Heba Mostafa, PhD, MBBCh

Highlights

Languages

English

Gender

Female

Johns Hopkins Affiliations:

Johns Hopkins School of Medicine Faculty

About Heba Mostafa

Professional Titles

Division Director, Medical Microbiology
Director, Molecular Virology and Infectious Disease
Director, Infectious Disease Sequencing
Affiliate Faculty, the Armstrong Institute for Patient Safety and Quality

Primary Academic Title

Associate Professor of Pathology

Background

Dr. Heba Mostafa is an Associate Professor of Pathology at the Johns Hopkins University School of Medicine and serves as Director of the Microbiology Division and the Molecular Infectious Diseases Laboratory at The Johns Hopkins Hospital. She is an internationally recognized clinical microbiologist and molecular virologist with expertise in molecular diagnostics, genomic surveillance, infectious disease sequencing, and emerging viral pathogens. Dr. Mostafa also directs the Infectious Disease Sequencing Laboratory and the Microbiology Biocontainment Unit at Johns Hopkins.

Dr. Mostafa earned her M.B.B.Ch. from Alexandria University in Egypt and her Ph.D. in Microbiology from the University of Kansas. She completed a CPEP fellowship and clinical microbiology training at the University of Rochester Medical Center.

Her research focuses on molecular diagnostics, respiratory viruses, including SARS-CoV-2, influenza, enteroviruses, and genomic epidemiology. She has authored more than 125 peer-reviewed publications and has contributed extensively to the development and evaluation of diagnostic assays and genomic surveillance programs. Dr. Mostafa currently serves as President-Elect of the Pan American Society for Clinical Virology and holds different editorial leadership roles including the manual of clinical microbiology, and the Journal of Clinical Virology.

Research Interests

Genomic surveillance of viruses and the correlation between viral evolution and disease severity. Understanding the respiratory virome and developing personalized molecular diagnostic panels for immunocompromised populations. Implementing innovative molecular diagnostics in the clinical microbiology laboratory

PubMed - Publications

https://www.ncbi.nlm.nih.gov/myncbi/heba.mostafa.3/bibliography/public/

Selected Publications

Amary Fall, Raghda E Eldesouki, Jaiprasath Sachithanandham, C Paul Morris, Julie M Norton, David C Gaston, Michael Forman, Omar Abdullah, Nicholas Gallagher, Maggie Li, Nicholas J Swanson, Andrew Pekosz, Eili Y Klein, Heba H Mostafa. The displacement of the SARS-CoV-2 variant Delta with Omicron: An investigation of hospital admissions and upper respiratory viral loads. EBioMedicine. 2022 Apr 20;79:104008. doi: 10.1016/j.ebiom.2022.104008
C. Paul Morris, Chun Huai Luo, Jaiprasath Sachithanandham, Maggie Li, Matthew Schwartz, David C Gaston, Victoria Gniazdowski, Nicolas Giraldo-Castillo, Adannaya Amadi, Julie M Norton, William F Wright, Eili Y Klein, Andrew Pekosz and Heba H Mostafa. Large Scale SARS-CoV-2 Molecular Testing and Genomic Surveillance Reveal Prolonged Infections, Protracted RNA shedding, and Viral Reinfections
Katharine Uhteg, Adannaya Amadi, Michael Forman, Heba H Mostafa. Circulation of Non- SARS-CoV-2 Respiratory Pathogens and Coinfection with SARS-CoV-2 Amid the COVID-19 Pandemic. Open Forum Infect Dis. 2021 Dec 8;9(3):ofab618. doi: 10.1093/ofid/ofab618
Luo CH, Morris CP, Sachithanandham J, Amadi A, Gaston D, Li M, Swanson NJ, Schwartz M, Klein EY, Pekosz A, Mostafa HH. Infection with the SARS-CoV-2 Delta Variant is Associated with Higher Recovery of Infectious Virus Compared to the Alpha Variant in both Unvaccinated and Vaccinated Individuals. Clin Infect Dis. 2021 Dec 18:ciab986. doi: 10.1093/cid/ciab986. Online ahead of print. PMID: 34922338
Morris CP, Luo CH, Amadi A, Schwartz M, Gallagher N, Ray SC, Pekosz A, Mostafa HH. An Update on SARS-CoV-2 Diversity in the United States National Capital Region: Evolution of Novel and Variants of Concern. Clin Infect Dis. 2021 Jul 17:ciab636. doi: 10.1093/cid/ciab636. Online ahead of print. PMID: 34272947