Calixto-Hope Lucas Jr., MD

Director, Clinical Neuropathology Service

Associate Program Director, Anatomic Pathology Residency Program

Associate Program Director, Neuropathology Fellowship Program

Dr. Calixto-Hope G. Lucas Jr. is an Associate Professor of Pathology at the Johns Hopkins University School of Medicine. He serves as Director of the Clinical Neuropathology Service, Associate Program Director of the Anatomic Pathology Residency and Neuropathology Fellowship Training Programs, and Course Director of Organ Systems Foundations of Medicine: Neoplasia. 

Dr. Lucas earned his B.S. degree in Molecular and Cellular Biology & History of Science, Medicine, and Technology from Johns Hopkins University in 2014 and M.D. degree from University of California, San Francisco in 2018. He continued on at University of California, San Francisco and completed residency training in anatomic pathology and fellowship training in neuropathology while serving as pathology chief resident. His main academic interest is in brain tumor pathology, with emphasis on molecular neuropathology, pediatric gliomas, and neoplasms arising in patients with tumor predisposition syndromes. He frequently works in collaboration with clinical colleagues and has expertise in next-generation sequencing, DNA methylation profiling, and spatial proteomic and transcriptomic techniques. He continues to leverage multiplatform sequencing approaches to refine existing codification schemes and develop assays that can be translated to clinical neuropathology and neuro-oncology practice.

Sidney Kimmel Comprehensive Cancer Center