Highlights
Age Groups Seen
- Young Adult 18-25
- Adult 26-64
- Older Adult 65+
Languages
- French
- Portuguese
- Spanish
- English
In-Network Plans
View All Accepted Plans (12)Gender
MaleJohns Hopkins Affiliations:
- Johns Hopkins School of Medicine Faculty
About Antonio Carlos Wolff
Professional Titles
- Co-Director, Breast & Gynecologic Cancer Program
- Co-Director, Women's Wellness & Healthy Aging Program
Primary Academic Title
Professor of Oncology
Johns Hopkins Physician
Background
Dr. Antonio Wolff is internationally recognized for his work on breast cancer biomarkers, including HER2. As a practicing oncologist and clinical translational researcher, his research has been pivotal to improve the quality of breast cancer biomarker testing in breast cancer, including HER2 and estrogen receptor testing. Among his leadership accomplishments is ensuring that sophisticated laboratory findings are translated into improved clinical care in breast cancer. He is a Fellow of the American Society of Clinical Oncology (ASCO), a Komen Scholar and a Breast Cancer Research Foundation investigator. He has served as associate editor for Journal of Clinical Oncology, and serves on the National Comprehensive Cancer Network (NCCN) Guideline Steering Committee. He is a leader of the Translational Breast Cancer Research Consortium (TBCRC), and one of the principal investigators of the Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies (EVOLVE) in Metastatic Breast Cancer, which was one of the three disease groups recently awarded by ARPA-H to conduct innovative trials using Advanced Analysis for Precision Cancer Therapy (ADAPT). After many years of service as Breast Committee Chair in the ECOG-ACRIN Clinical Trial Network of the National Cancer Institute (NCI), he was elected in 2024 as Co-Chair of the NCI Breast Cancer Steering Committee and appointed to the international steering committee of the Oxford Overview Collaborative, which are positions aimed at advancing clinical trials in breast cancer. At Johns Hopkins, he is an elected member of the Miller Coulson Academy of Clinical Excellence and was honored during the 125th Anniversary Living the Hopkins Mission celebrations of the JHU School of Medicine.
Centers and Institutes
X Profile
Clinical Trial Keywords
breast cancer, biomarkers, survivorship
Find a Clinical Trial
View all trials by this principal investigator.
Videos
Recent News Articles and Media Coverage
Why Clinical Trials? Because they matter, X (October 12, 2022)
Additional Academic Titles
Professor of Pathology
Research Interests
Breast Cancer, Cancer Biomarkers, Clinical Trials, Cancer Survivorship
Google Scholar - Publications
https://scholar.google.com/citations?hl=en&user=UR2BQW8AAAAJ
Selected Publications
Wolff AC, Blackford AL, Visvanathan K, Rugo HS, Moy B, Goldstein LJ, Stockerl-Goldstein K, Neumayer L, Langbaum TS, Theriault RL, Hughes ME, Weeks JC, Karp JE. Risk of marrow neoplasms after adjuvant breast cancer therapy: the national comprehensive cancer network experience. J Clin Oncol. 2015 Feb 1;33(4):340-8. doi: 10.1200/JCO.2013.54.6119. Epub 2014 Dec 22. PMID: 25534386
Wolff AC, Somerfield MR, Dowsett M, Hammond MEH, Hayes DF, McShane LM, Saphner TJ, Spears PA, Allison KH. Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: ASCO-College of American Pathologists Guideline Update. J Clin Oncol. 2023 Jun 7:JCO2202864. doi: 10.1200/JCO.22.02864. Online ahead of print. PMID: 37284804
Kim HS, Umbricht CB, Illei PB, Cimino-Mathews A, Cho S, Chowdhury N, Figueroa-Magalhaes MC, Pesce C, Jeter SC, Mylander C, Rosman M, Tafra L, Turner BM, Hicks DG, Jensen TA, Miller DV, Armstrong DK, Connolly RM, Fetting JH, Miller RS, Park BH, Stearns V, Visvanathan K, Wolff AC, Cope L. Optimizing the Use of Gene Expression Profiling in Early-Stage Breast Cancer. J Clin Oncol. 2016 Dec 20;34(36):4390-4397. doi: 10.1200/JCO.2016.67.7195. Epub 2016 Oct 31. PMID: 27998227
