Sarbjit S. Saini, MD

Professional Titles

• Program Director

Primary Academic Title

Professor of Medicine

Background

Centers and Institutes

Asthma and Allergy Center

Clinical Trial Keywords

IgE, urticaria

Clinical Trials Summary

Urticaria

Angioedema

Allergic Rhinitis

Find a Clinical Trial

Contact for Research Inquiries

5501 Hopkins Bayview Circle
Room 2B.71B
Baltimore, MD 21224

Research Interests

Basophil and mast cell biology, IgE mediated diseases, IgE receptor activation

Lab Website

Sarbjit Saini Lab

• The research in the Sarbjit Saini Laboratory focuses on IgE receptor biology and IgE receptor-mediated activation of blood basophils and mast cells. We have examined the role of IgE receptor expression and activation in allergic airways disease, anaphylaxis and chronic urticaria. Our research has been supported by the NIH, American Lung Association and the AAAAI. Our current research interests have focused mechanisms of diease in allergic asthma, allergic rhinitis and also translational studies in chronic idiopathic urticaria.

Research Summary

My research has focused on the IgE receptor activation of human basophils and mast cells. My early work focused on the mechanisms of IgE receptor regulation and I have led several translational studies in allergic subjects to better understand the role of allergen specific IgE. My recent studies focus on the mechanisms underlying chronic urticaria, where we found altered IgE-receptor signaling related to the phenotype of mast cells and basophils. 

Memberships

• AAAAI-Fellow 2002
• ACAAI
• AAFA-Board
• ABAI
• AAAAI- Board

Professional Activities

Allergy and Clinical Immunology Fellowship, Program Director, 9/1/08