
Gene Y. Fridman, MS, PhD
Highlights
Languages
- English
Gender
MaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Gene Y. Fridman
Primary Academic Title
Professor of Otolaryngology-Head and Neck Surgery
Background
Gene Fridman is a researcher in bioinstrumentation and neural engineering, specializing in neural implants. His lab is the Machine Biointerface Laboratory.
The key focus of Dr. Fridman’s research is Freeform stimulation technology. This neural implant allows a more natural modulation of neural activity — both toward excitation and toward inhibition — than is currently possible with conventional implantable devices such as cochlear implants, spinal cord stimulators and deep brain stimulators.
After receiving his master’s degree in electrical engineering from Purdue University, Dr. Fridman worked as a software and systems engineer in the industry before engaging in an academic career. He earned his doctoral degree in biomedical engineering, specializing in neural recording and stimulation and microelectromechanical systems (MEMS), from UCLA. He has ongoing consulting relationships with several biomedical engineering companies in research and design of neural stimulation and recording devices, and has contributed to research and development of retinal, cortical, cochlear and vestibular implants.
Recent News Articles and Media Coverage
Additional Academic Titles
Professor of Biomedical Engineering
Research Interests
Medical Instrumentation, Neural prostheses, Vestibular and Cochlear implants
Lab Website
Fridman Lab - Lab Website
Google Scholar - Publications
Selected Publications
Fridman GY, Della Santina CC, “Safe Direct Current Stimulator 2: Concept and Design”, IEEE EMBC 2013 Conference Paper
Valentin NS, Hageman K, Dai C, Della Santina CC, Fridman GY, “Development of a Multichannel Vestibular Prosthesis Prototype by Modification of a Commercially Available Cochlear Implant, IEEE Trans Neural Syst Rehabil Eng. 2013 May 1. [Epub ahead of print] PubMed PMID: 23649285
Fridman GY, Della Santina CC, “Safe Direct Current Stimulation to Expand Capabilities of Neural Prostheses”, IEEE Trans Neural Syst Rehabil Eng. 2013 May 1. [Epub ahead of print] PubMed PMID: 23649285
Davidovics NS, Rahman MA, Dai C, Ahn JH, Fridman GY, Della Santina CC, “Multichannel Vestibular Prosthesis Employing Modulation of Pulse Rate and Current with Alignment Precompensation Elicits Improved VOR Performance in Monkeys”, J Assoc Res Otolaryngol. 2013 Apr;14(2):233-48. doi: 10.1007/s10162-013-0370-7. Epub 2013 Jan 26. PubMed PMID: 23355001; PubMed Central PMCID: PMC3660911
Fridman GY, Della Santina CC., “Progress toward development of a multichannel vestibular prosthesis for treatment of bilateral vestibular deficiency.”, Anat Rec (Hoboken). 2012 Nov;295(11):2010-29. doi: 10.1002/ar.22581. Epub 2012 Oct 8
Davidovics NS, Fridman GY, Della Santina CC., “Co-modulation of stimulus rate and current from elevated baselines expands head motion encoding range of the vestibular prosthesis.”, Exp Brain Res. 2012 May;218(3):389-400. doi: 10.1007/s00221-012-3025-8. Epub 2012 Feb 19.
Sun D.Q., Rahman MA, Fridman GY, Chiang B, Dai C, Della Santina CC, “Chronic Stimulation of the Semicircular Canals Using a Multichannel Vestibular Prosthesis: Effects on Locomotion and Angular Vestibulo-Ocular Reflex in Chinchillas”, Conf. Proc. IEEE 33rd Annual EMBC Conference, Boston, MA 2011
Rahman MA, Dai C, Fridman GY, Davidovics NS, Chiang B, Ahn JH, Hayden R, Melvin TN, Sun DQ, and Della Santina CC, “Restoring the 3D Vestibulo-Ocular Reflex via Electrical Stimulation: The Johns Hopkins Multichannel Vestibular Prosthesis Project” Conf. Proc. IEEE 33rd Annual EMBC Conference, Boston, MA 2011
Dai, C, Fridman GY, Chiang B, Davidovics NS, Melvin TA, Cullen KE, Della Santina CC, “Cross-axis adaptation improves 3D vestiblulo-ocular reflex alignment during chronic stimulation via a head-mounted multichannel vestibular prosthesis”, Exp Brain Res. 2011 May;210(3-4):595-606. Epub 2011 Mar 4.
Chiang B, Fridman G, Dai C, Della Santina C, “Design and performance of a multichannel vestibular prosthesis that restores semicircular canal sensation in macaques.”, IEEE Trans Neural Syst Rehabil Eng. 2011 Oct;19(5):588-98. Epub 2011 Aug 18.
Dai C, Fridman GY, Della Santina CC. “Effects of Vestibular Prosthesis Electrode Implantation and Stimulation on Hearing in Rhesus Monkey”, Hear Res. 2011 Jul;277(1-2):204-10. Epub 2010 Dec 31.