Santa-Maria CA, Wolff AC. Antibody-Drug Conjugates in Breast Cancer: Searching for Magic Bullets. J Clin Oncol. 2023 Feb 1;41(4):732-735. doi: 10.1200/JCO.22.02217. Epub 2022 Nov 29. PMID: 36446052
Visvanathan K, Cope L, Fackler MJ, Considine M, Sokoll L, Carey LA, Forero-Torres A, Ingle JN, Lin NU, Nanda R, Storniolo AM, Tulac S, Venkatesan N, Wu NC, Marla S, Campbell S, Bates M, Umbricht CB, Wolff AC, Sukumar S. Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial. Clin Cancer Res. 2023 Feb 16;29(4):784-790. doi: 10.1158/1078-0432.CCR-22-2128. PMID: 36534524
Honors
- Scholar, Susan G Komen Foundation, 4/1/23
- Member, JHU Miller Coulson Academy of Clinical Excellence, 4/1/18
- Recipient, NCI Cancer Clinical Investigator Team Leadership Award, 7/1/10
- Fellow, American Society of Clinical Oncology, 6/1/10
- Fellow, American College of Physicians, 7/1/04
Memberships
- American Society of Clinical Oncology
- European Society of Medical Oncology
Professional Activities
- ECOG-ACRIN Breast Cancer Committee, Chair, 1/1/18
- The Journal of Clinical Oncology, Associate Editor for Breast Cancer, 1/1/12 - 6/30/22
Locations
- Johns Hopkins Health Care & Surgery Center - Green Spring Station, Lutherville
- 10803 Falls Road, Pavilion III STE 1500, Lutherville, MD 21093
- Get Directions
- phone: 410-583-2970
- fax: 410-583-2980
- Skip Viragh Outpatient Cancer Center
- 201 North Broadway Street, Viragh BLDG 10th FL, Baltimore, MD 21287
- Get Directions
- phone: 410-955-8964
- fax: 410-367-2194
Expertise
Education
- Fellowship: Johns Hopkins University School of Medicine, Medical Oncology, 1995
- Fellowship: Barnes-Jewish Health, Hematology and Oncology, 1992
- Residency: The Mount Sinai Hospital, Internal Medicine, 1991
- Residency: MedStar Good Samaritan Hospital, Internal Medicine, 1990
- Medical Education: Universidade Federal do Rio de Janeiro, MD, 1986
Board Certifications
- Medical Oncology: American Board of Internal Medicine, 1995
Insurance
- Aetna
- CareFirst
- Cigna
- First Health
- Geisinger Health Plan
- HealthSmart/Accel
- Johns Hopkins Health Plans
- MultiPlan
- Pennsylvania's Preferred Health Networks (PPHN)
- Point Comfort Underwriters
- Private Healthcare Systems (PHCS)
- Veteran Affairs Community Care Network (Optum-VACCN)
Ratings & Reviews
4.8 out of 5
98 ratings, 37 reviewsThe Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
- 5 out of 5 starsReviewed on 3/19/2026
He is one of best doctors I have seen in a long time. He was very easy to talk to. He was very detailed. He provided me with all the test I needed to start my treatmentplan. I am very pleased with him.
- 5 out of 5 starsReviewed on 3/4/2026
Dr. Wolff is wonderful! He listens intently on what I'm saying about my issue and makes me feel like I'm a part of this process on my care. He always explains things in a way that makes sure I understand and he makes me feel comfortable to speak up about my health.
- 1 out of 5 starsReviewed on 3/4/2026
I have been a patient of Dr Antonio Wolff's since 2014. I see him every year and every year he is Never on time. I always have to wait over 40 minutes or more.
- 5 out of 5 starsReviewed on 2/19/2026
Dr Wolff is the most caring and concerned physician that I have ever had. He is wonderful.
- 5 out of 5 starsReviewed on 2/12/2026
He was very friendly and helpful.
- 5 out of 5 starsReviewed on 2/11/2026
I feel very fortunate to have been under Dr Wolff's care. He has been kind, and grounded, and a companion for me during my cancer journey. I trust him. We have intelligent conversations about the most recent findings in the field as they pertain to my situation. I feel seen. Thank you!
- 5 out of 5 starsReviewed on 1/29/2026
I'm very grateful for the time, attention, and expertise everyone on the oncology team provided.
- 5 out of 5 starsReviewed on 12/23/2025
Every doctor should be as good as Dr. Wolff!!
