Ana-Maria Orbai, MD, MHS

Professional Titles

• Director, Psoriatic Arthritis Program

Primary Academic Title

Associate Professor of Medicine

Background

Centers and Institutes

Arthritis Center

Find a Clinical Trial

Recent News Articles and Media Coverage

• Arthritis Makes Life With Chronic Diseases Worse, U.S. News & World Report, Aug. 6, 2015

  What Are Common Symptoms of Autoimmune Disease?, Johns Hopkins Medicine

  Autoimmune Disease: Why Is My Immune System Attacking Itself? Johns Hopkins Medicine

  Psoriatic Arthritis – Disease Overview, Johns Hopkins Medicine, Johns Hopkins Rheumatology (May 7, 2018)

  Diagnosing Psoriatic Arthritis, Johns Hopkins Rheumatology (May 9, 2018)

  Treating Psoriatic Arthritis, Johns Hopkins Rhematology (May 10, 2018)

Lab Website

Ana-Marie Orbai Lab - Lab Website

• The Ana-Marie Orbai Lab focuses on inflammatory arthritis. Current clinical research projects in the lab examine patient symptoms and experiences in rheumatic diseases and inflammatory arthritis. We focus on stiffness in rheumatoid arthritis and patient-reported outcomes. Previous research in the lab focused on systemic lupus erythemaous (SLE).

Research Summary

Dr. Orbai directs the Psoriatic Arthritis Program in the Johns Hopkins Arthritis Center. Her research focus is characterization of psoriatic disease phenotypes and individualizing treatment strategies. The goal is to improve long-term patient outcomes in psoriatic arthritis.Dr. Orbai co-chaired the international GRAPPA-OMERACT Psoriatic Arthritis working group through their update of the PsA core outcome set for clinical trials in 2016.  She subsequently led the endorsement of the first core patient reported outcome measure for psoriatic arthritis clinical trials in 2018. Dr. Orbai has been an expert panel member for treatment recommendations for psoriatic arthritis. Dr. Orbai serves on the steering committee of Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) and on the Board of Medical Directors for the National Psoriasis Foundation.  She is a reviewer for many rheumatology journals.

Dr. Orbai contributed to the development of the 2012 Systemic Lupus International Collaborating Clinics (SLICC) classification criteria for systemic lupus erythematosus with Dr. Michelle Petri in the Johns Hopkins Lupus Center.

PubMed - Publications

http://www.ncbi.nlm.nih.gov/pubmed/?term=orbai+am

Selected Publications

• Orbai AM, de Wit M, Mease P, Shea JA, Gossec L, Leung YY, Tillett W, Elmamoun M, Callis Duffin K, Campbell W, Christensen R, Coates L, Dures E, Eder L, FitzGerald O, Gladman D, Goel N, Grieb SD, Hewlett S, Hoejgaard P, Kalyoncu U, Lindsay C, McHugh N, Shea B, Steinkoenig I, Strand V, Ogdie A. International patient and physician consensus on a psoriatic arthritis core outcome set for clinical trials.Ann Rheum Dis. 2017 Apr;76(4):673-680. doi: 10.1136/annrheumdis-2016-210242. Epub 2016 Sep 9. PMID: 27613807

• Orbai AM, Holland R, Leung YY, Tillett W, Goel N, Christensen R, McHugh N, Gossec L, de Wit M, Højgaard P, Coates LC, Mease PJ, Birt J, Fallon L, FitzGerald O, Ogdie A, Shea B, Strand V, Callis Duffin K, Tugwell P, Beaton D, Gladman DD. PsAID12 Provisionally Endorsed at OMERACT 2018 as Core Outcome Measure to Assess Psoriatic Arthritis-specific Health-related Quality of Life in Clinical Trials. J Rheumatol. 2018 Dec 15. pii: jrheum.181077. doi: 10.3899/jrheum.181077. [Epub ahead of print] PMID: 30554154

• Gorlier C, Orbai AM, Puyraimond-Zemmour D, Coates LC, Kiltz U, Leung YY, Palominos P, Cañete JD, Scrivo R, Balanescu A, Dernis E, Tälli S, Ruyssen-Witrand A, Soubrier M, Aydin SZ, Eder L, Gaydukova I, Lubrano E, Kalyoncu U, Richette P, Husni ME, de Wit M, Smolen JS, Gossec L. Comparing patient-perceived and physician-perceived remission and low disease activity in psoriatic arthritis: an analysis of 410 patients from 14 countries. Ann Rheum Dis. 2018 Nov 15. pii: annrheumdis-2018-214140. doi: 10.1136/annrheumdis-2018-214140. [Epub ahead of print] PMID: 30442648

• Petri M, Orbai AM, Alarcón GS, Gordon C, Merrill JT, Fortin PR, Bruce IN, Isenberg D, Wallace DJ, Nived O, Sturfelt G, Ramsey-Goldman R, Bae SC, Hanly JG, Sánchez-Guerrero J, Clarke A, Aranow C, Manzi S, Urowitz M, Gladman D, Kalunian K, Costner M, Werth VP, Zoma A, Bernatsky S, Ruiz-Irastorza G, Khamashta MA, Jacobsen S, Buyon JP, Maddison P, Dooley MA, van Vollenhoven RF, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim SS, Fessler BJ, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG Jr, Sigler L, Hameed S, Fang H, Pham N, Brey R, Weisman MH, McGwin G Jr, Magder LS. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum. 2012 Aug;64(8):2677-86. doi: 10.1002/art.34473. PMID: 22553077

• Singh JA, Guyatt G, Ogdie A, Gladman DD, Deal C, Deodhar A, Dubreuil M, Dunham J, Husni ME, Kenny S, Kwan-Morley J, Lin J, Marchetta P, Mease PJ, Merola JF, Miner J, Ritchlin CT, Siaton B, Smith BJ, Van Voorhees AS, Jonsson AH, Shah AA, Sullivan N, Turgunbaev M, Coates LC, Gottlieb A, Magrey M, Nowell WB, Orbai AM, Reddy SM, Scher JU, Siegel E, Siegel M, Walsh JA, Turner AS, Reston J. Special Article: 2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis. Arthritis Rheumatol. 2019 Jan;71(1):5-32. doi: 10.1002/art.40726. Epub 2018 Nov 30. PMID: 30499246

Honors

• Jerome L Greene Foundation Scholar, Jerome L Greene Foundation, 4/1/18
• Scientist Development Award, Rheumatology Research Foundation, 7/1/14

Memberships

• American College of Rheumatology,

  Member

• Maryland Society for the Rheumatic Diseases,

  Member

• Group for Research and Assessment of Psoriasis and Psoriatic Arthritis