Fredrick Wigley, MD

5.0155 ratings, 77 reviews

Rheumatology

Accepting New Patients

Highlights

Age Groups Seen

Young Adult 18-25
Adult 26-64
Older Adult 65+

Languages

English

In-Network Plans

View All Accepted Plans (12)

Gender

Male

Johns Hopkins Affiliations:

Johns Hopkins School of Medicine Faculty

About Fredrick Wigley

Professional Titles

Director, The Johns Hopkins Scleroderma Center
Martha McCrory Professor of Medicine

Primary Academic Title

Professor of Medicine

Johns Hopkins Physician

Background

Dr. Wigley received his M.D. degree from the University of Florida College of Medicine. He completed an internship and residency at Johns Hopkins where he also trained in a postdoctoral fellowship program. Dr. Wigley is a physician-scientist whose specialty is Raynaud’s phenomenon and scleroderma. He founded The Johns Hopkins Scleroderma Center with Robert A. Wise, M.D., of the Johns Hopkins Division of Pulmonary Medicine. Dr. Wigley has been honored with two American College of Rheumatology awards over the past couple years. He received the ACR Distinguished Clinician Scholar Award in 2009 and the ACR Masters Award in 2011.

Centers and Institutes

Scleroderma Center

Clinical Trial Keywords

Raynaud's phenomenon; Scleroderma

Lab Website

Fredrick Wigley Lab

The Frederick Wigley Lab is interested in the signs, symptoms and causes of scleroderma. We are testing new treatments for Raynaud√ïs phenomenon and scleroderma. Understanding the treatment approach to Raynaud's phenomenon and associated ischemia and how to prevent digital ulcers is important for clinicians caring for these patients. Work in our lab has provided guidance in the management of Raynaud's phenomenon and digital ischemic ulcers, including options for the practical pharmacologic and nonpharmacologic interventions.

Research Summary

Dr. Wigley’s research focuses on the events that cause scleroderma and on the signs and symptoms of scleroderma. He is testing new treatments for Raynaud’s phenomenon and scleroderma.

PubMed - Publications

http://www.ncbi.nlm.nih.gov/pubmed/?term=Wigley+FM%5BAuthor%5D

Selected Publications

1. Joseph CG, Darrah E, Shah AA, Skora AD, Casciola-Rosen LA, Wigley FM, Boin F, Fava A, Thoburn C, Kinde I, Jiao Y, Papadopoulos N, Kinzler KW, Vogelstein B, Rosen A. Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer. Science. 2013 Dec 5. [Epub ahead of print] PMID: 24310608
2. McMahan ZH, Wigley FM. Novel investigational agents for the treatment of scleroderma. Expert Opin Investig Drugs. 2013 Nov 22. [Epub ahead of print] PMID: 24261610
3. Gerber EE, Gallo EM, Fontana SC, Davis EC, Wigley FM, Huso DL, Dietz HC. Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma. Nature. 2013 Nov 7;503(7474):126-30. doi: 10.1038/nature12614. Epub 2013 Oct 9. PMID: 24107997
4. Tedford RJ, Mudd JO, Girgis RE, Mathai SC, Zaiman AL, Housten-Harris T, Boyce D, Kelemen BW, Bacher AC, Shah AA, Hummers LK, Wigley FM, Russell SD, Saggar R, Saggar R, Maughan WL, Hassoun PM, Kass DA. Right ventricular dysfunction in systemic sclerosis-associated pulmonary arterial hypertension. Circ Heart Fail. 2013 Sep 1;6(5):953-63. PMID: 23797369
5. Gelber AC, Manno RL, Shah AA, Woods A, Le EN, Boin F, Hummers LK, Wigley FM. Race and association with disease manifestations and mortality in scleroderma: a 20-year experience at the Johns Hopkins Scleroderma Center and review of the literature. Medicine (Baltimore). 2013 Jul;92(4):191-205. doi: 10.1097/MD.0b013e31829be125. Review. PMID: 23793108
6. Matucci-Cerinic M, Kahaleh B, Wigley FM. Review: evidence that systemic sclerosis is a vascular disease. Arthritis Rheum. 2013 Aug;65(8):1953-62. doi: 10.1002/art.37988. Review. No abstract available. PMID: 23666787
7. Cottrell TR, Wise RA, Wigley FM, Boin F. The degree of skin involvement identifies distinct lung disease outcomes and survival in systemic sclerosis. Ann Rheum Dis. 2013 Apr 20. [Epub ahead of print] PMID: 23606705
8. Shah AA, Wigley FM. My approach to the treatment of scleroderma. Mayo Clin Proc. 2013 Apr;88(4):377-93. doi: 10.1016/j.mayocp.2013.01.018. Review. PMID: 23541012
9. Hummers LK, Dugowson CE, Dechow FJ, Wise RA, Gregory J, Michalek J, Yenokyan G, McGready J, Wigley FM. A multi-centre, blinded, randomised, placebo-controlled, laboratory-based study of MQX-503, a novel topical gel formulation of nitroglycerine, in patients with Raynaud phenomenon. Ann Rheum Dis. 2013 Dec 1;72(12):1962-7. doi: 10.1136/annrheumdis-2012-201536. Epub 2012 Dec 25. PMID: 23268365
10. Shah AA, Chung SE, Wigley FM, Wise RA, Hummers LK. Changes in estimated right ventricular systolic pressure predict mortality and pulmonary hypertension in a cohort of scleroderma patients. Ann Rheum Dis. 2013 Jul;72(7):1136-40. doi: 10.1136/annrheumdis-2012-201861. Epub 2012 Aug 11. PMID: 22887850

