
Highlights
Age Groups Seen
- Young Adult 18-25
- Adult 26-64
- Older Adult 65+
Languages
- English
In-Network Plans
View All Accepted Plans (12)Gender
MaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Charles J. Lowenstein
Professional Titles
- Michel Mirowski, M.D. Professor of Cardiology
- Director, Division of Cardiology
Primary Academic Title
Professor of Medicine
Johns Hopkins Physician
Background
Charles Lowenstein, M.D., is a cardiologist in Baltimore, Maryland. He also serves as director of the Division of Cardiology and co-director of the Johns Hopkins Heart and Vascular Institute.
Dr. Lowenstein originally came to Johns Hopkins as a cardiology fellow in 1991 after completing his medical residency at Massachusetts General Hospital and a research fellowship at the Massachusetts Institute of Technology. In 1993, he joined the Johns Hopkins faculty and helped lead the Ciccarone Center for the Prevention of Heart Disease until he was recruited in 2009 to become the chief of cardiology and director of the Aab Cardiovascular Research Institute at the University of Rochester School of Medicine and Dentistry. In 2020 he was hired to lead the Division of Cardiology at Hopkins.
He has served on the NIH Atherosclerosis and Inflammation Cardiovascular Sciences study section, and is a member of the Sarnoff Cardiovascular Research Foundation, an organization that funds medical student research. Dr. Lowenstein’s research focuses on vascular biology, exploring molecular mechanisms of vascular inflammation and thrombosis.
Videos
Additional Academic Titles
Professor of Genetic Medicine
Research Interests
Vascular biology
Research Summary
Venous thromboembolism is a major cause of morbidity and mortality. Thrombosis can be caused by acquired or inherited factors, but the genetic contribution to thrombosis is not well defined. Genome wide association studies have recently uncovered new pathways that cause thrombotic disease in humans.
The Lowenstein Lab uses human genetics to discover and characterize novel genes that regulate thrombosis and hemostasis. We collaborate with genetic epidemiologists who perform GWAS to identify genetic variants linked to vascular inflammation or thrombosis. We then characterize genetic loci linked to vascular inflammation or thrombosis. These approaches have revealed new pathways in endothelial cells and platelets that contribute to thrombosis and may lead to novel therapies to prevent abnormal bleeding and thrombosis.
Current Projects:
- Genetic causes of venous thromboembolism
- Genetic causes of abnormal endothelial activation
- Epigenetic regulation of coagulation factor production
Research Areas: vascular inflammation, thrombosis, hemostasis
Honors
- Peter Dolphin Award, 1/1/05
- Sir William Osler Young Investigator Award, 1/1/03
- Young Investigators Conference on Atherosclerosis Award, 1/1/00
Memberships
- NIH Atherosclerosis and Inflammation Cardiovascular Sciences study section
- Sarnoff Cardiovascular Research Foundation
- InterUrban Clinical Club
- American Society for Clinical Investigation
Locations
- Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
- 10755 Falls Road, Pavilion I STE 360, Lutherville, MD 21093
- Get Directions
- phone: 443-997-0270
- fax: 410-367-2448
Expertise
Education
- Fellowship: Johns Hopkins University School of Medicine, 1993
- Fellowship: Massachusetts General Hospital, Medicine, 1991
- Residency: Massachusetts General Hospital, Medicine, 1989
- Medical Education: Harvard Medical School, MD, 1986
Board Certifications
- Cardiovascular Disease: American Board of Internal Medicine, 2004
- Internal Medicine: American Board of Internal Medicine, 1989
Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- Veteran Affairs Community Care Network (Optum-VACCN)
Ratings & Reviews
4.8 out of 5
75 ratings, 23 reviewsThe Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
- 5 out of 5 starsReviewed on 2/17/2026
He spent over an hour with me. I appreciated his straightforward approach. I feel confident of his diagnosis and treatment plan. I think he knows what he's talking about. That in itself is refreshing.
- 5 out of 5 starsReviewed on 2/3/2026
Dr Lowenstein is a cardiologist new to me, who will follow my cardiac health regularly.
- 5 out of 5 starsReviewed on 2/3/2026
He was very attentive, kind, and a good listener. He explained my condition in a way I could understand and he answered all my questions
- 5 out of 5 starsReviewed on 1/27/2026
Dr. Lowenstein was well prepared for our visit. He's knowledgeable and friendly.
- 5 out of 5 starsReviewed on 1/6/2026
Well prepared, very friendly, very professional
- 4 out of 5 starsReviewed on 12/30/2025
Dr. Lowenstein spent the majority of the visit typing on the computer rather than interviewing me.
- 5 out of 5 starsReviewed on 12/16/2025
He is thorough and well prepared for appointments.
- 5 out of 5 starsReviewed on 12/16/2025
Great.
- 5 out of 5 starsReviewed on 12/9/2025
Dr. Lowenstein has been my cardiologist for five years. He has my complete trust and respect.
- 5 out of 5 starsReviewed on 10/28/2025
Dr. Lowenstein is incredibly informed and competent. He is also friendly and considerate.
- 5 out of 5 starsReviewed on 10/21/2025
Ver knowledgeable. To the point but not rude.
- 5 out of 5 starsReviewed on 9/2/2025
He is thorough, knowledgeable, and kind. He moves things along, but not at the expense of listening to his patients. He gives you confidence which makes working on health easier.
- 5 out of 5 starsReviewed on 9/2/2025
Wonderful provider.
- 5 out of 5 starsReviewed on 9/2/2025
Thoroughly prepared.
- 5 out of 5 starsReviewed on 8/26/2025
The best possible
- 5 out of 5 starsReviewed on 7/22/2025
The front desk lady was very professional and nice.
- 5 out of 5 starsReviewed on 7/8/2025
Thorough, caring,addressed all of my health issues, showed concern for my wellbeing
- 5 out of 5 starsReviewed on 7/8/2025
Very impressed with Dr. Lowenstein. Very informed and experienced -- made me feel that I was getting the best possible care. He asked questions and listened to my concerns.
- 5 out of 5 starsReviewed on 6/10/2025
Very kind with amazing bedside manner.
- 5 out of 5 starsReviewed on 6/10/2025
Excellent clinician. Thoughtful astute
- 5 out of 5 starsReviewed on 5/27/2025
He was excellent
- 5 out of 5 starsReviewed on 5/20/2025
Dr. Lowenstein was Incredibly thoughtful and clear In how he conducted the appointment.
- 5 out of 5 starsReviewed on 4/29/2025
The doctor was and always very pleasant and friendly