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Eellan Sivanesan

Eellan Sivanesan, MD

Pain MedicineAnesthesiology

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Highlights

Age Groups Seen

  • Infant 0-2
  • Child 3-12
  • Adolescent 13-17
  • Young Adult 18-25
  • Adult 26-64
  • Older Adult 65+

Languages

  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Eellan Sivanesan

Physician’s Office Phone

410-955-7246

Physician’s Office Fax

410-367-2047

Professional Titles

  • Director of Neuromodulation - Pain Medicine Division

Primary Academic Title

Associate Professor of Anesthesiology and Critical Care Medicine

Johns Hopkins Physician

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Background

Dr. Eellan Sivanesan serves as the Director of Neuromodulation and an Associate Professor in the Department of Anesthesiology and Critical Care Medicine at the Johns Hopkins University School of Medicine. He is a Johns Hopkins expert in complex pain, cancer-related pain, and neuromodulation whose clinical and research work focuses on developing and advancing treatments for patients suffering from severe chronic pain, cancer-related pain, nerve injury, and chemotherapy-induced peripheral neuropathy. His clinical practice includes the full spectrum of advanced pain management, including medication management, image-guided procedures, minimally invasive spine procedures, and neuromodulation therapies such as spinal cord stimulation, dorsal root ganglion stimulation, peripheral nerve stimulation, and intrathecal drug delivery. He treats patients with complex pain conditions at the Johns Hopkins Blaustein Pain Treatment Center, with a focus on patients who have not responded to traditional treatments. Patients seek his expertise from across the United States and internationally for complex pain conditions, cancer pain, and advanced pain therapies. His research program at Johns Hopkins focuses on developing new treatments for chronic pain and cancer-related pain, and philanthropic support helps advance this research and clinical trials for patients suffering from these conditions.

In addition to complex neuromodulation cases, Dr. Sivanesan treats a wide range of pain conditions at the Blaustein Pain Treatment Center, including chronic back, joint, abdominal, pelvic, facial, and headache pain, as well as neuropathic pain, cancer-related pain, complex regional pain syndrome (CRPS), and post-amputation pain. His clinical expertise includes advanced image-guided procedures using fluoroscopy and ultrasound to target the spine, peripheral nerves, muscles, and joints. He also performs radiofrequency ablation, chemodenervation (such as botulinum toxin injections), and neurolytic procedures to relieve severe or cancer-related pain when appropriate.

Dr. Sivanesan specializes in advanced neuromodulation and minimally invasive spine procedures to manage complex chronic pain conditions. He is frequently invited to speak nationally and internationally on neuromodulation, minimally invasive spine procedures, and cancer-related pain. His expertise includes spinal cord stimulation, dorsal root ganglion (DRG) stimulation, peripheral nerve stimulation, craniofacial stimulation, basivertebral nerve ablation (Intracept), vertebral augmentation procedures (such as vertebroplasty, kyphoplasty, and SpineJack), and intrathecal drug delivery. He has introduced numerous new pain treatment modalities to The Johns Hopkins Health System, including minimally invasive lumbar decompression, interspinous spacers, temporary peripheral nerve stimulation, closed-loop spinal cord stimulation, wireless spinal cord and peripheral nerve stimulation, restorative neurostimulation, and multiple other neuromodulation and minimally invasive spine advancements.

Dr. Sivanesan serves in editorial leadership roles for Regional Anesthesia and Pain Medicine, Pain Medicine (Section-Neuromodulation and Minimally Invasive Spine), Neuromodulation, and Molecular Pain. He has also served as an invited ad hoc reviewer for NIH study sections in pain and neuromodulation. In addition, he serves as core faculty for clinician-scientist and interdisciplinary pain research training programs at Johns Hopkins and participates in committees of the International Neuromodulation Society (INS), the American Society of Regional Anesthesia and Pain Medicine (ASRA), the International Association for the Study of Pain (IASP), and the North American Neuromodulation Society (NANS).

Dr. Sivanesan’s neuromodulation and cancer pain research, conducted through the Sivanesan Neuromodulation Laboratory at Johns Hopkins, is focused on developing new treatments to help patients suffering from severe chronic pain, nerve injury, and cancer-related pain. He has received research funding from the National Cancer Institute and the National Institutes of Health, as well as other national foundations, to study neuromodulation and cancer-related pain. His laboratory is particularly interested in the use of targeted electrical stimulation, including spinal cord stimulation, for painful chemotherapy-induced peripheral neuropathy and cancer-related pain. His work has been published in The Lancet, Anesthesiology, Neuromodulation, Pain, Regional Anesthesia and Pain Medicine, The British Journal of Anaesthesia, Journal of Clinical Anesthesia, Infection Control & Hospital Epidemiology, Journal of Pain & Palliative Care Pharmacotherapy, Pain Reports, Pain Medicine, Anesthesia and Analgesia, Neuroscience Bulletin, and Molecular Pain, and featured on the covers of Anesthesia & Analgesia and Neuromodulation. Philanthropic support helps advance research, clinical trials, and innovative treatments for patients suffering from chronic pain, nerve injury, and cancer-related pain.