Locations

Johns Hopkins Bayview Medical Center
- 5501 Hopkins Bayview Circle, Floor 1, Baltimore, MD 21224
- Get Directions
- phone: 443-997-1552
- fax: 410-550-1033

Expertise

Education

Fellowship: Johns Hopkins University School of Medicine, Rheumatology, 1979
Residency: Johns Hopkins University School of Medicine, Medicine, 1975
Medical Education: University of Florida College of Medicine, Medicine, MD, 1972

Board Certifications

Rheumatology: American Board of Internal Medicine, 1980
Internal Medicine: American Board of Internal Medicine, 1975

Insurance

Please contact the location directly to confirm your health plan is accepted.

Search plans

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Aetna
CareFirst
Cigna
First Health
Geisinger Health Plan
HealthSmart/Accel

Johns Hopkins Health Plans
MultiPlan
Pennsylvania's Preferred Health Networks (PPHN)
Point Comfort Underwriters
Private Healthcare Systems (PHCS)
Veteran Affairs Community Care Network (Optum-VACCN)

Ratings & Reviews

5 out of 5

155 ratings, 77 reviews

The Patient Rating score is an average of all responses to physician related questions on the national CG-CAHPS Medical Practice patient experience survey through Press Ganey. Responses are measured on a scale of 1 to 5, with 5 being the best score. Comments are also gathered from our CG-CAHPS Medical Practice Survey through Press Ganey and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.

