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Isam Nasr

Isam Nasr, MD

Pediatric General Surgery

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Highlights

Age Groups Seen

  • Infant 0-2
  • Child 3-12
  • Adolescent 13-17

Languages

  • French
  • Arabic
  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Isam Nasr

Professional Titles

  • Director of Pediatric Trauma Program, Division of Pediatric Surgery
  • Co-Director of the Pediatric Surgical Colorectal Program

Primary Academic Title

Associate Professor of Clinical Pediatric Surgery

Johns Hopkins Physician

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Background

Isam Waddah Nasr is a pediatric surgeon in the Johns Hopkins Department of Surgery and Johns Hopkins Children’s Center. He joined the Children’s Center in 2015, after completing fellowships in both surgical critical care and pediatric surgery at the Children’s Hospital of Pittsburgh.

Dr. Nasr is director of the Johns Hopkins Children’s Center Pediatric Trauma Program and co-director of the Pediatric Colorectal Program. He has developed significant national recognition in the field of pediatric trauma through both his clinical and basic science research, where he has made substantial scholarly contributions. A nationally recognized expert in the field of pediatric colorectal surgery — an area in which he has a large national and international referral base — Dr. Nasr has a track record for clinical excellence that is well established in and outside of the Johns Hopkins system.

Trained in minimally invasive surgical procedures and skilled in the management of congenital colorectal anomalies, Dr. Nasr focuses on congenital pediatric colorectal conditions such as Hirschsprung disease, anorectal malformations, cloacal exstrophy and idiopathic chronic constipation — one of the most clinically challenging pediatric patient populations to treat. He performs a thorough review and workup of all patients who are referred to his multidisciplinary bowel management clinic. These patients often require multiple complex reconstructive procedures involving urology, orthopaedics and plastic surgery. When care is transitioned into adulthood, Dr. Nasr and his team provide extensive longitudinal follow-up.

Dr. Nasr also specializes in the advanced treatment of trauma and critical care injuries among children. As director of the Johns Hopkins Children’s Center Pediatric Trauma Program — the only pediatric Level 1 trauma center in Maryland — Dr. Nasr leads a large multidisciplinary team that includes staff members from the emergency department, pediatric intensive care, pediatric surgery, physical therapy and child psychology. He successfully led the team three times through the Maryland Institute for Emergency Medical Services Systems accreditation process.

Dr. Nasr’s basic science research interests include studying the gut-brain axis and the inflammatory response following traumatic brain injury in the pediatric population. His clinical focus will be on implementing system-based methods to improve the care of the pediatric trauma patient.

Research Interests

gut-brain axis and the inflammatory response following traumatic brain injury in the pedaitric population.

Selected Publications

  • Baddoura FK, Nasr IW, Wrobel B, Ruddle NH, Lakkis FG. Lymphoid neogenesis in murine cardiac allografts undergoing chronic rejection. American Journal of Transplantation. 2005;5(3): 510-516.

  • Dai Z, Nasr IW, Reel M, Smith-Diggs L, Larsen CP, Rothstein DM, Lakkis FG. Impaired recall of CD8 memory T cells in immunologically privileged tissue. Journal of Immunology. 2005;174(3):1165-70. 

  • Hautz T, Zelger BG, Nasr IW, Mundinger GS, Barth RN, Rodriguez ED, Brandacher G, Weissenbacher A, Zelger B, Cavadas P, Margreiter R, Lee WP, Pratschke J, Lakkis FG, Schneeberger S. Lymphoid neogenesis in skin of human hand, nonhuman primate, and rat vascularized composite allografts. Transplant International. 2014;27(9):966-76 

  • Jindal R, Sucher R, Wang Y, Weinstock M, Pulikkottil BJ, Nasr IW, Zanoun R, Brandacher G. the Immunoregulatory Role of CD200 in Composite Tissue Allotransplantation. Plastic and Reconstructive Surgery. 2010;125(6):32.

  • Nasr IW *, Walker WE*, Camirand G, Tesar BM, Booth CJ, Goldstein DR. (*Co-first Authors) Absence of Innate MyD88 Signaling Promotes Inducible Allograft Acceptance. Journal of Immunology. 2006;177(8):5307-16

  • Nasr IW, Reel M, Oberbarnscheidt MH, Mounzer RH, Baddoura FK, Ruddle NH, Lakkis FG. Tertiary lymphoid tissues generate effector and memory T cells that lead to allograft rejection. American Journal of Transplantation. 2007;7(5):1071-9 

  • Nasr IW, Wang Y, Deng S, Li Q, Smith-Diggs L, Rothstein DM, Tellides G, Lakkis FG, Dai Z. Testicular Immune Privilege Promotes Transplantation Tolerance by Tipping the Balance Between Pathogenic Memory and Regulatory T Cells. Journal of Immunology. 2005;174 (10): 6161-68.

  • Saade NE, Nasr IW, Massaad CA, Safieh-Garabedian B., Jabbur SJ, Kanaan SA. Modulation of ultraviolet-induced hyperalgesia and cytokine upregulation by interleukins 10 and 13.  British Journal of Pharmacology. 2000;131(7):1317-24.

Honors

  • Young Investigator Award for the American Transplant Congress (ATC), American Transplant Congress (ATC), 9/2/07
  • Research Scholarship Award, American College of Surgeons, 5/3/06
  • Distinguished Fellows Research Forum Travel Award, American Society of Transplantation, 1/1/02

Memberships

  • American Pediatric Surgical Association
  • Pediatric Trauma Society
  • American Pediatric Surgical Association, Trauma Committee

Locations

  1. Rubenstein Child Health Building
    • 200 North Wolfe Street, Rubenstein BLDG Lower Level, Baltimore, MD 21287
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Expertise

Education

  • Fellowship: University of Pittsburgh Medical Center, Pediatric Surgery, 2015
  • Fellowship: University of Pittsburgh Medical Center, Pediatric Surgical Critical Care, 2013
  • Residency: University of Pittsburgh Medical Center, General Surgery, 2012
  • Medical Education: American University of Beirut Faculty of Medicine, MD, 2003

Board Certifications

  • Pediatric Surgery: American Board of Surgery, 2016
  • Surgical Critical Care: American Board of Surgery, 2014
  • Surgery (General Surgery): American Board of Surgery, 2013

Insurance

Please contact the location directly to confirm your health plan is accepted.
Search plans
  • Aetna
  • CareFirst
  • Cigna
  • First Health
  • Geisinger Health Plan
  • HealthSmart/Accel
  • Johns Hopkins Health Plans
  • MultiPlan
  • Pennsylvania's Preferred Health Networks (PPHN)
  • Point Comfort Underwriters
  • Private Healthcare Systems (PHCS)
  • Veteran Affairs Community Care Network (Optum-VACCN)