Education: After graduating from The University of Oklahoma with a dual bachelor of science in Biochemistry and Zoology, Dr. Sivanesan completed medical school at The University of Oklahoma College of Medicine. He then completed an anesthesiology residency (clinical scientist track) and pain medicine fellowship at The University of Miami Miller School of Medicine, followed by a National Institutes of Health postdoctoral research fellowship for clinician-scientists. Dr. Sivanesan has received research awards from the National Cancer Institute, National Institutes of Health, the Jacob and Hilda Blaustein Foundation, the American Society of Regional Anesthesia and Pain Medicine (ASRA), the Thompson Family Foundation, and the Foundation for Anesthesia Education and Research (FAER).

Contact Dr. Eellan Sivanesan

Johns Hopkins Blaustein Pain Treatment Center
Johns Hopkins Outpatient Center
601 North Caroline Street, Suite 3062
Baltimore, MD 21287

Appointment Information: 410-955-PAIN (7246)
Phone: 410-955-7246
Fax: 410-367-2047

Directions: Directions to the Outpatient Center

Centers and Institutes

Clinical Trial Keywords

Neuromodulation; Spinal Cord Stimulation; Dorsal Root Ganglion Stimulation; Peripheral Nerve Stimulation; Intrathecal Drug Delivery; Cancer Pain; Chemotherapy-induced Peripheral Neuropathy; Peripheral Neuropathy; Neuropathic Pain; Complex Regional Pain Syndrome; Post-Amputation Pain; Electrical Stimulation Therapy; Translational Pain Research

Contact for Research Inquiries

Dr. Eellan Sivanesan
Johns Hopkins Blaustein Pain Treatment Center
Johns Hopkins Outpatient Center
601 North Caroline Street, Suite 3062
Baltimore, MD 21287

Research Interests

Cancer Pain, Chemotherapy-induced Peripheral Neuropathy, Complex Regional Pain Syndrome (CRPS), Dorsal Root Ganglion (DRG) Stimulation, Intrathecal Drug Delivery, Neuromodulation-Spinal Cord Stimulation, Peripheral Nerve Stimulation

Lab Website

Sivanesan Neuromodulation Laboratory (SNL) - Lab Website

  • Funded by the National Cancer Institute, National Institutes of Health, Dr. Sivanesan’s neuroscience research at Johns Hopkins aligns with his clinical practice as he investigates the effects of spinal cord stimulation and other neuromodulation therapies. His laboratory is particularly interested in the use of neuromodulation for cancer pain and chemotherapy-induced peripheral neuropathy. Work in the Sivanesan Neuromodulation Laboratory focuses on developing electrical stimulation therapies for treating neuropathic pain conditions and discovering novel applications for patients suffering from painful conditions. Philanthropic support for the Sivanesan Neuromodulation Laboratory helps accelerate research, support trainees, and develop new therapies for patients suffering from chronic pain, nerve injury, and cancer pain.

Research Summary

Dr. Sivanesan’s research program focuses on neuromodulation and translational neuroscience, particularly the use of spinal cord stimulation and other electrical stimulation therapies for chronic pain, cancer-related pain, and chemotherapy-induced peripheral neuropathy. His laboratory studies the mechanisms by which neuromodulation alters pain signaling, neuroimmune interactions, and peripheral nerve injury, with the goal of developing new stimulation therapies and improving outcomes for patients with neuropathic and cancer-related pain. His work spans basic science, translational research, and clinical studies evaluating neuromodulation therapies.

Selected Publications

  • Neuromodulation for chronic pain. The Lancet. 2021.
  • Spinal Cord Stimulation Increases Chemoefficacy and Prevents Paclitaxel-Induced Pain via CX3CL1. Neuromodulation. 2023.
  • Spinal Cord Stimulation Attenuates Paclitaxel-Induced Gait Impairment and Mechanical Hypersensitivity. Regional Anesthesia and Pain Medicine. 2025.
  • Supraspinal mechanisms of spinal cord stimulation for modulation of pain: Five decades of research. Anesthesiology. 2018.
  • A Definition of Neuromodulation and Classification of Implantable Electrical Modulation for Chronic Pain. Neuromodulation. 2024.

Honors

  • Extramural Program Award for Clinical Researchers, National Cancer Institute, National Institutes of Health
  • Clinical Scientist Award, National Cancer Institute, National Institutes of Health
  • Research Award, Foundation for Anesthesia Education and Research (FAER)
  • Chronic Pain Medicine Research Award, American Society of Regional Anesthesia and Pain Medicine (ASRA)
  • Stimulating and Advancing ACCM Research (StAAR) Investigator Award, Johns Hopkins University School of Medicine
  • Blaustein Pain Research Award, Johns Hopkins University School of Medicine

Lectures & Presentations

Dr. Sivanesan is a nationally and internationally invited speaker on neuromodulation, cancer-related pain, and minimally invasive spine procedures. He has presented invited lectures at the American Society of Anesthesiologists Annual Meeting, the American Society of Regional Anesthesia and Pain Medicine Annual Meeting, the North American Neuromodulation Society Annual Meeting, the International Neuromodulation Society World Congress, the Royal College of Anaesthetists (United Kingdom), the Canadian Neuromodulation Society Annual Meeting, and multiple academic medical centers in the United States and internationally.