Overall Rating by Patient

Provider Listened Carefully

Provider Explained Things Clearly

Provider Knew Medical History

Provider Showed Respect

Provider Spent Enough Time

Search reviews

Search Reviews

5 out of 5 stars
Reviewed on 4/15/2026
Dr. Wigley, 20 years he is truly the best physician I have ever had any contact with. If I'm sick at home. Because and check on me to make sure I'm doing good. He checks on me when I'm in his office. He's patient kind understanding, respectful, and very patient. He is the best.
5 out of 5 stars
Reviewed on 4/14/2026
Dr. Wigley saved my life.
5 out of 5 stars
Reviewed on 4/8/2026
Dr. Fredrick Wigley has been an extraordinary presence in my life during a very difficult time. From our very first meeting, I felt that I was in the hands of someone who truly understands not only the complexity of my condition but also the emotional weight that comes with it.He listens carefully, explains everything with clarity, and approaches each step with calm confidence. His expertise gives me trust, but his kindness gives me strength. I am deeply grateful for his care and feel very fortunate to be his patient.
5 out of 5 stars
Reviewed on 4/7/2026
I come from Florida to see Dr. Wigley because he listens and is so thorough on his exams
5 out of 5 stars
Reviewed on 4/7/2026
Dr. Wigley is terrific. I really appreciate his knowledge, expertise and attention to detail. He listens carefully and summarizes everything at the end of the meeting
5 out of 5 stars
Reviewed on 4/1/2026
Excellent
5 out of 5 stars
Reviewed on 3/31/2026
I have been a patient of Dr. Wigley for over 20 years. I have to travel some distance to attend an office visit with him. He is very thorough in his questioning and physical examination. The same for his explanations. He definitely listens to me. He also explains the bases for any future testing that he orderse.
5 out of 5 stars
Reviewed on 3/24/2026
He is the best!
5 out of 5 stars
Reviewed on 3/18/2026
Dr Wigley is a wonderful doctor. He is a gem and feel I have the best care
5 out of 5 stars
Reviewed on 3/18/2026
Dr. Wigley is the best!
5 out of 5 stars
Reviewed on 3/17/2026
Dr. Wigley is an excellent caring physician. Who truly wants to help his patients and goes to great lengths to understand and address my issues and concerns Best Doctor I ever had. Thank God for such a caring person and physician.
5 out of 5 stars
Reviewed on 3/17/2026
Dr. Wigley is among the best of the best. He's just a great doctor. I'm so glad he's my doctor.
5 out of 5 stars
Reviewed on 3/17/2026
Best doc on the planet
5 out of 5 stars
Reviewed on 3/11/2026
He was very knowledgeable and informative
5 out of 5 stars
Reviewed on 3/10/2026
Exceptional
5 out of 5 stars
Reviewed on 3/10/2026
Dr Wigley has been my Rheumatologist for 40 years. He is exceptional in every way. He is is thorough, kind, caring and the provider that I trust 1,000 percent. He educates me, answers questions and is always there when needed. If other providers were the provider that Dr Wigley is patients would receive the very best care possible. I compare other physicians to Dr Wigley and there is no comparison.
5 out of 5 stars
Reviewed on 3/3/2026
Dr Wigley is my doctor for the last 13 years. He is knowledgeable about not just Scleroderma but impact it has on many organs. He keeps my condition stable
5 out of 5 stars
Reviewed on 2/25/2026
Very good.
5 out of 5 stars
Reviewed on 2/25/2026
Excellent provider. Dr Wigley always is prepared and knows my case. He is informative and professional. He is my favorite doctor of all the doctors I see.
5 out of 5 stars
Reviewed on 2/24/2026
Dr. Wigley excels in all aspects of medical and patient care.. He is a gift!
5 out of 5 stars
Reviewed on 2/17/2026
Extremely knowledgeable and has the ability to explain in laymen's terms. He is professional and personable and shows concern and compassion.
5 out of 5 stars
Reviewed on 2/17/2026
Dr wigley is a very knowledgeable compassionate excellent dr
5 out of 5 stars
Reviewed on 2/10/2026
