PhD

• Director, Adult Congenital Heart Disease Complex Ablation Program
• Associate Director, Ventricular Tachycardia Ablation Program

Assistant Professor of Medicine

https://www.linkedin.com/in/aronismd/

Ventricular tachycardia, VT ablation, catheter ablation, ventricular fibrillation, adult congenital heart disease, ACHD, congenital arrhythmia, atrial arrhythmia, atrial fibrillation, supraventricular tachycardia, epicardial ablation, LVAD, hybrid surgical ablation, VATS ablation, conduction system pacing, leadless pacemaker, cardiac implantable electronic device, ICD, sudden cardiac death, tetralogy of Fallot, Fontan, digital twin, computational electrophysiology, cardiac imaging, electroanatomic mapping, arrhythmia mapping, biological pacemaker, premature ventricular complexes, electrophysiology study.

• Site Principal Investigator, NIH-funded EARLY-VT multicenter trial (University of Rochester network).
• Co-Investigator (pending), DARPA VITAL Program "ELECTRA" project on advanced arrhythmia technologies.
• Participating investigator within the Rochester multicenter EP trial network (e.g., PIVATAL, CONTEMPT-ICD).

https://www.hopkinsmedicine.org/news/articles/2024/02/creative-approaches-for-patients-with-congenital-heart-disease-and-electrical-heart-complications

1800 Orleans Street
Zyed Tower Suite 7120
Baltimore, MD 21287

karonis1@jh.edu

• Catheter ablation and longitudinal management of arrhythmias in complex adult congenital heart disease (ACHD).
• Complex ventricular tachycardia ablation — epicardial, intraoperative/LVAD-concurrent, and ventricular fibrillation ablation.
• Hybrid surgical, VATS, and mini-thoracotomy approaches to VT ablation.
• Integration of advanced cardiac imaging into electrophysiology procedures.
• Computational electrophysiology and patient-specific digital-twin modeling (Trayanova lab collaboration).

• Author of 80+ peer-reviewed publications (60 original research articles, 11 reviews, multiple case reports, editorials, and a scientific statement); h-index 31 with ~3,300 citations.
• Co-author on the landmark NEJM digital-twin–guided VT ablation trial.
• Lead inventor on U.S. Patent No. 12,531,145 for real-time image-guided arrhythmia localization.
• Director/PI of the IRB-approved JHH ACHD Electrophysiology Registry (~40 patients enrolled).
• Clinical collaborator on a pre-clinical biological pacemaker program (large-animal, catheter-based delivery).

https://scholar.google.com/citations?hl=en&user=jUCdrAcAAAAJ&view_op=list_works&gmla=AOV7GLMz3PqsPHrCKq1ome4iTDkHRoc10fudEBvYh6w15Klj-Hr1vaV9ormfRRMxmoAQdFIWJjbdXy-XEZa-s2bq

https://www.ncbi.nlm.nih.gov/myncbi/kostantinos.aronis.1/bibliography/public/

https://pure.johnshopkins.edu/en/persons/konstantinos-aronis/

https://www.researchgate.net/profile/Konstantinos-Aronis

• Aronis KN, Ali RL, Prakosa A, Ashikaga H, Berger RD, Hakim JB, Liang J, Tandri H, Teng F, Chrispin J, Trayanova NA. Accurate Conduction Velocity Maps and Their Association With Scar Distribution on Magnetic Resonance Imaging in Patients With Postinfarction Ventricular Tachycardias. Circ Arrhythm Electrophysiol. 2020 Apr;13(4):e007792

• Aronis KN, Berger RD, Calkins H, Chrispin J, Marine JE, Spragg DD, Tao S, Tandri H, Ashikaga H. Is human atrial fibrillation stochastic or deterministic? -Insights from missing ordinal patterns and causal entropy-complexity plane analysis. Chaos. 2018 Jun;28(6):063130

• Aronis KN, Okada DR, Xie E, Daimee UA, Prakosa A, Gilotra NA, Wu KC, Trayanova N, Chrispin J. Spatial Dispersion Analysis of LGE-CMR for Prediction of Ventricular Arrhythmias in Patients with Cardiac Sarcoidosis. Pacing Clin Electrophysiol. 2021 Dec;44(12):2067-2074

• Aronis KN, Prakosa A, Bergamaschi T, Berger RD, Boyle PM, Chrispin J, Ju S, Marine JE, Sinha S, Tandri H, Ashikaga H, Trayanova NA. Characterization of the Electrophysiologic Remodeling of Patients With Ischemic Cardiomyopathy by Clinical Measurements and Computer Simulations Coupled With Machine Learning. Front Physiol. 2021 Jul 14;12:684149