Memberships

  • International Neuromodulation Society (INS)
  • North American Neuromodulation Society (NANS)
  • American Society of Regional Anesthesia and Pain Medicine (ASRA)
  • International Association for the Study of Pain (IASP)
  • American Association for Cancer Research (AACR)

Professional Activities

  • Editor, Neuromodulation
  • Associate Editor, Regional Anesthesia and Pain Medicine
  • Associate Editor, Pain Medicine (Neuromodulation and Minimally Invasive Spine Section)
  • Editor, Molecular Pain
  • Invited Ad Hoc Reviewer, National Institutes of Health (NIH) Study Sections and Special Emphasis Panels
  • Core Faculty, Clinician-Scientist Training Program (T32), Johns Hopkins University School of Medicine
  • Core Faculty, Interdisciplinary Training Program in Biobehavioral Pain Research (T32), Johns Hopkins University School of Medicine
  • Chair, Advocacy and Policy Committee Interventional Subcommittee, North American Neuromodulation Society
  • Member, Committee on Research, American Society of Anesthesiologists

Locations

  1. Levi Watkins, Jr., M.D., Outpatient Center
    • 601 North Caroline Street, Suite 3062, Baltimore, MD 21287
    • Get Directions

Expertise

Education

  • Fellowship: University of Miami Jackson Health, Anesthesiology - Pain Medicine, 2017
  • Residency: University of Miami Jackson Health, Anesthesiology, 2016
  • Medical Education: University of Oklahoma College of Medicine, Medicine, MD, 2012

Board Certifications

  • Pain Medicine: American Board of Anesthesiology, 2017
  • Anesthesiology: American Board of Anesthesiology, 2017

Insurance

Please contact the location directly to confirm your health plan is accepted.
Search plans
  • Aetna
  • CareFirst
  • Cigna
  • First Health
  • Geisinger Health Plan
  • HealthSmart/Accel
  • Johns Hopkins Health Plans
  • MultiPlan
  • Pennsylvania's Preferred Health Networks (PPHN)
  • Point Comfort Underwriters
  • Private Healthcare Systems (PHCS)
  • Veteran Affairs Community Care Network (Optum-VACCN)

Ratings & Reviews

4.7 out of 5

60 ratings, 16 reviews

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Overall Rating by Patient
Provider Listened Carefully
Provider Explained Things Clearly
Provider Knew Medical History
Provider Showed Respect
Provider Spent Enough Time
Search reviews
    5 out of 5 stars
    Reviewed on 3/17/2026

    I have been receiving these treatments since 2014. The team is almost always phenomenal. This particular visit was exceptional in every way.

    4 out of 5 stars
    Reviewed on 3/12/2026

    Very knowledgeable

    5 out of 5 stars
    Reviewed on 3/3/2026

    I was referred to the Clinic and I am so happy that I chose Dr. Sivanesan as my Provider. He listened carefully to my concerns, was versed about my history and provided me with his recommendations regarding treatment. Dr. Sivanesan is very kind and skilled and his team are very attentive to patient care and comfort! I am very grateful and plan to express this in follow-up with Dr. Sivanesan.

    5 out of 5 stars
    Reviewed on 2/24/2026

    Professional , good listener seem updated, critical thinker approach to solve my issues knowledgeable Providing a plan

    4 out of 5 stars
    Reviewed on 1/23/2026

    Dr.Eellan Sivanesan is a specialist in his field of Anaesthesiology and Pain Medicine can provide a treatment plan based on his expertise to bring relief to me . This was my ist visit but I didn't have much time with him .

    5 out of 5 stars
    Reviewed on 1/23/2026

    Excellent care and service from all involved.

    5 out of 5 stars
    Reviewed on 1/8/2026

    Good

    5 out of 5 stars
    Reviewed on 1/2/2026

    Dr. Sivanesan is a very skilled provider who listened carefully and recommended a treatment for the specific problems I described. I chose Dr. Sivanesan from the listed providers based on his credentials and I am happy that I chose him!

    5 out of 5 stars
    Reviewed on 12/17/2025

    Very pro forma visit.

    5 out of 5 stars
    Reviewed on 12/11/2025

    I have total respect and appreciation for this doctor.

    5 out of 5 stars
    Reviewed on 10/24/2025

    I feel he was doing what I believed needed to help with my pain

    4 out of 5 stars
    Reviewed on 10/17/2025

    Dr [last name] was very nice. He took guidance from Dr Sivanesan with professionalism

    5 out of 5 stars
    Reviewed on 8/25/2025

    Excellent doc

    5 out of 5 stars
    Reviewed on 7/11/2025

    Very good experience by the doctor and his resident.

    5 out of 5 stars
    Reviewed on 5/27/2025

    Very positive and great

    5 out of 5 stars
    Reviewed on 5/27/2025

    Dr. Sivanesan was excellent.