This Doctor is a phenomenal physician who is extremely knowledgeable in his profession that takes time to listen and care for his patients.
5 out of 5 stars
Reviewed on 2/4/2026
Dr. Wigley is someone whom every medical professional should emulate: Knowledgeble, thorough, and caring.
5 out of 5 stars
Reviewed on 2/4/2026
Dr Wigley is the best, and I am very grateful to be his patient.
5 out of 5 stars
Reviewed on 1/21/2026
I love Dr wigley. He sits next to you and listens and writes down notes. He has already reviewed your history and test results. He is clear and kind and compassionate. He is a genius.
5 out of 5 stars
Reviewed on 1/14/2026
Dr. Wigley is terrific. I really appreciate his knowledge and expertise. He's an excellent physician and a really good person
5 out of 5 stars
Reviewed on 1/14/2026
Dr wigley is the best and listens to everything you tell him.
5 out of 5 stars
Reviewed on 1/13/2026
Dr Wigley is the best! He is kind and thoughtful. He always has time for me.
5 out of 5 stars
Reviewed on 12/30/2025
I have been seeing Dr. Wigley for over 40 years. I've recommended him to many people. He has helped me with my condition tremendously. His expertise, knowledge, care, and dedication, is the reason I go to him. I have tremendous respect for him. He is a wonderful doctor.
5 out of 5 stars
Reviewed on 12/23/2025
Dr Wigley is gentle and kind. He is serious about his job.
5 out of 5 stars
Reviewed on 12/16/2025
I have been a patient of Dr Wigley's for 42 years! He is the best!
5 out of 5 stars
Reviewed on 12/11/2025
Dr Wigley is so kind and compassionate. His knowledge about Scleroderma is first rate.
5 out of 5 stars
Reviewed on 12/10/2025
The best!
5 out of 5 stars
Reviewed on 12/4/2025
I fully trust Dr Wigley with my life. I actually trust Dr Wigley opinion more then any other doctor or hospital I'm blessed to have him for a doctor
5 out of 5 stars
Reviewed on 12/3/2025
Dr Wigley has a ton of experience with and knowledge of Scleroderma.I feel confident about his care of me.
5 out of 5 stars
Reviewed on 12/3/2025
Dr. Wigley is a very special Dr. He really cares about his patients and is very thorough.
5 out of 5 stars
Reviewed on 11/20/2025
Dr. Wigley is a fantastic physician; he saved my life 15 years ago and keeps looking after me.
5 out of 5 stars
Reviewed on 11/13/2025
Dr. Wigley is the best doctor iI have ever seen. Very knowledgeable and caring.
5 out of 5 stars
Reviewed on 10/30/2025
Dr. Wigley is very thorough and reviews all test results carefully. He explains the test results and what they indicate about my health. He is compassionate and listens to my questions and concerns. He goes out of his way to bring information from the internet for me to consider or to further explain an issue.
5 out of 5 stars
Reviewed on 10/29/2025
Dr Fred Wigley is the best!!!!
5 out of 5 stars
Reviewed on 10/23/2025
Dr. Wigley is an outstanding physician. He has deep medical knowledge and demonstrates empathy with the patient. His scientific approach to problem solving is superb.
5 out of 5 stars
Reviewed on 10/22/2025
Dr Wigley is wonderful and old fashion physician who takes time evaluates pt and listens
5 out of 5 stars
Reviewed on 10/22/2025
I have been going to Dr.Wigley since 1994 there are no doctors as caring and dedicated today like him. I also worked in the medical field . He is top notch
5 out of 5 stars
Reviewed on 9/29/2025
We rely on Dr. Wigley and the JHU team to assist in looking after our health. They are a valued partner
5 out of 5 stars
Reviewed on 9/23/2025
Very good doctor . Always very caring, And always very knowledgeable and helpful about any questions and gave me all the time I needed. Always very respectful .
5 out of 5 stars
Reviewed on 9/23/2025
Excellent
5 out of 5 stars
Reviewed on 9/17/2025
I feel truly fortunate to be under the care of Dr. Fredrick Wigley. His deep expertise, compassionate approach, and dedication to his patients set him apart as an outstanding physician. He takes the time to listen, explains complex medical issues with clarity, and provides care that is both thorough and reassuring. Dr. Wigley's commitment to advancing knowledge in his field while always prioritizing the well-being of his patients makes him not only an exceptional doctor but also a deeply trusted guide on the healthcare journey.
