Chengcheng Gui, MD
Radiation OncologyHead and Neck Radiation Oncology
Highlights
Johns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Chengcheng Gui
Primary Academic Title
Instructor in Radiation Oncology and Molecular Radiation Sciences
Johns Hopkins Physician
Background
Dr. Chengcheng Gui is an instructor in the Department of Radiation Oncology and Molecular Radiation Sciences at the Johns Hopkins University School of Medicine. His clinical focus is the use of radiotherapy to treat head and neck cancers, as well as skin cancers.
Dr. Gui obtained his medical degree from the Johns Hopkins University School of Medicine and completed his residency training at Memorial Sloan Kettering Cancer Center, where he served as chief resident and received the Radiation Oncology Medical Student Teaching Award.
Dr. Gui believes that cancer patients deserve a clear and thorough understanding of the benefits and risks of their treatment options, empowering them to choose the path that best aligns with their personal values. To support this, Dr. Gui is committed to being an approachable, trustworthy source of information, while also planning and delivering high-quality radiotherapy.
Research Summary
Dr. Gui's research focuses on enhancing the safety and effectiveness of radiotherapy by integrating multiple data modalities. His work incorporates advanced structural and functional imaging, tumor molecular characteristics, and patient-reported outcomes to inform and personalize treatment approaches.
Selected Publications
Gui C, Wray R, Schöder H, Deasy JO, Grkovski M, Humm JL, Wong RJ, Sherman EJ, Riaz N, Lee NY. Tumor hypoxia on 18F-fluoromisonidazole positron emission tomography and distant metastasis from head and neck squamous cell carcinoma. JAMA Network Open. 2024 Sep 3;7(9):e2436407-.
Gui C, Walch H, Mueller K, Boe L, Skakodub A, Miao E, Khatri I, Kumar R, Padilla Mazzeo, Shen J, Cooper C, Parker M, Hsu A, Patel R, Ilica AT, Stember JN, Eichholz JE, Bou Nassif R, Yu KKH, Wilcox JA, Manca P, Yu Y, Yamada Y, Imber BS, Maron SB, Foote MB, Chatila WK, Yaeger R, Schultz N, Pike LRG. Genomics correlates of brain metastasis and progression in colorectal cancer. Neuro-Oncology. 2025 Aug 28:noaf198. doi: 10.1093/neuonc/noaf198. Online ahead of print.
Gui C, Vannorsdall TD, Kleinberg LR, Assadi R, Moore JA, Hu C, Quiñones-Hinojosa A, Redmond KJ. A prospective cohort study of neural progenitor cell-sparing radiation therapy plus temozolomide for newly diagnosed patients with glioblastoma. Neurosurgery. 2020 Jul 1;87(1):E31-40.
Redmond KJ, Gui C, Benedict S, Milano MT, Grimm J, Vargo JA, Soltys SG, Yorke E, Jackson A, El Naqa I, Marks LB. Tumor control probability of radiosurgery and fractionated stereotactic radiosurgery for brain metastases. International Journal of Radiation Oncology* Biology* Physics. 2021 May 1;110(1):53-67.
Eitz KA, Lo SS, Soliman H, Sahgal A, Theriault A, Pinkham MB, Foote MC, Song AJ, Shi W, Redmond KJ, Gui C, Kumar AMS, Machtay M, Meyer B, Combs SE. Multi-institutional analysis of prognostic factors and outcomes after hypofractionated stereotactic radiotherapy to the resection cavity in patients with brain metastases. JAMA Oncology. 2020 Dec 1;6(12):1901-9.
Locations
- Sidney Kimmel Comprehensive Cancer Center
- 401 North Broadway Street, Weinberg BLDG, Floor-L1 (Lobby Level), Baltimore, MD 21287
- Get Directions
- phone: 410-502-8000
- fax: 410-502-1419
- Sidney Kimmel Comprehensive Cancer Center
- 401 North Broadway Street, Weinberg Building, Floor-L2, Baltimore, MD 21287
- Get Directions
- phone: 410-502-8000
- fax: 410-502-1419
Expertise
Education
- Residency: Memorial Sloan-Kettering Cancer Center, Radiation Oncology, 2025
- Medical Education: Johns Hopkins University School of Medicine, MD, 2020
Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- Veteran Affairs Community Care Network (Optum-VACCN)
Ratings & Reviews
5 out of 5
32 ratings, 14 reviewsThe Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
- 5 out of 5 starsReviewed on 3/16/2026
I'm very happy to have the excellent care I receive from the team at Johns Hopkins.
- 5 out of 5 starsReviewed on 3/6/2026
Very pleasant and competent. Very thorough in explaining my condition and treatment options. Answered all our questions thoroughly and patiently.
- 5 out of 5 starsReviewed on 2/27/2026
Very courteous
- 5 out of 5 starsReviewed on 2/23/2026
Very patient, does not rush me through my questions, and explains everything fully.
- 5 out of 5 starsReviewed on 2/20/2026
Listen to what I had to say and explain things to me like I understood
- 5 out of 5 starsReviewed on 2/13/2026
Very good bedside manner
- 5 out of 5 starsReviewed on 2/13/2026
Dr. Gui and [staff] were both very thorough and compassionate during my initial consultation. They were excellent and took the time to listen and provided useful information. On a second visit for CT Simulation, both were very kind and supportive, as was the Tech ([staff]). All were essential in getting me through the process.
- 5 out of 5 starsReviewed on 1/21/2026
He was a very good provider
- 5 out of 5 starsReviewed on 1/9/2026
Dr. Gui was great. He really explained things to me and my wife which were very informative.
- 5 out of 5 starsReviewed on 1/5/2026
Dr. Gui was outstanding. He was thorough, very caring and kind, answered all questions and explained all treatment options. Couldn't have asked for a better doctor. I wish all doctors were like him.
- 5 out of 5 starsReviewed on 12/29/2025
Since I am new to radiation oncology, my visit with Dr. Gui was a wonderful, informative experience which left me confident in the next steps of my treatment. He also was understanding and kind enough to refer me to a radiation oncology facility closer to my home in central New Jersey. He also called me today (1/9/26) to see how my arrangements were coming along with MSK. It was a pleasure to meet him and work with him.
- 5 out of 5 starsReviewed on 12/12/2025
Dr Gui listened to my questions and fears. He provided honest answers and seemed to understand how anxious I was. He was firm when needed yet caring.
- 5 out of 5 starsReviewed on 11/17/2025
He is an excellent Doctor and is good the way he talk with me
- 5 out of 5 starsReviewed on 8/1/2025
Good bedside manner