Katie Bever, MD

Background

Centers and Institutes

• Precision Medicine Center of Excellence for Pancreatic Cancer
• Sidney Kimmel Comprehensive Cancer Center

Clinical Trials Summary

Paclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma

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Research Summary

Dr. Bever’s research focuses on understanding tumor susceptibility to and mechanisms of resistance to immunotherapy through clinical and translational investigations in gastrointestinal cancers. She is also interested in developing strategies to overcome immunotherapy resistance through rationally selected combinations.

Selected Publications

• Bever KM, Masha LI, Sun F, Stern L, Havasi A, Berk JL, Sanchorawala V, Seldin DC, Sloan JM. “Risk factors for venous thromboembolism in immunoglobulin light chain amyloidosis.” Haematologica. 2016;101(1):86-90

• Bever KM, Sugar EA, Bigelow E, Sharma R, Laheru D, Wolfgang CL, Jaffee EM, Anders RA, De Jesus-Acosta A, Zheng L. “The prognostic value of stroma in pancreatic cancer for patients receiving adjuvant therapy.” HPB (Oxford). 2015;17(4):292-8

• Cosgrove MS, Bever K, Avalos JL, Muhammad S, Zhang X, Wolberger C. “The structural basis of sirtuin substrate affinity.” Biochemistry. 2006;45(24):7511-21

• Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, Zaheer A, Fisher GA, Crocenzi TS, Lee JJ, Greten TF, Duffy AG, Ciombor KK, Eyring AD, Lam BH, Joe A, Kang SP, Holdhoff M, Danilova L, Cope L, Meyer C, Zhou S, Goldberg RM, Armstrong DK, Bever KM, Fader AN, Taube J, Housseau F, Spetzler D, Xiao N, Pardoll DM, Papadopoulos N, Kinzler KW, Eshleman JR, Vogelstein B, Anders RA, Diaz LA Jr. “Mismatch-repair deficiency predicts response of solid tumors to PD-1 blockade.” Science. 2017;357(6349):409?413

• Pudusseri A, Sanchorawala V, Sloan JM, Bever KM, Doros G, Kataria S, Sarosiek S. “Prevalence and prognostic value of D-dimer elevation in patients with AL amyloidosis.” Am J Hematol. 2019 Oct;94(10):1098-1103

Honors

• Pearl M. Stetler Fellowship Award, Johns Hopkins, 1/1/18
• Translational Cancer Research Award, Swim Across America, 1/1/17
• First Place, Senior Resident Academic Day Poster Session, Boston University School of Medicine, 1/1/14
• Selected as "Mini-Chief," Internal Medicine Residency Program, Boston University School of Medicine, 1/1/13
• Resident Teaching Award, Boston University School of Medicine, 1/1/13
• Medical Student Abstract Competition Winner, American College of Physicians Annual Meeting, 1/1/10
• First Place, Graduate Student Category, Department of Surgery Poster Session, Johns Hopkins University, 1/1/10

Lectures & Presentations

Morbidity and Mortality Oncology Grand Rounds, Lecture, Johns Hopkins Hospital, 10/1/17

Memberships

• Society for Immunotherapy of Cancer
• American Association of Clinical Research
• American Society of Clinical Oncology
• American Society of Hematology