Hanghang Wang, MD, PhD

Primary Academic Title

Assistant Professor of Cardiac Surgery

Background

Videos

• Meet Our Expert: Dr. Hanghang Wang
• Mitral Valve Disease | FAQ
• Red Chair Series with Dr. Hanghang Wang: Understanding Cardiovascular Disease in Women
• Red Chair Series with Dr. Hanghang Wang: The Future of Medicine

Recent News Articles and Media Coverage

• Community DC: Jenni Chase & American Heart Association | Community DC Podcast (February 2025)
• At Suburban Hospital, Cardiac Surgery Expertise Shines | Johns Hopkins Medicine (March 2025)
• Intersession Program in Cardiac Surgery | Johns Hopkins Video Feature, Facebook (February 2, 2026)

Contact for Research Inquiries

The Cardiovascular Precision Medicine Laboratory

Research Interests

Artificial Intelligence, Bioengineering, Computational Biology, Machine Learning, Omics, Precision Medicine

Lab Website

Cardiovascular Precision Medicine Laboratory - Lab Website

• The Cardiovascular Precision Medicine Laboratory led by Dr. Hanghang Wang operates at the intersection of cardiac surgery, computational biology, and bioengineering. With a focus on precision medicine, we are dedicated to creating personalized diagnostic and treatment modalities for cardiovascular diseases, integrating cutting-edge research into clinical practice. Our laboratory is also an integral component of the Broccoli Aortic Center for Aortic Diseases, further enhancing our research capabilities and clinical impact.

Google Scholar - Publications

https://scholar.google.com/citations?hl=en&user=9vHWog4AAAAJ

PubMed - Publications

https://www.ncbi.nlm.nih.gov/myncbi/hanghang.wang.1/bibliography/public/

Research Gate - Research Profile

https://www.researchgate.net/profile/Hanghang-Wang-6

Selected Publications

• Wang H and Gammie JS. Surgical Techniques for Mitral Valve Repair: A Review for the Non-Cardiac Surgeon. Current Cardiology Reports. 2025; 27(1): 60; doi: 10.1007/s11886-025-02213-y. PubMed PMID: 39992440

• Wang H, Dun C, Makary MA, Walsh C, Fan Y, Rodriguez E, Patel D, Zhou A, Akbar A, Whitman G, Gammie JS. Wide variation in mitral valve repair rates among US surgeons: Analysis of Medicare claims data. The Journal of Thoracic and Cardiovascular Surgery. 2024; Oct 25:S0022-5223(24)00986-3; doi: 10.1016/j.jtcvs.2024.10.035. PubMed PMID: 39461413

• Hahn VS, Petucci C, Kim MS, Bedi KC Jr, Wang H, Mishra S, Koleini N, Yoo EJ, Margulies KB, Arany Z, Kelly DP, Kass DA, Sharma K. Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction. Circulation. 2023 Apr 11;147(15):1147-1161. doi: 10.1161/CIRCULATIONAHA.122.061846. Epub 2023 Mar 1. PubMed PMID: 36856044.

• Wang H, Wagner M, Benrashid E, Keenan J, Wang A, Ranney D, Yerokun B, Gaca JG, McCann RL, Hughes GC. Outcomes of Reoperation After Acute Type A Aortic Dissection: Implications for Index Repair Strategy. J Am Heart Assoc. 2017 Oct 3;6(10). doi: 10.1161/JAHA.117.006376. PubMed PMID: 28974497

• Wang H, Anstrom K, Ilkayeva O, Muehlbauer MJ, Bain JR, McNulty S, Newgard CB, Kraus WE, Hernandez A, Felker GM, Redfield M, Shah SH. Sildenafil Treatment in Heart Failure With Preserved Ejection Fraction: Targeted Metabolomic Profiling in the RELAX Trial. JAMA Cardiol. 2017 Aug 1;2(8):896-901. doi: 10.1001/jamacardio.2017.1239. PubMed PMID: 28492915

