James Joseph Thompson, DO

James J. Thompson, D.O., is a diagnostic radiologist and physicist specializing in advanced cardiovascular imaging, including cardiac CT and cardiovascular MRI. With more than 20 years of experience in cardiovascular imaging, his work combines clinical medicine, imaging physics, and emerging technologies in artificial intelligence. Dr. Thompson has extensive experience developing advanced cardiovascular imaging programs, including launching cardiac CT and cardiovascular MRI services, developing imaging protocols, and educating physicians and clinical teams. His clinical interests include coronary CT angiography, cardiovascular MRI, adult congenital heart disease, preventative cardiovascular imaging and quantitative imaging. His academic and research interests focus on the integration of artificial intelligence and advanced imaging technologies into cardiovascular care, with particular emphasis on earlier disease detection, improved diagnostic capabilities and the development of clinically meaningful imaging technologies. In addition to his clinical work at Johns Hopkins All Children's Hospital, Dr. Thompson hold academic appointments as an Assistant Professor at the University of South Florida and the University of Central Florida. He is also Co-Founder and Course Director of the Southwest Florida Cardiovascular Imaging Symposium, an educational program focused on advances in cardiovascular imaging, artificial intelligence and emerging technologies. 

• Johns Hopkins All Children's Hospital
• Pediatric Radiology

Cardiovascular Business, "FDA Clears New AI-Enabled Coronary Plaque Analysis Software" 

Advanced cardiovascular imaging; coronary CT angiography (CCTA); cardiovascular magnetic resonance (CMR); artificial intelligence and machine learning in cardiovascular imaging; imaging physics; photon-counting CT; radiation dose optimization; quantitative cardiovascular imaging; coronary plaque analysis; preventive cardiovascular imaging; adult congenital heart disease imaging; AI-enabled image acquisition, reconstruction and post-processing; emerging cardiovascular imaging technologies.

Dr. Thompson’s academic and research interests focus on the integration of advanced cardiovascular imaging, imaging physics, and artificial intelligence to improve cardiovascular disease detection and clinical care. His work includes coronary CT angiography, cardiovascular MRI, photon-counting CT, radiation dose optimization, quantitative imaging, coronary plaque assessment, and AI-enabled image acquisition, reconstruction, analysis, and workflow optimization. He has a particular interest in translating emerging imaging technologies into clinically meaningful tools for earlier disease detection, improved diagnostic precision, and more personalized cardiovascular care.

Einstein AJ, Wolff SD, Manheimer ED, Thompson J, Terry S, Uretsky S, Pilip A, Peters MR. “Comparison of Image Quality and Radiation Dose of Coronary Computed Tomographic Angiography Between Conventional Helical Scanning and a Strategy Incorporating Sequential Scanning.” American Journal of Cardiology. 2009;104(10):1343–1350. PMID: 19892048.

Levy EI, Ecker RD, Thompson JJ, Rosella PA, Hanel RA, Guterman LR, Hopkins LN. “Toward Clinical Equipoise: The Current Case for Carotid Angioplasty and Stent Placement.” Neurosurgical Focus. 2005;18(1):E3. PMID: 15669797.

American Osteopathic College of Radiology (AOCR), Recognition for Exceptional Scientific Presentations, 2026 Annual Convention

American Osteopathic College of Radiology (AOCR), Recognition for Exceptional Scientific Presentations, 2025 Annual Convention, Radiology 911, Amelia Island, Florida

CardioAI SCCT Level I Virtual Course, “CT Physics, Technology & Image Acquisition: Scanner Types, Gating, Spatial/Temporal Resolution,” Speaker and Session Chair, June 28, 2026.

Southwest Florida Cardiovascular Imaging Symposium, Knoxville, “FAI: The Inflammation Story,” Speaker, 2026. 

American Osteopathic College of Radiology (AOCR), “Multimodality Imaging of Cardiac Amyloidosis (SAM Lecture),” Presenter with Firas Al Badarin, MD, 2026

North American Society for Cardiovascular Imaging (NASCI), “Incorporating AI into Congenital Heart Imaging,” Speaker, September 29, 2025. The official program specifically names James Thompson, DO.

Hosted Dinner Symposium, Dubai, UAE,“Artificial Intelligence in Cardiovascular Imaging: Transforming Practice and Shaping the Future, From Pixels to Precision,” Speaker, October 4, 2025.

Circle Cardiovascular Imaging / Society of Cardiovascular Computed Tomography (SCCT), “Optimizing Time and Resources Through Advanced Cardiac Imaging Post-Processing,” Speaker, August 20, 2025. 

American Osteopathic College of Radiology (AOCR), “Cardiac CCTA in the ER: Incorporating AI/Machine Learning,” Speaker, April 29, 2025. 

American Osteopathic College of Radiology (AOCR), “Traumatic and Non-Traumatic Thoracic Emergencies,” Speaker, April 29, 2025.

Southwest Florida Cardiovascular Imaging Symposium / SCCT, “The Future of Heart Care: Cardiac CT and AI Technologies,” Program Chair, February 22, 2025, Scottsdale, Arizona. ⁠

HeartFlow / ISCVDP 2025, “Elevating Preventive Care with Coronary CTA & AI-Driven Insights,” Presenter, February 8, 2025, Sarasota, Florida.

Society for Cardiovascular Magnetic Resonance (SCMR) 2025, “Rapid Fire 02: Tissue Characterization I,” Moderator, January 30, 2025. 

Southwest Florida Cardiovascular Imaging Symposium / SCCT, “Advancements in Cardiac CT & Emerging Technologies in Artificial Intelligence,” Program Chair, November 9, 2024.

North American Society for Cardiovascular Imaging (NASCI), “Cardiac CTA Multiplanar Technique,” Cardiac CT Bootcamp, Speaker, September 21, 2024, Boston, Massachusetts.

Florida Chapter of the American College of Cardiology Annual Meeting, Moderator, 2024.

Society for Cardiovascular Magnetic Resonance (SCMR) Global Conference, “Cost Effectiveness,” Moderator, January 25, 2024, London, United Kingdom.

Southwest Florida Cardiovascular Imaging Symposium (SWFLCIS), Co-Founder and Course Director

Society of Cardiovascular Computed Tomography (SCCT), Corporate Relations Committee Member, 2024–2027