- 5 out of 5 starsReviewed on 12/23/2025
In a lifetime of or having had Medical care, I have never had a more caring physician or physician assistant care then I had with Dr Wolff and assistant [staff]. They are over the top! His team are all very caring and patient with a person as I that's going through cancer.
- 5 out of 5 starsReviewed on 12/17/2025
Excellent in all respects
- 5 out of 5 starsReviewed on 12/17/2025
Dr. Wolff is an exceptional oncologist.
- 5 out of 5 starsReviewed on 12/16/2025
Very knowledgeable and helpful provider
- 5 out of 5 starsReviewed on 11/13/2025
Dr Wolff is a compassionate, knowledgeable provider who takes his time with you and listens to you.
- 5 out of 5 starsReviewed on 11/12/2025
Excellent oncologist. Very happy with Him.
- 5 out of 5 starsReviewed on 10/28/2025
I felt positive after meeting with Dr. Wolff. The conversation was calm and pleasant- no stress. Dr Wolff provided and discussed my treatment plan. I felt confident.
- 5 out of 5 starsReviewed on 10/23/2025
A very good experience with Dr Wolff- and all ppl involved-- highly satisfied
- 5 out of 5 starsReviewed on 10/21/2025
Excellent consultation for stage IV cancer. Dr. Wolff listened carefully and asked questions appropriately.
- 5 out of 5 starsReviewed on 10/16/2025
Dr. Wolff, whom I met for the first time at this visit, was incredibly knowledgeable, experienced, and kind. He explained my situation with great clarity, was a great listener, and absolutely did not rush through this appointment.
- 5 out of 5 starsReviewed on 10/2/2025
Kind, very knowledgable, relatable, listens, understands
- 4 out of 5 starsReviewed on 9/11/2025
Always late
- 3 out of 5 starsReviewed on 9/11/2025
He has never been on time or even close for any visit
- 5 out of 5 starsReviewed on 9/4/2025
Dr Wolfe is great.
- 5 out of 5 starsReviewed on 8/28/2025
Very comfortable with Dr Wolff
- 5 out of 5 starsReviewed on 8/28/2025
Dr. Wolff always gives me plenty of time and never makes me feel rushed. He reviews my results with me and makes sure I understand all of his decisions. He has a terrific bedside manner and makes me feel very much at ease.
- 5 out of 5 starsReviewed on 8/12/2025
Very good.
- 5 out of 5 starsReviewed on 8/7/2025
ACW helped save my life and is an amazing oncologist.
- 5 out of 5 starsReviewed on 7/29/2025
Easy to talk. Listen carefully to my concerns.
- 4 out of 5 starsReviewed on 6/26/2025
He makes sure I get the best tests and follow up needed.
- 5 out of 5 starsReviewed on 6/26/2025
Dr Wolff has been my doctor for many years. I always feel comfortable with him. He is an OUTSTANDING doctor! He explains everything, listens to your concerns and is personable.
- 5 out of 5 starsReviewed on 6/12/2025
Very respectful and caring
- 4 out of 5 starsReviewed on 5/27/2025
The provider was warm, courteous, competent and engaged. I appreciated that he did not rush through the visit, he took time to respond to my comments and questions. I also appreciated that he was considerate of my specific medical history in regard to recommendations for my care/treatment going forward rather than just sticking to the typical protocol/standards of care based on my cancer diagnosis and treatment thus far
- 5 out of 5 starsReviewed on 5/27/2025
Dr Wolff took time to discuss and explain clearly the medical issues related to my disease. He was caring and answered all questions I had.
- 5 out of 5 starsReviewed on 5/22/2025
Repeat visits. Always positive & informative a
- 5 out of 5 starsReviewed on 5/22/2025
I see Dr. Wolff only for breast cancer related issues. He is always thorough, respectful, and pleasant. He also ensures that I know what he is doing/thinking, and coordinates well with others of my cancer team.
- 5 out of 5 starsReviewed on 5/22/2025
Provider listened well, was not rushed, explained everything in a very communicable manner.
- 4 out of 5 starsReviewed on 5/15/2025
Dr Wolff is knowledgeable and offers good information and advice. But I always have to wait at least an hour, sometimes two! My time is valuable also.
- 5 out of 5 starsReviewed on 4/23/2025
Dr Wolff is excellent. He is easy to talk to, and he listens. He works ""with"" the patient.