• Aronis KN, Yang E, Barnes BT, Cedars A, De La Uz CM, Barth AS. Left bundle pacing in a patient with atrioventricular canal defect presenting with atrial standstill and junctional bradycardia. Heart Rhythm Case Reports. Volume 9, Issue, P314-318, May 2023

• Director, Electrophysiology Elective Rotation (JHH) — established invasive, device, and consultative EP electives for general cardiology fellows beyond ACGME-required time; 2–3 fellows complete each year.
• Pre-EP Curriculum (JHH) — designed a structured preparatory curriculum for fellows entering EP fellowship, including procedural exposure at Sibley Memorial Hospital and guided didactic resources.
• Core Faculty, ACGME-Accredited ACHD Fellowship (JHH) — sole electrophysiology-expertise core faculty, delivering EP didactics and case-based instruction.

U.S. Patent No. 12,531,145 — "System and Method for Real-Time Guidance of an Electrophysiology Catheter for Targeting a Location of Origin of an Arrhythmia." Lead Inventor (with Berger RD, Trayanova NA, Zhou S, Tandri H). Filed December 2, 2020; issued January 20, 2026. Johns Hopkins University (Ref. P15775-03).

• The W. Leigh Thompson Excellence in Research: Clinical Research Fellow Award Finalist, The Johns Hopkins Department of Medicine/ Whiting School of Engineering, 1/1/19
• Travel Scholarship; Heart Rhythm Society 40th Annual Meeting, Heart Rhythm Society, 1/1/19
• 1st Prize; BIDMC - Harvard Medical School Residents/Fellows Clinical Research Day, BIDMC - Harvard Medical School, 1/1/11

• Invited regional, national, and international lectures on complex ventricular tachycardia ablation, adult congenital heart disease electrophysiology, and computational/digital-twin approaches to arrhythmia management.
• Conference presentations at Heart Rhythm Society (HRS) and related scientific sessions, including travel-award–recognized work.
• Fellowship and divisional teaching conferences; named 2025 Teacher of the Year by the JHH Cardiology Fellowship.

• Fellowships

• Fellow, American College of Cardiology (FACC)
• Fellow, Heart Rhythm Society (FHRS)
• Fellow, European Society of Cardiology (FESC)
• Fellow, European Heart Rhythm Association (FEHRA)

• Society Memberships

• American College of Cardiology (ACC)
• Heart Rhythm Society (HRS)
• Pediatric and Congenital Electrophysiology Society (PACES)
• International Society for Adult Congenital Heart Disease (ISACHD)
• European Society of Cardiology (ESC)
• European Heart Rhythm Association (EHRA)

Media and Professional Association Recognitions

Dr. Aronis's work has been featured by Johns Hopkins Medicine, including a 2024 profile of his innovative approaches to electrical heart complications in congenital heart disease—highlighting 3D-printed cardiac modeling for conduction system pacing and the first intraoperative atrial tachycardia ablation in an adult congenital patient. His role as co-author on the landmark NEJM digital-twin ventricular tachycardia ablation trial was covered by Johns Hopkins University News. He was named 2025 Teacher of the Year by the Johns Hopkins Cardiology Fellowship, and is a Fellow of the American College of Cardiology, Heart Rhythm Society, European Society of Cardiology, and EHRA.

Editorships of Academic Journals

Dr. Aronis serves in editorial leadership across several peer-reviewed cardiovascular journals. He is an Associate Editor for JACC: Case Reports and served as Guest Editor-in-Chief for its ECG Challenge special issue. He has been an Associate Editor for Frontiers in Physiology since 2020 and a Review Editor for Frontiers in Medical Technology. He is a Section Board Member for the Journal of Cardiovascular Development and Disease and an Editorial Board member for Cardiogenetics. He also serves as Guest Editor for the second edition of the Advances in Cardiac Resynchronization Treatment collection in the Journal of Clinical Medicine.

Leadership Positions in Professional Associations

Dr. Aronis holds national leadership roles across major cardiology and electrophysiology societies. He serves on the American College of Cardiology Electrophysiology Section Leadership Council (2026–2029) and the ABIM Cardiac Electrophysiology Board Item-Writing Committee (reappointed 2026–2028). He is a member of the ACC/ABIM EP Collaborative Maintenance Pathway Standard-Setting Committee, the Heart Rhythm Society 2026 Program Committee (Pediatric and Adult Congenital EP Section), and the PACES Communications Committee. He served on the writing committee for the HRS/ISACHD/PACES Scientific Statement on adult congenital EP programs, authoring its Quality of Care section, and is a Department of Defense CDMRP peer reviewer.