Bipasha Mukherjee-Clavin, MD, PhD

• Co-director of the Johns Hopkins Charcot-Marie-Tooth Disease Clinic

Dr. Bipasha Mukherjee-Clavin is an Assistant Professor of Neurology in the Johns Hopkins University School of Medicine.  She cares for patients with neuromuscular disorders, with a special focus on patients with peripheral neuropathy, immune-mediated neuropathy, and inherited neuropathy (also known as Charcot-Marie-Tooth disease).  She sees patients in the Johns Hopkins Peripheral Nerve and multidisciplinary Charcot-Marie-Tooth clinics, and performs electromyography in the Johns Hopkins EMG lab.

As a stem cell biology-trained scientist, Dr. Mukherjee-Clavin's research is focused on the use of patient-derived induced pluripotent stem cells to model genetic Schwann cell and peripheral nerve disorders to undercover novel pathways and potential treatments.  During her PhD she published one of the first studies of CMT1A using patient derived stem cells (Comparison of three congruent patient-specific cells types for the modelling of a human genetic Schwann-cell disorder. Nature Biomedical Engineering. volume 3, pages 571–582 (2019)).  In 2022, she was awarded the Passano award, given to a promising early career physician-scientist in the Johns Hopkins University School of Medicine.

Dr. Mukherjee-Clavin completed her undergraduate studies at the University of California, Berkeley.  She then completed her MD/PhD degrees, Neurology residency, and clinical Neuromuscular fellowship in the Johns Hopkins University School of Medicine.  She joined the Johns Hopkins Neurology faculty in 2022.

• Charcot-Marie Tooth Center
• Peripheral Nerve Center

Inherited Neuropathies Consortium

INCbase

IMAGiNe

TRPV4 natural history study

• Mukherjee-Clavin B, Mi R, Kern B, Choi IY, Lim H, Oh Y, Lannon B, Kim KJ, Bell S, Hur JK, Hwang W, Che YH, Habib O, Baloh RH, Eggan K, Brandacher G, Hoke A, Studer L, Kim YJ, Lee G. Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder. Nature Biomedical Engineering. 2019 Jul;3(7):571-582

• Mukherjee-Clavin B, Tomishima M, Lee G.  Current approaches for efficient genetic editing in human pluripotent stem cells. Frontiers in Biology.  2013 Oct; 8(5): 461-467

• Lee G, Ramirez CN, Kim H, Zeltner N, Liu B, Radu C, Bhinder B, Kim YJ, Choi IY, Mukherjee-Clavin B, Djaballah H, Studer L.  Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression. Nature Biotechnology.  2012 Dec; 30(12):1244-8

• Merkin Peripheral Neuropathy and Nerve Regeneration Center Research Scholar, Merkin Peripheral Neuropathy and Nerve Regeneration Center, 8/1/22
• Passano Physician Scientist Award, Passano Foundation, 7/1/22
• American Academy of Neurology Clinical Research Training Scholarship, American Academy of Neurology, 7/1/22
• Jay Slotkin Award for excellence in neurological research during neurology residency, Johns Hopkins Neurology, 6/1/21
• NIH NINDS R25 Award, NIH, 7/1/20

• American Academy of Neurology
• American Neurological Association
• International Society for Stem Cell Research
• Peripheral Nerve Society junior committee member