Honors

• Top Doctor 2025, Washingtonian
• 2025 AATS James L. Cox Fellowship in Atrial Fibrillation Surgery
• AATS Leadership Academy, 2023
• AATS Foundation Honoring Our Cleveland Clinic Mentors Leadership Program, 2022
• AATS Foundation Thoracic Surgical Robotics Fellowship, 2021 - 2022
• AHA FGTB Young Investigator Abstract Travel Award, 2016
• Thoracic Surgery Foundation for Research and Education Braunwald Fellowship, 2015 - 2017
• NIH T32 National Research Service Award, NIH, 2015 - 2017
• Women in Thoracic Surgery (WTS) Scholarship, 2010
• Summer Fellowship, Memorial Sloan Kettering Cancer Center, 2009
• AATS Summer Scholarship, 2009
• Summer Scholar in Thoracic Surgery, Massachusetts General Hospital, 2008
• Outstanding Commitment to Community Service, Grinnell College, 2007
• Smith Family Award in Biology, Grinnell College, 2007
• Joseph F. Wall Scholarship, Grinnell College, 2006
• High Academic Achievement, Institute for the International Education of Students, 2006
• Berlin Minority Scholarship, Institute for the International Education of Student, 2006

Lectures & Presentations

• “Mitral Valve Repair and Outcomes”, Nazareth Hospital Cardiology Grand Rounds, Philadelphia, PA; Mar 2025
• “Artificial Intelligence and Digital Health”, 23rd Annual Women’s Symposium, Johns Hopkins Hospital, Baltimore, MD; Feb 2025
• “Metabolomic Insights into Cardiometabolic Health: Bridging Molecular Mechanisms & Clinical Care”, Visiting Professor, Center for Global Cardiometabolic Health & Nutrition, UC Irvine, CA; Jan 2025
• “Wide Variation in Mitral Valve Repair Rates Among U.S. Surgeons: Analysis of Medicare Claims Data”, Western Thoracic Surgical Association Annual Meeting, Vail, CO; Jun 2024
• “Precision Medicine in Motion: The Ballet of Mitral Valve Repair”, Suburban Hospital Johns Hopkins Medicine Grand Rounds, Bethesda, MD; Jun 2024
• "The Heart of Resilience: Empowering Lifelong Cardiovascular Wellness", US Army Public Health Command, East, Ford Meade, MD; Apr 2024
• “Educating Surgeons of Tomorrow: A Johns Hopkins Odyssey”, Xiangyang Central Hospital Grand Rounds, Xiangyang, China; Apr 2024
• “Pioneering to Personalization: The Evolution of Cardiac Surgery at Johns Hopkins”, Beijing Luhe Hospital, Beijing, China; Apr 2024
• “AI and Medicine: The Transformative Role of Artificial Intelligence in Healthcare”, Johns Hopkins Development & Alumni Relations Talent Conference, Bethesda, MD; Apr 2024
• "Artificial Intelligence and Aortic Disease", International Aortic Disease Forum, Nanjing, China; Sep 2023
• “Identification of Novel Molecular Pathways and Mechanisms in Renal Disease” Nephrology Grand Rounds, Duke University Medical Center, Durham, NC; May 2017

Memberships

• Society of Thoracic Surgeons (STS), Selected Member of STS Workforce on Research 
• Society of Thoracic Surgeons (STS), Selected Member of STS Workforce on Database Innovations
• American Heart Association (AHA), Selected Member of AHA CVSA Early Career Committee
• Maryland Cardiac Surgery Quality Initiative (MCSQI), Chair of Quality Committee
• Southern Thoracic Surgical Association (STSA)
• Women in Thoracic Surgery (WTS)
• The Robert J. Lefkowitz Society at Duke Medicine
• Dartmouth-Mosenthal Surgical Society
• Phi Beta Kappa Honor Society

Professional Activities

• Program Director, Summer Research Program in Cardiac Surgery for Medical Students, Johns Hopkins Hospital
• Program Director, in Cardiac Surgery for Undergraduates, Johns Hopkins Hospital
• Course Director, Cardiac Surgery Curriculum for Advanced Practitioners, Johns Hopkins Suburban Hospital
• Faculty Mentor, MPH Program, Johns Hopkins University School of Medicine 
• Faculty Member, Center for Artificial Intelligence, Innovation Research & Equity (CAIIRE), MGH, Boston, MA
• Faculty Mentor, Woodrow Wilson Fellows Program, Johns Hopkins University