5 out of 5 stars
Reviewed on 9/17/2025
Very responsive. He is always making sure to go above and beyond to ensure that I am okay and that I have what I need.
5 out of 5 stars
Reviewed on 9/17/2025
Best doctor I have ever had.
5 out of 5 stars
Reviewed on 9/11/2025
Wonderful always helps me explain things to me and is very very courteous
5 out of 5 stars
Reviewed on 9/9/2025
Dr Wigley excels. In knowledge of my condition. He is also kind and compassionate.
5 out of 5 stars
Reviewed on 9/9/2025
He s kind and an excellent provider
5 out of 5 stars
Reviewed on 9/4/2025
Dr Wigley is wonderful. I have seen a patient of his for many years.
5 out of 5 stars
Reviewed on 9/3/2025
He took his time, was thorough, and very informative.
5 out of 5 stars
Reviewed on 9/2/2025
Great doctor listens to my concerns and is extremely interested in how I am progressing
5 out of 5 stars
Reviewed on 9/2/2025
Dr.Wigley is the best Dr. I have. I dont know what I would do without him.
5 out of 5 stars
Reviewed on 8/27/2025
Dr Wigley is the best! Im very lucky to have him take care of me@
5 out of 5 stars
Reviewed on 8/20/2025
Very kind, patient, knowledgeable and caring.
5 out of 5 stars
Reviewed on 8/19/2025
Dr. Wigley has never disappointed in any way over the years I have been seeing him since 2004.
5 out of 5 stars
Reviewed on 8/19/2025
Dr. Wigley is THE best!!
5 out of 5 stars
Reviewed on 8/14/2025
Doctor Wigley is amazing. Really the best doctor I have ever seen. So thorough and he goes above and beyond to provide the best care.
5 out of 5 stars
Reviewed on 8/13/2025
Dr. Wigley is an excellent doctor! I am fortunate to be one of his patients.
5 out of 5 stars
Reviewed on 8/13/2025
Dr. Fredrick Wigley is the most compassionate, caring, knowledgeable, concerned doctor I have ever gone to. He is the absolute best doctor!! He always responds to my texts through mychart within approximately 12 hours, he always shares test results with me instead of having a nurse do it, and is very thorough during an office visit. He is a provider like you will not see anywhere else.
5 out of 5 stars
Reviewed on 8/12/2025
Simply the best!
5 out of 5 stars
Reviewed on 8/12/2025
Dr Wigley is an incredible provider.
5 out of 5 stars
Reviewed on 8/6/2025
Dr. Wigley was extremely attentive, meticulous, detailed in his explanations, direct, and gave me security and peace of mind throughout the process of my condition, my future follow-ups, and my health care.
5 out of 5 stars
Reviewed on 7/31/2025
He's the best!
5 out of 5 stars
Reviewed on 7/30/2025
Exceptional!
5 out of 5 stars
Reviewed on 7/24/2025
Dr. Wigley is by far the most caring, comprehensive, and informative doctor I have seen. My health is as good as it has been all these years because of his care. I am grateful.
5 out of 5 stars
Reviewed on 7/23/2025
Phenomenal doctor
5 out of 5 stars
Reviewed on 7/23/2025
Dr. Wigley was extremely thorough, compassionate, and knowledgeable. He shared information in a way that was very easy to understand.
5 out of 5 stars
Reviewed on 7/22/2025
I have been a patient of Dr. Wigley for over 20 years. Also, I live out of state and have to travel a distance to get to the JH facility at the Eastern Ave location. I would not continue a patient relationship with Dr. Wigley if I wasn't pleased with him as my MD.
5 out of 5 stars
Reviewed on 6/26/2025
Dr Wigley is one of the best physicians out there not only is his knowledge impeccable but his empathy and concern for my wellbeing is unmatched. I have been seeing him for 19 years and have never had a visit that was not exceptional.
5 out of 5 stars
Reviewed on 6/25/2025
Excellent
5 out of 5 stars
Reviewed on 6/18/2025
Dr Wigley is exceptional and my hero
5 out of 5 stars
Reviewed on 6/5/2025
I love Dr Wigley. He is the most caring and compassionate dr I have ever been to