Loading Complete
Charles J. Lowenstein

Charles J. Lowenstein, MD

Cardiology

Accepting New Patients
Online Booking

Highlights

Age Groups Seen

  • Young Adult 18-25
  • Adult 26-64
  • Older Adult 65+

Languages

  • English

Gender

Male

Johns Hopkins Affiliations:

  • Johns Hopkins School of Medicine Faculty

About Charles J. Lowenstein

Professional Titles

  • Michel Mirowski, M.D. Professor of Cardiology
  • Director, Division of Cardiology

Primary Academic Title

Professor of Medicine

Johns Hopkins Physician

Logo for Johns Hopkins Physician

Background

Charles Lowenstein, M.D., is a cardiologist in Baltimore, Maryland. He also serves as director of the Division of Cardiology and co-director of the Johns Hopkins Heart and Vascular Institute.

Dr. Lowenstein originally came to Johns Hopkins as a cardiology fellow in 1991 after completing his medical residency at Massachusetts General Hospital and a research fellowship at the Massachusetts Institute of Technology. In 1993, he joined the Johns Hopkins faculty and helped lead the Ciccarone Center for the Prevention of Heart Disease until he was recruited in 2009 to become the chief of cardiology and director of the Aab Cardiovascular Research Institute at the University of Rochester School of Medicine and Dentistry. In 2020 he was hired to lead the Division of Cardiology at Hopkins.

He has served on the NIH Atherosclerosis and Inflammation Cardiovascular Sciences study section, and is a member of the Sarnoff Cardiovascular Research Foundation, an organization that funds medical student research. Dr. Lowenstein’s research focuses on vascular biology, exploring molecular mechanisms of vascular inflammation and thrombosis.

Additional Academic Titles

Professor of Genetic Medicine

Research Interests

Vascular biology

Research Summary

Venous thromboembolism is a major cause of morbidity and mortality. Thrombosis can be caused by acquired or inherited factors, but the genetic contribution to thrombosis is not well defined. Genome wide association studies have recently uncovered new pathways that cause thrombotic disease in humans.

The Lowenstein Lab uses human genetics to discover and characterize novel genes that regulate thrombosis and hemostasis. We collaborate with genetic epidemiologists who perform GWAS to identify genetic variants linked to vascular inflammation or thrombosis. We then characterize genetic loci linked to vascular inflammation or thrombosis. These approaches have revealed new pathways in endothelial cells and platelets that contribute to thrombosis and may lead to novel therapies to prevent abnormal bleeding and thrombosis.

Current Projects:

  • Genetic causes of venous thromboembolism
  • Genetic causes of abnormal endothelial activation
  • Epigenetic regulation of coagulation factor production

Research Areas: vascular inflammation, thrombosis, hemostasis

Honors

  • Peter Dolphin Award, 1/1/05
  • Sir William Osler Young Investigator Award, 1/1/03
  • Young Investigators Conference on Atherosclerosis Award, 1/1/00

Memberships

  • NIH Atherosclerosis and Inflammation Cardiovascular Sciences study section
  • Sarnoff Cardiovascular Research Foundation
  • InterUrban Clinical Club
  • American Society for Clinical Investigation

Locations

  1. Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
    • 10755 Falls Road, Pavilion I STE 360, Lutherville, MD 21093
    • Get Directions

Expertise

Education

  • Fellowship: Johns Hopkins University School of Medicine, 1993
  • Fellowship: Massachusetts General Hospital, Medicine, 1991
  • Residency: Massachusetts General Hospital, Medicine, 1989
  • Medical Education: Harvard Medical School, MD, 1986

Board Certifications

  • Cardiovascular Disease: American Board of Internal Medicine, 2004
  • Internal Medicine: American Board of Internal Medicine, 1989

Insurance

Please contact the location directly to confirm your health plan is accepted.
Search plans
  • Aetna
  • CareFirst
  • Cigna
  • First Health
  • Geisinger Health Plan
  • HealthSmart/Accel
  • Johns Hopkins Health Plans
  • MultiPlan
  • Pennsylvania's Preferred Health Networks (PPHN)
  • Point Comfort Underwriters
  • Private Healthcare Systems (PHCS)
  • Veteran Affairs Community Care Network (Optum-VACCN)

Ratings & Reviews

4.8 out of 5

75 ratings, 24 reviews

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Overall Rating by Patient
Provider Listened Carefully
Provider Explained Things Clearly
Provider Knew Medical History
Provider Showed Respect
Provider Spent Enough Time
Search reviews
    5 out of 5 stars
    Reviewed on 3/3/2026

    He was very knowledgeable at courteous.

    5 out of 5 stars
    Reviewed on 2/17/2026

    He spent over an hour with me. I appreciated his straightforward approach. I feel confident of his diagnosis and treatment plan. I think he knows what he's talking about. That in itself is refreshing.

    5 out of 5 stars
    Reviewed on 2/3/2026

    He was very attentive, kind, and a good listener. He explained my condition in a way I could understand and he answered all my questions

    5 out of 5 stars
    Reviewed on 2/3/2026

    Dr Lowenstein is a cardiologist new to me, who will follow my cardiac health regularly.

    5 out of 5 stars
    Reviewed on 1/27/2026

    Dr. Lowenstein was well prepared for our visit. He's knowledgeable and friendly.

    5 out of 5 stars
    Reviewed on 1/6/2026

    Well prepared, very friendly, very professional

    4 out of 5 stars
    Reviewed on 12/30/2025

    Dr. Lowenstein spent the majority of the visit typing on the computer rather than interviewing me.

    5 out of 5 stars
    Reviewed on 12/16/2025

    Great.

    5 out of 5 stars
    Reviewed on 12/16/2025

    He is thorough and well prepared for appointments.

    5 out of 5 stars
    Reviewed on 12/9/2025

    Dr. Lowenstein has been my cardiologist for five years. He has my complete trust and respect.

    5 out of 5 stars
    Reviewed on 10/28/2025

    Dr. Lowenstein is incredibly informed and competent. He is also friendly and considerate.

    5 out of 5 stars
    Reviewed on 10/21/2025

    Ver knowledgeable. To the point but not rude.

    5 out of 5 stars
    Reviewed on 9/2/2025

    Thoroughly prepared.

    5 out of 5 stars
    Reviewed on 9/2/2025

    Wonderful provider.

    5 out of 5 stars
    Reviewed on 9/2/2025

    He is thorough, knowledgeable, and kind. He moves things along, but not at the expense of listening to his patients. He gives you confidence which makes working on health easier.

    5 out of 5 stars
    Reviewed on 8/26/2025

    The best possible

    5 out of 5 stars
    Reviewed on 7/22/2025

    The front desk lady was very professional and nice.

    5 out of 5 stars
    Reviewed on 7/8/2025

    Thorough, caring,addressed all of my health issues, showed concern for my wellbeing

    5 out of 5 stars
    Reviewed on 7/8/2025

    Very impressed with Dr. Lowenstein. Very informed and experienced -- made me feel that I was getting the best possible care. He asked questions and listened to my concerns.

    5 out of 5 stars
    Reviewed on 6/10/2025

    Excellent clinician. Thoughtful astute

    5 out of 5 stars
    Reviewed on 6/10/2025

    Very kind with amazing bedside manner.

    5 out of 5 stars
    Reviewed on 5/27/2025

    He was excellent

    5 out of 5 stars
    Reviewed on 5/20/2025

    Dr. Lowenstein was Incredibly thoughtful and clear In how he conducted the appointment.

    5 out of 5 stars
    Reviewed on 4/29/2025

    The doctor was and always very pleasant and friendly