Della Santina CC, Migliaccio AA, Hayden R, Melvin TA, Fridman GY, Chiang B, Davidovics NS, Dai C, Carey JP, Minor LB, Anderson ICW, Park H, Lyford-Pike S, Tang S, “Current and Future Management of Bilateral Loss of Vestibular Sensation – An update on the Johns Hopkins Multichannel Vestibular Prosthesis Project,”Cochlear Implants International 2010 Sept 11(s2): 2-11.
Davidovics NS, Fridman GY, Chiang B, Della Santina CC, “Effects of biphasic current pulse frequency, amplitude, duration and interphase gap on eye movement responses to prosthetic electrical stimulation of the vestibular nerve”, IEEE Trans Neural Syst Rehabil Eng. 2011 Feb;19(1):84-94. Epub 2010 Sep 2.
Fridman GY., Davidovics NS, Dai CC, Migliaccio AA, Della Santina CC “Vestibulo-Ocular Reflex Responses to a Multichannel Vestibular Prosthesis Incorporating a 3D Coordinate Transformation for Correction of Misalignment”, J Assoc Res Otolaryngol. 2010 Sep;11(3):367-81. Epub 2010 Feb 23.
Fridman GY, Blair HT, Blaisdell AP, Judy JW. “Perceived intensity of somatosensory cortical electrical stimulation”, Exp Brain Res. 2010 Jun; 203(3):499-515.
Jacobs AL, Fridman GY, Douglas RM, Alam NJ, Latham PE, Prusky GT, Nirenberg S, (2009) “Ruling Out and Ruling in Neural Codes”, Proceedings of the National Academy of Science 106 (14): 5936-5941 April 7, 2009
Litvak LM, Spahr AJ, Saoji AA, Fridman GY, (2007) “Relationship Between Perception of Spectral Ripple and Speech Recognition in Cochlear Implant and Vocoder Listeners”, Journal of the Acoustical Society of America 122 (2): 982-991 AUG 2007
Fridman GY, Blair HT, Blaisdell AP, Judy JW, “Somatosensory Feedback to Improve Brain-Machine Interfaces: Stimulation Studies in Rat Whisker Barrel Somatosensory Cortex”, 2007 3rd International IEEE/EMBS Conference on Neural Engineering, Vols 1 and 2 Pages: 379-385
Honors
- Neurobiology Retreat Best Paper Award, UCLA, 1/1/03
- Al Mann Engineer of the Year Award Advanced, Bionics Corp, 1/1/98
Lectures & Presentations
- A Biophysical Model for the Perceived Intensity of Cortical Electrical Stimulation, BMES, Los Angeles, CA, 8/6/14
- Addition of Chronic Direct Current Stimulation Improves Vestibular Prosthesis Dynamic Range, Assoc. Research in Otolaryngology Mid Winter Meeting, San Diego, CA, 8/6/14
- Design and Development for Cochlear and Vestibular Implants, Presentation, 11th Software Design for Medical Devices Annual Meeting, San Diego, CA, 8/6/14
- Frequency discrimination of artificial brain stimulation delivered to whisker barrel cortex in rats, Society for Neuroscience, Atlanta, GA, 8/6/14
- Give Haptics A Hand, 41st Annual Winter Conference on Brain Research, Snow Bird, UT, 8/6/14
- Information Theory Analysis of Retinal Response to Flash Stimuli, Neuroscience/Neuroengineering Retreat, Los Angeles, CA, 8/6/14
- Linearity of the 3-D Vestibulo-Ocular Reflex Response to Electrical Stimulation, BMES, St. Louis, MO, 8/6/14
- Neural Engineering Workshop, Cleveland, OH, 8/6/14
- Safe Direct Current Neural Implant, Design of Medical Devices Conference, University of Minnesota, 8/6/14
- Safe Direct Current Stimulation System to Improve Vestibular Prosthesis Performance, BMES, Osaka, Japan, 8/6/14
- Safe Direct Current Stimulation to Expand Capabilities of Neural Prostheses, ICNPD-2012, Freiburg, Germany, 8/6/14
- Solutions to Problem of Electrode Channel Interaction in a Vestibular Prosthesis, BMES, Austin, TX, 8/6/14
- Understanding Evolving Technology for Cochlear and Vestibular Implants, Medical Devices Regulation and Compliance Meeting, Boston, MA, 8/6/14
Memberships
- Association for Research in Otolaryngology (ARO)
- Institute for Electrical And Electronics Engineers (IEEE)
Professional Activities
- IEEE, Reviewer
- JARO, Reviewer
- TBIOCAS, Reviewer
Additional Training
Johns Hopkins University, Baltimore, MD, 2009, Neuroengineering applied to the Vestibular System
Expertise
Education
- David Geffen School of Medicine at UCLA, Ph.D., 2006
- Purdue University, M.S., 1994
- University of Kansas, B.S., 1992